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01-11-2006 | Poster Presentation

New molecular tools and optical technologies to dissect CXCR4 function in breast cancer

Authors: PW Thavasu, F Festy, R Springall, K Ryder, R Waters, M Kelleher, S Pinder, C Gillett, T Ng

Published in: Breast Cancer Research | Special Issue 2/2006

Excerpt

The objective was to study the relationship between CXCR4 expression (total and conformational subsets) and disease outcome in malignant breast disease. Initially, a retrospective study evaluating the clinical significance of CXCR4 expression (as determined by immunohistochemistry and immunofluroscence) with histopathological grade and clinical outcome of breast cancer patients were evaluated. …

Holland JD, Kochetkova M, Akekawatcai C, Dottore M, Lopez A, McColl SR: Differential functional activation of chemokine receptor CXCR4 is mediated by G proteins in breast cancer cells. Cancer Res. 2006, 66: 4117-4124. 10.1158/0008-5472.CAN-05-1631.CrossRefPubMed

Title: New molecular tools and optical technologies to dissect CXCR4 function in breast cancer
Authors: PW Thavasu
F Festy
R Springall
K Ryder
R Waters
M Kelleher
S Pinder
C Gillett
T Ng
Publication date: 01-11-2006
Publisher: BioMed Central
Published in: Breast Cancer Research / Issue Special Issue 2/2006
Electronic ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr1580

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