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Published in: Breast Cancer Research 2/2005

01-06-2005 | Poster Presentation

Methylation profiling of carcinogenesis-associated genes in sporadic breast cancer

Authors: M Nemtsova, V Zemlyakova, E Kusnetsova, V Strelnikov, L Lyubchenko, D Zaletayev

Published in: Breast Cancer Research | Special Issue 2/2005

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Excerpt

Aberrant methylation of normally unmethylated CpG islands has been associated with transcriptional inactivation of defined tumor suppressor genes (TSG) in human cancer. Abnormal methylation therefore serves as an alternative to the genetic loss of a tumor suppressor gene function by deletion or mutation. …
Metadata
Title
Methylation profiling of carcinogenesis-associated genes in sporadic breast cancer
Authors
M Nemtsova
V Zemlyakova
E Kusnetsova
V Strelnikov
L Lyubchenko
D Zaletayev
Publication date
01-06-2005
Publisher
BioMed Central
Published in
Breast Cancer Research / Issue Special Issue 2/2005
Electronic ISSN: 1465-542X
DOI
https://doi.org/10.1186/bcr1147

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