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Health Economics Review

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Open Access 01-12-2013 | Review

Health-related quality of life questionnaires in lung cancer trials: a systematic literature review

Authors: Kathrin Damm, Nicole Roeske, Christian Jacob

Published in: Health Economics Review | Issue 1/2013

Abstract

Background

Lung cancer is one of the leading causes of cancer deaths. Treatment goals are the relief of symptoms and the increase of overall survival. With the rising number of treatment alternatives, the need for comparable assessments of health-related quality of life (HRQoL) parameters grows. The aim of this paper was to identify and describe measurement instruments applied in lung cancer patients under drug therapy.

Methods

We conducted a systematic literature review at the beginning of 2011 using the electronic database Pubmed.

Results

A total of 43 studies were included in the review. About 17 different measurement instruments were identified, including 5 generic, 5 cancer-specific, 4 lung cancer-specific and 3 symptom-specific questionnaires. In 29 studies at least 2 instruments were used. In most cases these were cancer and lung cancer-specific ones. The most frequently used instruments are the EORTC QLQ-C30 and its lung cancer modules LC13 or LC17. Only 5 studies combined (lung) cancer-specific questionnaires with generic instruments.

Conclusions

The EORTC-C30 and EORTC-LC13 are the most frequently used health-related quality of life measurement instruments in pharmacological lung cancer trials.

Available only for authorised users

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Title: Health-related quality of life questionnaires in lung cancer trials: a systematic literature review
Authors: Kathrin Damm
Nicole Roeske
Christian Jacob
Publication date: 01-12-2013
Publisher: Springer Berlin Heidelberg
Published in: Health Economics Review / Issue 1/2013
Electronic ISSN: 2191-1991
DOI: https://doi.org/10.1186/2191-1991-3-15

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Health-related quality of life questionnaires in lung cancer trials: a systematic literature review

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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