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Annals of Intensive Care
Published in: Annals of Intensive Care 1/2014

Open Access 01-12-2014 | Review

Anemia and red blood cell transfusion in critically ill cardiac patients

Authors: Geneviève Du Pont-Thibodeau, Karen Harrington, Jacques Lacroix

Published in: Annals of Intensive Care | Issue 1/2014

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Abstract

Anemia and red blood cell (RBC) transfusion occur frequently in hospitalized patients with cardiac disease. In this narrative review, we report the epidemiology of anemia and RBC transfusion in hospitalized adults and children (excluding premature neonates) with cardiac disease, and on the outcome of anemic and transfused cardiac patients. Both anemia and RBC transfusion are common in cardiac patients, and both are associated with mortality. RBC transfusion is the only way to rapidly treat severe anemia, but is not completely safe. In addition to hemoglobin (Hb) concentration, the determinant(s) that should drive a practitioner to prescribe a RBC transfusion to cardiac patients are currently unclear. In stable acyanotic cardiac patients, Hb level above 70 g/L in children and above 70 to 80 g/L in adults appears safe. In cyanotic children, Hb level above 90 g/L appears safe. The appropriate threshold Hb level for unstable cardiac patients and for children younger than 28 days is unknown. The optimal transfusion strategy in cardiac patients is not well characterized. The threshold at which the risk of anemia outweighs the risk of transfusion is not known. More studies are needed to determine when RBC transfusion is indicated in hospitalized patients with cardiac disease.
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Metadata
Title
Anemia and red blood cell transfusion in critically ill cardiac patients
Authors
Geneviève Du Pont-Thibodeau
Karen Harrington
Jacques Lacroix
Publication date
01-12-2014
Publisher
Springer Paris
Published in
Annals of Intensive Care / Issue 1/2014
Electronic ISSN: 2110-5820
DOI
https://doi.org/10.1186/2110-5820-4-16

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