Skip to main content
Top
Published in: European Journal of Medical Research 1/2014

Open Access 01-12-2014 | Research

Clinical characteristics of congenital cervical atresia based on anatomy and ultrasound: a retrospective study of 32 cases

Authors: Zhihong Xie, Xiaoping Zhang, Jiandong Liu, Ningzhi Zhang, Hong Xiao, Yongying Liu, Liang Li, Xiaoying Liu

Published in: European Journal of Medical Research | Issue 1/2014

Login to get access

Abstract

Background

To explore the clinical characteristics of congenital cervical atresia.

Methods

This retrospective analysis included 32 cases of congenital cervical atresia treated from March 1984 to September 2010. The anatomic location, ultrasonic features, surgical treatments, and outcomes were recorded.

Results

Based on clinical characteristics observed during preoperative ultrasound and intraoperative exploration, congenital cervical atresia was divided into four types. Type I (n?=?22/32, 68.8%) is incomplete cervical atresia. Type II (n?=?5/32, 15.6%) defines a short and solid cervix with a round end; the structure lacked uterosacral and cardinal ligament attachments to the lower uterine body. Type III (n?=?2/32, 6.3%) is complete cervical atresia, in which the lowest region of the uterus exhibited a long and solid cervix. Type IV (n?=?3/32, 9.4%) defines the absence of a uterine isthmus, in which no internal os was detected, and a blind lumen was found under the uterus.

Conclusions

Observations of clinical characteristics of congenital cervical atresia based on the anatomy and ultrasound may inform diagnosis and treatment strategy.
Appendix
Available only for authorised users
Literature
1.
go back to reference Hampton HL, Meeks GR, Bates GW, Wiser WL: Pregnancy after successful vaginoplasty and cervical stenting for partial atresia of the cervix. Obstet Gynecol 1990, 76: 900–901. 10.1097/00006250-199011001-00001PubMedCrossRef Hampton HL, Meeks GR, Bates GW, Wiser WL: Pregnancy after successful vaginoplasty and cervical stenting for partial atresia of the cervix. Obstet Gynecol 1990, 76: 900–901. 10.1097/00006250-199011001-00001PubMedCrossRef
2.
go back to reference Anttila L, Penttilä TA, Suikkari AM: Successful pregnancy after in-vitro fertilization and transmyometrial embryo transfer in a patient with congenital atresia of cervix: case report. Hum Reprod 1999, 14(6):1647–1649. 10.1093/humrep/14.6.1647PubMedCrossRef Anttila L, Penttilä TA, Suikkari AM: Successful pregnancy after in-vitro fertilization and transmyometrial embryo transfer in a patient with congenital atresia of cervix: case report. Hum Reprod 1999, 14(6):1647–1649. 10.1093/humrep/14.6.1647PubMedCrossRef
3.
go back to reference Charavarty B, Konar H, Chovvdhury NNJ: Pregnancies after reconstructive surgery for congenital cervicovaginal atresia. Am Gynecol 2000, 183: 421–423. 10.1067/mob.2000.105740CrossRef Charavarty B, Konar H, Chovvdhury NNJ: Pregnancies after reconstructive surgery for congenital cervicovaginal atresia. Am Gynecol 2000, 183: 421–423. 10.1067/mob.2000.105740CrossRef
4.
go back to reference Deffarges JV, Haddad B, Musset R, Paniel BJ: Utero-vaginal anastomosis in women with uterine cervix atresia: long-term follow-up and reproductive performance. A study of 18 cases. Hum Reprod 2001, 16(8):1722–1725. 10.1093/humrep/16.8.1722PubMedCrossRef Deffarges JV, Haddad B, Musset R, Paniel BJ: Utero-vaginal anastomosis in women with uterine cervix atresia: long-term follow-up and reproductive performance. A study of 18 cases. Hum Reprod 2001, 16(8):1722–1725. 10.1093/humrep/16.8.1722PubMedCrossRef
5.
go back to reference Buttram VC, Gibbons WE: Mullerian anomalies: a proposed classification (an analysis of 144 cases). Fertil Steril 1979, 32: 40–46.PubMed Buttram VC, Gibbons WE: Mullerian anomalies: a proposed classification (an analysis of 144 cases). Fertil Steril 1979, 32: 40–46.PubMed
6.
go back to reference Acien P, Acien M, Sanchez-Ferrer M: Complex malformations of the female genital tract. New types and revision of classification. Hum Reprod 2004, 19: 2377–2384. 10.1093/humrep/deh423PubMedCrossRef Acien P, Acien M, Sanchez-Ferrer M: Complex malformations of the female genital tract. New types and revision of classification. Hum Reprod 2004, 19: 2377–2384. 10.1093/humrep/deh423PubMedCrossRef
7.
go back to reference Acien P, Acien MI: The history of female genital tract malformation classifications and proposal of an updated system. Hum Reprod Update 2011, 17: 693–705. 10.1093/humupd/dmr021PubMedCrossRef Acien P, Acien MI: The history of female genital tract malformation classifications and proposal of an updated system. Hum Reprod Update 2011, 17: 693–705. 10.1093/humupd/dmr021PubMedCrossRef
8.
go back to reference Oppelt P, Renner SP, Brucker S, Strissel PL, Strick R, Oppelt PG, Doerr HG, Schott GE, Hucke J, Wallwiener D, Beckmann MW: The VCUAM (Vagina Cervix Uterus Adnex-associated Malformation) classification: a new classification for genital malformations. Fertil Steril 2005, 84(5):1493–1497. 10.1016/j.fertnstert.2005.05.036PubMedCrossRef Oppelt P, Renner SP, Brucker S, Strissel PL, Strick R, Oppelt PG, Doerr HG, Schott GE, Hucke J, Wallwiener D, Beckmann MW: The VCUAM (Vagina Cervix Uterus Adnex-associated Malformation) classification: a new classification for genital malformations. Fertil Steril 2005, 84(5):1493–1497. 10.1016/j.fertnstert.2005.05.036PubMedCrossRef
9.
go back to reference Grimbizis GF, Gordts S, Di Spiezio Sardo A, Brucker S, De Angelis C, Gergolet M, Li TC, Tanos V, Brölmann H, Gianaroli L, Campo R: The ESHRE/ESGE consensus on the classification of female genital tract congenital anomalies. Hum Reprod 2013, 28(8):2032–2044. 10.1093/humrep/det098PubMedPubMedCentralCrossRef Grimbizis GF, Gordts S, Di Spiezio Sardo A, Brucker S, De Angelis C, Gergolet M, Li TC, Tanos V, Brölmann H, Gianaroli L, Campo R: The ESHRE/ESGE consensus on the classification of female genital tract congenital anomalies. Hum Reprod 2013, 28(8):2032–2044. 10.1093/humrep/det098PubMedPubMedCentralCrossRef
10.
go back to reference Leng J, Lang J, Lian L, Huang R, Liu Z, Sun D, Zhu L: Congenital vaginal atresia: report of 16 cases. Zhonghua Fu Chan Ke Za Zhi 2002, 37(4):217–219.PubMed Leng J, Lang J, Lian L, Huang R, Liu Z, Sun D, Zhu L: Congenital vaginal atresia: report of 16 cases. Zhonghua Fu Chan Ke Za Zhi 2002, 37(4):217–219.PubMed
11.
go back to reference Shirota K, Fukuoka M, Tsujioka H, Inoue Y, Kawarabayashi T: A normal uterus communicating with a double cervix and the vagina: a müllerian anomaly without any present classification. Fertil Steril 2009, 91(3):935. e1–935.e3PubMedCrossRef Shirota K, Fukuoka M, Tsujioka H, Inoue Y, Kawarabayashi T: A normal uterus communicating with a double cervix and the vagina: a müllerian anomaly without any present classification. Fertil Steril 2009, 91(3):935. e1–935.e3PubMedCrossRef
12.
go back to reference Suganuma N, Furuhashi M, Moriwaki T, Tsukahara S, Ando T, Ishihara Y: Management of missed abortion in a patient with congenital cervical atresia. Fertil Steril 2002, 77(5):1071–1073. 10.1016/S0015-0282(02)03067-4PubMedCrossRef Suganuma N, Furuhashi M, Moriwaki T, Tsukahara S, Ando T, Ishihara Y: Management of missed abortion in a patient with congenital cervical atresia. Fertil Steril 2002, 77(5):1071–1073. 10.1016/S0015-0282(02)03067-4PubMedCrossRef
13.
go back to reference Zhihong X, Ling L, Xiaoping Z, Ningzhi Z, Hong X, Yongying L, Chen L: Vaginal vestibule mucosa associated with pudendo femoral skin flap vaginoplasty and tracheloplasty. Chin J Obstet Gynecol 2003, 38(1):45–46. Zhihong X, Ling L, Xiaoping Z, Ningzhi Z, Hong X, Yongying L, Chen L: Vaginal vestibule mucosa associated with pudendo femoral skin flap vaginoplasty and tracheloplasty. Chin J Obstet Gynecol 2003, 38(1):45–46.
14.
go back to reference Rampone B, Filippeschi M, Di Martino M, Marrelli D, Pedrazzani C, Grimaldi L, Cerullo G, Caruso S, Pinto E, Roviello F: Mayer-Rokitansky-Küster-Hauser syndrome presenting as vaginal atresia: report of two cases. G Chir 2008, 29(4):165–167.PubMed Rampone B, Filippeschi M, Di Martino M, Marrelli D, Pedrazzani C, Grimaldi L, Cerullo G, Caruso S, Pinto E, Roviello F: Mayer-Rokitansky-Küster-Hauser syndrome presenting as vaginal atresia: report of two cases. G Chir 2008, 29(4):165–167.PubMed
15.
go back to reference Simpson JL, Photopulos G: Hereditary aspects of ovarian and testicular neoplasia. Birth Defects Orig Artic Ser 1976, 12(1):51–60.PubMed Simpson JL, Photopulos G: Hereditary aspects of ovarian and testicular neoplasia. Birth Defects Orig Artic Ser 1976, 12(1):51–60.PubMed
16.
go back to reference Thomas JC, Brock JW: Vaginal substitution: attempts to create the ideal replacement. J Urol 2007, 178(5):1855–1859. 10.1016/j.juro.2007.07.007PubMedCrossRef Thomas JC, Brock JW: Vaginal substitution: attempts to create the ideal replacement. J Urol 2007, 178(5):1855–1859. 10.1016/j.juro.2007.07.007PubMedCrossRef
17.
go back to reference Fatum M, Rojansky N, Shushan A: Septate uterus with cervical duplication: rethinking the development of müllerian anomalies. Gynecol Obstet Invest 2003, 55(3):186–188. 10.1159/000071535PubMedCrossRef Fatum M, Rojansky N, Shushan A: Septate uterus with cervical duplication: rethinking the development of müllerian anomalies. Gynecol Obstet Invest 2003, 55(3):186–188. 10.1159/000071535PubMedCrossRef
18.
go back to reference Panici PB, Bellati F, Boni T, Francescangeli F, Frati L, Marchese C: Vaginoplasty using autologous in vitro cultured vaginal tissue in a patient with Mayer-von-Rokitansky-Kuster-Hauser syndrome. Hum Reprod 2007, 22(7):2025–2028. 10.1093/humrep/dem096PubMedCrossRef Panici PB, Bellati F, Boni T, Francescangeli F, Frati L, Marchese C: Vaginoplasty using autologous in vitro cultured vaginal tissue in a patient with Mayer-von-Rokitansky-Kuster-Hauser syndrome. Hum Reprod 2007, 22(7):2025–2028. 10.1093/humrep/dem096PubMedCrossRef
19.
go back to reference El Saman AM: Combined retropubic balloon vaginoplasty and laparoscopic canalization: a novel blend of techniques provides a minimally invasive treatment for cervicovaginal aplasia. Am J Obstet Gynecol 2009, 201(3):333. e1–5PubMedCrossRef El Saman AM: Combined retropubic balloon vaginoplasty and laparoscopic canalization: a novel blend of techniques provides a minimally invasive treatment for cervicovaginal aplasia. Am J Obstet Gynecol 2009, 201(3):333. e1–5PubMedCrossRef
20.
go back to reference El Saman AM: Endoscopically monitored canalization for treatment of congenital cervical atresia: the least invasive approach. Fertil Steril 2010, 94(1):313–316. 10.1016/j.fertnstert.2009.02.079PubMedCrossRef El Saman AM: Endoscopically monitored canalization for treatment of congenital cervical atresia: the least invasive approach. Fertil Steril 2010, 94(1):313–316. 10.1016/j.fertnstert.2009.02.079PubMedCrossRef
Metadata
Title
Clinical characteristics of congenital cervical atresia based on anatomy and ultrasound: a retrospective study of 32 cases
Authors
Zhihong Xie
Xiaoping Zhang
Jiandong Liu
Ningzhi Zhang
Hong Xiao
Yongying Liu
Liang Li
Xiaoying Liu
Publication date
01-12-2014
Publisher
BioMed Central
Published in
European Journal of Medical Research / Issue 1/2014
Electronic ISSN: 2047-783X
DOI
https://doi.org/10.1186/2047-783X-19-10

Other articles of this Issue 1/2014

European Journal of Medical Research 1/2014 Go to the issue