Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Systematic Reviews
Published in: Systematic Reviews 1/2013

Open Access 01-12-2013 | Research

Cochrane diagnostic test accuracy reviews

Authors: Mariska MG Leeflang, Jonathan J Deeks, Yemisi Takwoingi, Petra Macaskill

Published in: Systematic Reviews | Issue 1/2013

Login to get access

Abstract

In 1996, shortly after the founding of The Cochrane Collaboration, leading figures in test evaluation research established a Methods Group to focus on the relatively new and rapidly evolving methods for the systematic review of studies of diagnostic tests. Seven years later, the Collaboration decided it was time to develop a publication format and methodology for Diagnostic Test Accuracy (DTA) reviews, as well as the software needed to implement these reviews in The Cochrane Library. A meeting hosted by the German Cochrane Centre in 2004 brought together key methodologists in the area, many of whom became closely involved in the subsequent development of the methodological framework for DTA reviews. DTA reviews first appeared in The Cochrane Library in 2008 and are now an integral part of the work of the Collaboration.
Appendix
Available only for authorised users
Literature
1.
Feinstein AR: Misguided efforts and future challenges for research on “diagnostic tests”. J Epidemiol Comm Health. 2002, 56: 330-332. 10.1136/jech.56.5.330.CrossRef
2.
Mulherin SA, Miller WC: Spectrum bias or spectrum effect? Subgroup variation in diagnostic test evaluation. Ann Intern Med. 2002, 137: 598-602. 10.7326/0003-4819-137-7-200210010-00011.CrossRefPubMed
3.
Whiting PF, Rutjes AW, Westwood ME, Mallett S, QUADAS-2 Steering Group: A systematic review classifies sources of bias and variation in diagnostic test accuracy studies. J Clin Epidemiol. 2013, 66: 1093-1104. 10.1016/j.jclinepi.2013.05.014.CrossRefPubMed
4.
Lord SJ, Irwig L, Simes RJ: When is measuring sensitivity and specificity sufficient to evaluate a diagnostic test, and when do we need randomized trials?. Ann Intern Med. 2006, 144: 850-855. 10.7326/0003-4819-144-11-200606060-00011.CrossRefPubMed
5.
Irwig L, Tosteson AN, Gatsonis C, Lau J, Colditz G, Chalmers TC, Mosteller F: Guidelines for meta-analyses evaluating diagnostic tests. Ann Intern Med. 1994, 120: 667-676. 10.7326/0003-4819-120-8-199404150-00008.CrossRefPubMed
6.
Leeflang MM, Deeks JJ, Gatsonis C, Bossuyt PM, Cochrane Diagnostic Test Accuracy Working Group: Systematic reviews of diagnostic test accuracy. Ann Intern Med. 2008, 149: 889-897. 10.7326/0003-4819-149-12-200812160-00008.CrossRefPubMedPubMedCentral
7.
Leeflang MMG, Debets-Ossenkopp YJ, Visser CE, Scholten RJ, Hooft L, Bijlmer HA, Reitsma JB, Bossuyt PMM, Vandenbroucke-Grauls CM: Galactomannan detection for invasive aspergillosis in immunocompromized patients. Cochrane Database Syst Rev. 2008, 4: CD007394-PubMed
8.
9.
Gianrossi R, Detrano R, Mulvihill D, Lehmann K, Dubach P, Colombo A, McArthur D, Froelicher V: Exercise-induced ST depression in the diagnosis of coronary artery disease. A meta-analysis. Circulation. 1989, 80: 87-98. 10.1161/01.CIR.80.1.87.CrossRefPubMed
10.
Kardaun JW, Kardaun OJ: Comparative diagnostic performance of three radiological procedures for the detection of lumbar disk herniation. Methods Inf Med. 1990, 29: 12-22.PubMed
11.
McClish D: Combining and combining area estimates across studies or strata. Med Decis Making. 1992, 12: 274-279. 10.1177/0272989X9201200405.CrossRefPubMed
12.
Littenberg B, Moses LE: Estimating diagnostic accuracy from multiple conflicting reports: a new meta-analytic method. Med Decis Making. 1993, 13: 313-321. 10.1177/0272989X9301300408.CrossRefPubMed
13.
Moses L, Shapiro D, Littenberg B: Combining independent studies of a diagnostic test into a summary ROC curve: Data-analytic approaches and some additional considerations. Stat Med. 1993, 12: 1293-1316. 10.1002/sim.4780121403.CrossRefPubMed
14.
Irwig L, Macaskill P, Glasziou P, Fahey M: Meta-analytic methods for diagnostic test accuracy. J Clin Epidemiol. 1995, 48: 119-130. 10.1016/0895-4356(94)00099-C.CrossRefPubMed
15.
16.
De-Vet HC, van der Weijden T, Muris JW, Heyrman J, Buntinx F, Knottnerus JA: Systematic reviews of diagnostic research. Considerations about assessment and incorporation of methodological quality. Eur J Epidemiol. 2001, 17: 301-306. 10.1023/A:1012751326462.CrossRefPubMed
17.
Bossuyt PM, Irwig L, Craig J, Glasziou P: Comparative accuracy: assessing new tests against existing diagnostic pathways. BMJ. 2006, 332: 1089-1092. 10.1136/bmj.332.7549.1089.CrossRefPubMedPubMedCentral
18.
Leeflang MM, Scholten RJ, Rutjes AW, Reitsma JB, Bossuyt PM: Use of methodological search filters to identify diagnostic accuracy studies can lead to the omission of relevant studies. J Clin Epidemiol. 2006, 59: 234-240. 10.1016/j.jclinepi.2005.07.014.CrossRefPubMed
19.
Whiting P, Westwood M, Beynon R, Burke M, Sterne JA, Glanville J: Inclusion of methodological filters in searches for diagnostic test accuracy studies misses relevant studies. J Clin Epidemiol. 2011, 64: 602-607. 10.1016/j.jclinepi.2010.07.006.CrossRefPubMed
20.
Lijmer JG, Bossuyt PM, Heisterkamp SH: Exploring sources of heterogeneity in systematic reviews of diagnostic tests. Stat Med. 2002, 21: 1525-1537. 10.1002/sim.1185.CrossRefPubMed
21.
Whiting P, Rutjes AW, Reitsma JB, Glas AS, Bossuyt PM, Kleijnen J: Sources of variation and bias in studies of diagnostic accuracy: a systematic review. Ann Intern Med. 2004, 140: 189-202. 10.7326/0003-4819-140-3-200402030-00010.CrossRefPubMed
22.
Whiting P, Rutjes AWS, Reitsma JB, Bossuyt PMM, Kleijnen J: The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Method. 2003, 3: 25-10.1186/1471-2288-3-25.CrossRef
23.
Reitsma JB, Rutjes AWS, Whiting P, Vlassov VV, Leeflang MMG, Deeks JJ: Chapter 9: Assessing methodological quality. Cochrane Handbook for Systematic Reviews of Diagnostic Test Accuracy. Edited by: Deeks JJ, Bossuyt PM, Gatsonis C. 2009, The Cochrane Collaboration [http://​srdta.​cochrane.​org/​]
24.
Whiting PF, Rutjes AW, Westwood ME, Mallett S, Deeks JJ, Reitsma JB, Leeflang MM, Sterne JA, Bossuyt PM, The QUADAS-2 Group: QUADAS-2: a revised tool for the quality assessment of diagnostic accuracy studies. Ann Intern Med. 2011, 155: 529-536. 10.7326/0003-4819-155-8-201110180-00009.CrossRefPubMed
25.
Rutter CM, Gatsonis CA: Regression methods for meta-analysis of diagnostic test data. Acad Radiol. 1995, 2 (Suppl 1): S48-56.PubMed
26.
Van-Houwelingen HC, Zwinderman AH, Stijnen T: A bivariate approach to meta-analysis. Stat Med. 1993, 12: 2273-2284. 10.1002/sim.4780122405.CrossRefPubMed
27.
Rutter CM, Gatsonis CA: A hierarchical regression approach to meta-analysis of diagnostic test accuracy evaluations. Stat Med. 2001, 20: 2865-2884. 10.1002/sim.942.CrossRefPubMed
28.
Macaskill P: Empirical Bayes estimates generated in a hierarchical summary ROC analysis agreed closely with those of a full Bayesian analysis. J Clin Epidemiol. 2004, 57: 925-932. 10.1016/j.jclinepi.2003.12.019.CrossRefPubMed
29.
Reitsma JB, Glas AS, Rutjes AW, Scholten RJ, Bossuyt PM, Zwinderman AH: Bivariate analysis of sensitivity and specificity produces informative summary measures in diagnostic reviews. J Clin Epidemiol. 2005, 58: 982-990. 10.1016/j.jclinepi.2005.02.022.CrossRefPubMed
30.
Harbord RM, Whiting P, Sterne JA, Egger M, Deeks JJ, Shang A, Bachmann LM: An empirical comparison of methods for meta-analysis of diagnostic accuracy showed hierarchical models are necessary. J Clin Epidemiol. 2008, 61: 1095-1103. 10.1016/j.jclinepi.2007.09.013.CrossRefPubMed
31.
Harbord RM, Deeks JJ, Egger M, Whiting P, Sterne JA: A unification of models for meta-analysis of diagnostic accuracy studies. Biostatistics. 2007, 8: 239-251. 10.1093/biostatistics/kxl004.CrossRefPubMed
32.
Glas AS, Roos D, Deutekom M, Zwinderman AH, Bossuyt PM, Kurth KH: Tumor markers in the diagnosis of primary bladder cancer. A systematic review. J Urol. 2003, 169: 1975-1982. 10.1097/01.ju.0000067461.30468.6d.CrossRefPubMed
33.
Macaskill P, Gatsonis C, Deeks JJ, Harbord RM, Takwoingi Y: Chapter 10: Analysing and Presenting Results. Handbook for Systematic Reviews of Diagnostic Test Accuracy. Edited by: Deeks JJ, Bossuyt PM, Gatsonis C. 2010, The Cochrane Collaboration. [http://​srdta.​cochrane.​org/​]
34.
Song F, Khan KS, Dinnes J, Sutton AJ: Asymmetric funnel plots and publication bias in meta-analyses of diagnostic accuracy. Int J Epidemiol. 2002, 31: 88-95. 10.1093/ije/31.1.88.CrossRefPubMed
35.
Deeks JJ, Macaskill P, Irwig L: The performance of tests of publication bias and other sample size effects in systematic reviews of diagnostic test accuracy was assessed. J Clin Epidemiol. 2005, 58: 882-893. 10.1016/j.jclinepi.2005.01.016.CrossRefPubMed
36.
Takwoingi Y, Leeflang MM, Deeks JJ: Empirical evidence of the importance of comparative studies of diagnostic test accuracy. Ann Intern Med. 2013, 158: 544-554. 10.7326/0003-4819-158-7-201304020-00006.CrossRefPubMed
37.
Hamza TH, Arends LR, Van-Houwelingen HC, Stijnen T: Multivariate random effects meta-analysis of diagnostic tests with multiple thresholds. BMC Med Res Methodol. 2009, 9: 73-10.1186/1471-2288-9-73.CrossRefPubMedPubMedCentral
38.
Ferrante di-Ruffano L, Hyde CJ, McCaffery KJ, Bossuyt PM, Deeks JJ: Assessing the value of diagnostic tests: a framework for designing and evaluating trials. BMJ. 2012, 344: e686-10.1136/bmj.e686.CrossRefPubMed
39.
Schünemann HJ, Oxman AD, Brozek J, Glasziou P, Jaeschke R, Vist GE, Williams JW, Kunz R, Craig J, Montori VM, Bossuyt PM, Guyatt GH, The GRADE Working Group: Grading quality of evidence and strength of recommendations for diagnostic tests and strategies. BMJ. 2008, 336: 1106-1110. 10.1136/bmj.39500.677199.AE.CrossRefPubMedPubMedCentral
Metadata
Title
Cochrane diagnostic test accuracy reviews
Authors
Mariska MG Leeflang
Jonathan J Deeks
Yemisi Takwoingi
Petra Macaskill
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Systematic Reviews / Issue 1/2013
Electronic ISSN: 2046-4053
DOI
https://doi.org/10.1186/2046-4053-2-82

Other articles of this Issue 1/2013

Systematic Reviews 1/2013 Go to the issue

Protocol

Clinical risk factors for late intestinal toxicity after radiotherapy: a systematic review protocol

Protocol

THERACOM: a systematic review of the evidence base for interventions to improve Therapeutic Communications between black and minority ethnic populations and staff in specialist mental health services

Methodology

Individual patient data meta-analysis of beta-blockers in heart failure: rationale and design

Protocol

Interventions to decrease the risk of adverse cardiac events for post-surgery or chemotherapy patients taking serotonin (5-HT3) receptor antagonists: protocol for a systematic review and network meta-analysis

Commentary

The evolution of assessing bias in Cochrane systematic reviews of interventions: celebrating methodological contributions of the Cochrane Collaboration

Protocol

Behavioural activation interventions for depressed individuals with a chronic physical illness: a systematic review protocol