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Clinical and Translational Allergy
Published in: Clinical and Translational Allergy 1/2013

Open Access 01-12-2013 | Review

The skin prick test – European standards

Authors: Lucie Heinzerling, Adriano Mari, Karl-Christian Bergmann, Megon Bresciani, Guido Burbach, Ulf Darsow, Stephen Durham, Wytske Fokkens, Mark Gjomarkaj, Tari Haahtela, Ana Todo Bom, Stefan Wöhrl, Howard Maibach, Richard Lockey

Published in: Clinical and Translational Allergy | Issue 1/2013

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Abstract

Skin prick testing is an essential test procedure to confirm sensitization in IgE-mediated allergic disease in subjects with rhinoconjunctivitis, asthma, urticaria, anapylaxis, atopic eczema and food and drug allergy. This manuscript reviews the available evidence including Medline and Embase searches, abstracts of international allergy meetings and position papers from the world allergy literature. The recommended method of prick testing includes the appropriate use of specific allergen extracts, positive and negative controls, interpretation of the tests after 15 – 20 minutes of application, with a positive result defined as a wheal ≥3 mm diameter. A standard prick test panel for Europe for inhalants is proposed and includes hazel (Corylus avellana), alder (Alnus incana), birch (Betula alba), plane (Platanus vulgaris), cypress (Cupressus sempervirens), grass mix (Poa pratensis, Dactilis glomerata, Lolium perenne, Phleum pratense, Festuca pratensis, Helictotrichon pretense), Olive (Olea europaea), mugwort (Artemisia vulgaris), ragweed (Ambrosia artemisiifolia), Alternaria alternata (tenuis), Cladosporium herbarum, Aspergillus fumigatus, Parietaria, cat, dog, Dermatophagoides pteronyssinus, Dermatophagoides farinae, and cockroach (Blatella germanica). Standardization of the skin test procedures and standard panels for different geographic locations are encouraged worldwide to permit better comparisons for diagnostic, clinical and research purposes.
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Metadata
Title
The skin prick test – European standards
Authors
Lucie Heinzerling
Adriano Mari
Karl-Christian Bergmann
Megon Bresciani
Guido Burbach
Ulf Darsow
Stephen Durham
Wytske Fokkens
Mark Gjomarkaj
Tari Haahtela
Ana Todo Bom
Stefan Wöhrl
Howard Maibach
Richard Lockey
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Clinical and Translational Allergy / Issue 1/2013
Electronic ISSN: 2045-7022
DOI
https://doi.org/10.1186/2045-7022-3-3

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