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Clinical Sarcoma Research
Published in: Clinical Sarcoma Research 1/2013

Open Access 01-12-2013 | Research

Localized Ewing sarcoma of the tibia

Authors: Takeshi G Kashima, Nimali G Gamage, Uta Dirksen, Christopher L M H Gibbons, Simon J Ostlere, Nicholas A Athanasou

Published in: Clinical Sarcoma Research | Issue 1/2013

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Abstract

Ewing sarcoma (ES) is a high-grade malignant primary round cell tumour of bone in which there is commonly extension into extraosseous soft tissues at the time of diagnosis. This report details the clinical, radiological and pathological features of a case of ES of the tibia in which there was extensive osseous involvement but no infiltration beyond the periosteum into surrounding soft tissue. We also record the findings of one other ES case that exhibited similar behaviour. Both cases were male, involved the tibia and had the characteristic t (11;22) (q24;q12) translocation. No recurrence of tumour or metastasis has been seen in these two cases, both of which have had 6 years follow-up. Our findings indicate that there is heterogeneity in the behaviour of ES and show that localized ES is associated with a good prognosis.
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Metadata
Title
Localized Ewing sarcoma of the tibia
Authors
Takeshi G Kashima
Nimali G Gamage
Uta Dirksen
Christopher L M H Gibbons
Simon J Ostlere
Nicholas A Athanasou
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Clinical Sarcoma Research / Issue 1/2013
Electronic ISSN: 2045-3329
DOI
https://doi.org/10.1186/2045-3329-3-2

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