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Journal of Neurodevelopmental Disorders
Published in: Journal of Neurodevelopmental Disorders 1/2013

Open Access 01-12-2013 | Review

Resting state EEG abnormalities in autism spectrum disorders

Authors: Jun Wang, Jamie Barstein, Lauren E Ethridge, Matthew W Mosconi, Yukari Takarae, John A Sweeney

Published in: Journal of Neurodevelopmental Disorders | Issue 1/2013

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Abstract

Autism spectrum disorders (ASD) are a group of complex and heterogeneous developmental disorders involving multiple neural system dysfunctions. In an effort to understand neurophysiological substrates, identify etiopathophysiologically distinct subgroups of patients, and track outcomes of novel treatments with translational biomarkers, EEG (electroencephalography) studies offer a promising research strategy in ASD. Resting-state EEG studies of ASD suggest a U-shaped profile of electrophysiological power alterations, with excessive power in low-frequency and high-frequency bands, abnormal functional connectivity, and enhanced power in the left hemisphere of the brain. In this review, we provide a summary of recent findings, discuss limitations in available research that may contribute to inconsistencies in the literature, and offer suggestions for future research in this area for advancing the understanding of ASD.
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Metadata
Title
Resting state EEG abnormalities in autism spectrum disorders
Authors
Jun Wang
Jamie Barstein
Lauren E Ethridge
Matthew W Mosconi
Yukari Takarae
John A Sweeney
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Journal of Neurodevelopmental Disorders / Issue 1/2013
Print ISSN: 1866-1947
Electronic ISSN: 1866-1955
DOI
https://doi.org/10.1186/1866-1955-5-24

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