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Published in: Journal of Neurodevelopmental Disorders 1/2012

Open Access 01-12-2012 | Review

Social attention: a possible early indicator of efficacy in autism clinical trials

Authors: Geraldine Dawson, Raphael Bernier, Robert H Ring

Published in: Journal of Neurodevelopmental Disorders | Issue 1/2012

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Abstract

For decades, researchers have sought to clarify the nature of the social communication impairments in autism, highlighting impaired or atypical 'social attention' as a key measurable construct that helps to define the core impairment of social communication. In this paper, we provide an overview of research on social attention impairments in autism and their relation to deficiencies in neural circuitry related to social reward. We offer a framework for considering social attention as a potential moderator or mediator of response to early behavioral intervention, and as an early indicator of efficacy of behavioral and/or pharmacological treatments aimed at addressing the social impairments in autism.
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Metadata
Title
Social attention: a possible early indicator of efficacy in autism clinical trials
Authors
Geraldine Dawson
Raphael Bernier
Robert H Ring
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Neurodevelopmental Disorders / Issue 1/2012
Print ISSN: 1866-1947
Electronic ISSN: 1866-1955
DOI
https://doi.org/10.1186/1866-1955-4-11

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