Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress 2023 EHA Congress 2023 ASCO Annual Meeting
Clinical Collections
Advances in Alzheimer’s

At a glance: The ONWARDS insulin icodec trials

A round-up of the ONWARDS phase 3 clinical trials evaluating the novel weekly insulin icodec in people with diabetes.
ADVANCED SEARCH
Log in
Top
Italian Journal of Pediatrics
Published in: Italian Journal of Pediatrics 2/2014

Open Access 01-12-2014 | Meeting abstract

Neonatal hyperbilirubinemia

Authors: Matteo Dal Ben, Silvia Gazzin, Claudio Tiribelli

Published in: Italian Journal of Pediatrics | Special Issue 2/2014

Login to get access

Excerpt

Unconjugated hyperbilirubinemia is a common condition in the first week of postnatal life. Low levels of bilirubin exert antioxidant effects, but some neonates may develop very high levels of unconjugated bilirubin (UCB), with an increase of the unbound free fraction (Bf), able to diffuse through the blood brain barrier. …
Literature
1.
Conlee JW, Shapiro SM: Development of cerebellar hypoplasia in jaundiced Gunn rats: a quantitative light microscopic analysis. Acta Neuropathol. 1997, 93 (5): 450-60. 10.1007/s004010050639.CrossRefPubMed
2.
Shapiro SM: Chronic bilirubin encephalopathy: diagnosis and outcome. Semin Fetal Neonatal Med. 2010, 15 (3): 157-63. 10.1016/j.siny.2009.12.004. doi: 10.1016/j.siny.2009.12.004. Epub 2010 Jan 29CrossRefPubMed
3.
Coda Zabetta CD, Iskander IF, Greco C, Bellarosa C, Demarini S, Tiribelli C, Wennberg RP: Bilistick: a low-cost point-of-care system to measure total plasma bilirubin. Neonatology. 2013, 103 (3): 177-81. 10.1159/000345425. doi: 10.1159/000345425. Epub 2012 Dec 22CrossRefPubMed
4.
Morris BH, Oh W, Tyson JE: Aggressive vs. conservative phototherapy for infants with extremely low birth weight. N Engl J Med. 2008, 359: 1885-96. 10.1056/NEJMoa0803024.PubMedCentralCrossRefPubMed
5.
Watchko JF, Tiribelli C: Bilirubin-induced neurologic damage--mechanisms and management approaches. N Engl J Med. 2013, 369 (21): 2021-30. 10.1056/NEJMra1308124. doi: 10.1056/NEJMra1308124CrossRefPubMed
6.
Gazzin S, Zelenka J, Zdrahalova L, Konickova R, Zabetta CC, Giraudi PJ, Berengeno AL, Raseni A, Robert MC, Vitek L, Tiribelli C: Bilirubin accumulation and Cyp mRNA expression in selected brain regions of jaundiced Gunn rat pups. Pediatr Res. 2012, 71 (6): 653-60. 10.1038/pr.2012.23. doi: 10.1038/pr.2012.23. Epub 2012 Feb 15CrossRefPubMed
7.
Robert MC, Furlan G, Rosso N, Gambaro SE, Apitsionak F, Vianello E, Tiribelli C, Gazzin S: Alterations in the cell cycle in the cerebellum of hyperbilirubinemic gunn rat: a possible link with apoptosis?. PLoS One. 2013, 8 (11): e79073-10.1371/journal.pone.0079073. doi: 10.1371/journal.pone.0079073. eCollection 2013PubMedCentralCrossRefPubMed
Metadata
Title
Neonatal hyperbilirubinemia
Authors
Matteo Dal Ben
Silvia Gazzin
Claudio Tiribelli
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue Special Issue 2/2014
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/1824-7288-40-S2-A10

Other articles of this Special Issue 2/2014

Italian Journal of Pediatrics 2/2014 Go to the issue

Meeting abstract

Are all Italian newborns equal?

Meeting abstract

Mode of delivery and gut microbiota

Meeting abstract

Delivery and late preterm birth

Meeting abstract

The late preterm in low income

Meeting abstract

Cranial ultrasound screening in late preterm infants

Meeting abstract

Immune development in late preterm neonates