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Italian Journal of Pediatrics
Published in: Italian Journal of Pediatrics 1/2014

Open Access 01-12-2014 | Meeting abstract

The children with microcytosis

Authors: Bruno Nobili, Sofia MR Matarese, Francesca Rossi

Published in: Italian Journal of Pediatrics | Special Issue 1/2014

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Excerpt

Microcytosis is decrease of red blood cells (RBCs) size. The RBCs size is measured by the mean corpuscular volume (MCV). In the children, MCV varies by age and sex and so it must be always compared with sex and age-based norms. A MCV less than the 5th percentile defines the children microcytosis . The most frequent causes of microcytosis are iron deficiency anaemia (IDA) and haemoglobinopathies [1]. …
Literature
1.
Oski FA: A diagnostic approach to the anemic patient. Nathan and Oski’s Hematology of Infancy and Childhood. 2003, Philadelphia, Pa.: Saunders, 409-418. 6
2.
Urrechaga E, Borque L, Escanero JF: Erythrocyte and Reticulocyte Parameters in Iron Deficiency and Thalassemia. J Clin Lab Anal. 2011, 25: 223-228. 10.1002/jcla.20462.CrossRefPubMed
3.
Schoorl M, Linssen J, Villanueva MM, NoGuera JA, Martinez PH, Bartels PC: Efficacy of Advanced Discriminating Algorithms for Screening on Iron-Deficiency Anemia and β-Thalassemia Trait. Am J Clin Pathol. 2012, 138: 300-304. 10.1309/AJCP20UTTCAYKUDX.CrossRefPubMed
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Camaschella C: How I manage patients with atypical microcytic anaemia. Br J Haematol. 2012, 160: 12-24.CrossRefPubMed
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De Falco L, Sanchez M, Silvestri L, Kannengiesser C, Muckenthaler MU, Iolascon A, Gouya L, Camaschella C, Beaumont C: Iron refractory iron deficiency anemia. Haematologica. 2013, 98: 845-53. 10.3324/haematol.2012.075515.PubMedCentralCrossRefPubMed
Metadata
Title
The children with microcytosis
Authors
Bruno Nobili
Sofia MR Matarese
Francesca Rossi
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue Special Issue 1/2014
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/1824-7288-40-S1-A14

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