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Italian Journal of Pediatrics
Published in: Italian Journal of Pediatrics 1/2013

Open Access 01-12-2013 | Review

Gastrointestinal function development and microbiota

Authors: Antonio Di Mauro, Josef Neu, Giuseppe Riezzo, Francesco Raimondi, Domenico Martinelli, Ruggiero Francavilla, Flavia Indrio

Published in: Italian Journal of Pediatrics | Issue 1/2013

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Abstract

The intestinal microbiota plays an important role in the development of post-natal gastrointestinal functions of the host. Recent advances in our capability to identify microbes and their function offer exciting opportunities to evaluate the complex cross talk between microbiota, intestinal barrier, immune system and the gut-brain axis. This review summarizes these interactions in the early colonization of gastrointestinal tract with a major focus on the role of intestinal microbiota in the pathogenesis of feeding intolerance in preterm newborn. The potential benefit of early probiotic supplementation opens new perspectives in case of altered intestinal colonization at birth as preventive and therapeutic agents.
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Metadata
Title
Gastrointestinal function development and microbiota
Authors
Antonio Di Mauro
Josef Neu
Giuseppe Riezzo
Francesco Raimondi
Domenico Martinelli
Ruggiero Francavilla
Flavia Indrio
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Italian Journal of Pediatrics / Issue 1/2013
Electronic ISSN: 1824-7288
DOI
https://doi.org/10.1186/1824-7288-39-15

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