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Head & Neck Oncology
Published in: Head & Neck Oncology 1/2011

Open Access 01-12-2011 | Case report

Rheumatoid arthritis mimicking metastatic squamous cell carcinoma

Authors: Fernando Gomez-Rivera, Adel K El-Naggar, Nandita Guha-Thakurta, Michael E Kupferman

Published in: Head & Neck Oncology | Issue 1/2011

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Abstract

We report a case of a cervical rheumatoid nodule in close relation to the hyoid bone mimicking a metastatic carcinoma. A 74-year-old female with a 15-year history of rheumatoid arthritis (RA) on treatment with methotrexate presented with tenderness of the right base of tongue. Imaging demonstrated a 1.4 cm cystic lesion at the hyoid bone. Biopsies were unsuccessful and the patient required surgical resection of the mass. A trans-cervical approach was used. Pathology revealed a necrotizing granuloma compatible with rheumatoid etiology. The clinician should be aware that, in a patient with a neck mass, in the presence of active RA, rheumatoid nodules should be part of the differential diagnosis.
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Charlin B, Brazeau-Lamontagne L, Levesque RY, et al: Cricoarytenoiditis in rheumatoid arthritis: comparison of fibrolaryngoscopic and high resolution computerized tomographic findings. J Otolaryngol. 1985, 14: 381-386.PubMed
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Lawry GV, Finerman ML, Hanafee WN, et al: Laryngeal involvement in rheumatoid arthritis. A clinical, laryngoscopic, and computerized tomographic study. Arthritis Rheum. 1984, 27: 873-882. 10.1002/art.1780270806.CrossRefPubMed
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Metadata
Title
Rheumatoid arthritis mimicking metastatic squamous cell carcinoma
Authors
Fernando Gomez-Rivera
Adel K El-Naggar
Nandita Guha-Thakurta
Michael E Kupferman
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Head & Neck Oncology / Issue 1/2011
Electronic ISSN: 1758-3284
DOI
https://doi.org/10.1186/1758-3284-3-26

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