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Open Access 01-12-2009 | Review

Understanding the nature and mechanism of foot pain

Authors: Fiona Hawke, Joshua Burns

Published in: Journal of Foot and Ankle Research | Issue 1/2009

Abstract

Approximately one-quarter of the population are affected by foot pain at any given time. It is often disabling and can impair mood, behaviour, self-care ability and overall quality of life. Currently, the nature and mechanism underlying many types of foot pain is not clearly understood. Here we comprehensively review the literature on foot pain, with specific reference to its definition, prevalence, aetiology and predictors, classification, measurement and impact. We also discuss the complexities of foot pain as a sensory, emotional and psychosocial experience in the context of clinical practice, therapeutic trials and the placebo effect. A deeper understanding of foot pain is needed to identify causal pathways, classify diagnoses, quantify severity, evaluate long term implications and better target clinical intervention.

Badlissi F, Dunn J, Link C, Keysor J, McKinlay J, Felson D: Foot musculoskeletal disorders, pain, and foot-related functional limitation in older persons. J Am Soc Geriatr Dent. 2005, 53: 1029-1033. 10.1111/j.1532-5415.2005.53315.x.

Hill C, Gill T, Menz H, Taylor A: Prevalence and correlates of foot pain in a population-based study: the North West Adelaide health study. J Foot Ankle Res. 2008, 1 (1): 2-10.1186/1757-1146-1-2.PubMedPubMedCentral

Menz HB, Lord SR: Foot pain impairs balance and functional ability in community-dwelling older people. Journal of the American Podiatric Medical Association. 2001, 91: 222-229.PubMed

Garrow AP, Silman AJ, Macfarlane GJ: The Chesire foot pain and disability survey: a population survey assessing prevalence and associations. Pain. 2004, 110: 378-384. 10.1016/j.pain.2004.04.019.PubMed

Menz HB, Tiedemann A, Kwan MMS, Plumb K, Lord SR: Foot pain in community-dwelling older people: an evaluation of the Manchester Foot Pain and Disability Index. Rheumatology. 2006, 45: 863-867. 10.1093/rheumatology/kel002.PubMed

Menz HB, Morris ME, Lord SR: Foot and ankle risk factors for falls in older people: a prospective study. J Gerontol. 2006, 61A: 866-870.

Menz HB, Lord SR: The contribution of foot problems to mobility impairment and falls in community-dwelling older people. Journal of the American Geriatric Society. 2001, 49: 1651-1656. 10.1111/j.1532-5415.2001.49275.x.

Benvenuti F, Ferrucci L, Guralnik JM, Gangemi S, Baroni A: Foot pain and disability in older persons: an epidemiologic survey. J Am Geriatr Soc. 1995, 43: 479-484.PubMed

Novak P, Burger H, Marincek C, Meh D: Influence of foot pain on walking ability of diabetic patients. J Rehabil Med. 2004, 36: 249-252. 10.1080/16501970410029816.PubMed

10.

Leveille SG, Guralnik JM, Ferrucci L, Hirsch R, Simonsick EM, Hochberg MC: Foot pain and disability in older women. Am J Epidemiol. 1998, 148: 657-665.PubMed

11.

Keysor JJ, Dunn JE, Link CL, Badlissi F, Felson DT: Are foot disorders associated with functional limitation and disability among community-dwelling older adults?. J Aging Health. 2005, 17: 734-752. 10.1177/0898264305280998.PubMed

12.

Buttke J: Stepping Up Foot Injury Diagnosis: Jones, Lisfranc, and Charcot. Nurse Pract. 2005, 30: 46-52. 10.1097/00006205-200512000-00008.PubMed

13.

Ertugrul M, Baktiroglu S, Salman S, Unal S, Aksoy M, Berberoglu K, Calangu S: The diagnosis of osteomyelitis of the foot in diabetes: microbiological examination vs. magnetic resonance imaging and labelled leucocyte scanning. Diabet Med. 2006, 23: 649-653. 10.1111/j.1464-5491.2006.01887.x.PubMed

14.

Crawford F, Atkins D, Edwards J: Interventions for treating plantar heel pain. Cochrane Database Syst Rev. 2003, CD000416-

15.

Hawke F, Burns J, Radford J, du Toit V: Custom-made foot orthoses for the treatment of foot pain. Cochrane Database Syst Rev. 2008, CD006801-

16.

Stern S: Ankle and foot pain. Prim Care. 1988, 15: 809-826.PubMed

17.

Mann R: Pain in the foot. 1. Evaluation of foot pain and identification of associated problems. Postgrad Med. 1987, 82: 154-157.PubMed

18.

Mann R: Pain in the foot. 2. Causes of pain in the hindfoot, midfoot, and forefoot. Postgrad Med. 1987, 82: 167-171.PubMed

19.

Wood B, Warfield C: Foot pain – from bad shoes to aberrant genes. Hosp Pract (Off Ed). 1987, 22: 107-122.

20.

Merskey H, Bogduk N, (Eds): Classification of Chronic Pain. 1994, Seattle: IASP Press, Second

21.

Bennet RM: Emerging concepts in the neurobiology of chronic pain: evidence of abnormal sensory processing in fibromyalgia. Mayo Clin Proc. 1999, 74: 385-398.

22.

Kidd B, Urban L: Mechanisms of inflammatory pain. Br J Anaesth. 2001, 87: 3-11. 10.1093/bja/87.1.3.PubMed

23.

Vanderah TW: Pathophysiology of Pain. Med Clin North Am. 2007, 91: 1-12. 10.1016/j.mcna.2006.10.006.PubMed

24.

Maganaris CN, Narici MV, Almekinders LC, Maffulli N: Biomechanics and pathophysiology of overuse tendon injuries ideas on insertional tendinopathy. Sports Med. 2004, 34: 1005-1017. 10.2165/00007256-200434140-00005.PubMed

25.

McPoil T, Hunt G: Evaluation and management of foot and ankle disorders: present position and future directions. J Orthop Sports Phys Ther. 1995, 21: 381-PubMed

26.

Mueller MJ, Maluf KS: Tissue adaptation to physical stress: a proposed "physical stress theory" to guide physical therapist practice, education, and research. Phys Ther. 2002, 82: 383-403.PubMed

27.

Garrow A, Papageorgiou A, Silman A, Thomas E, Jayson M, Macfarlane G: The grading of Hallux Valgus: the Manchester scale. J Am Podiatr Med Assoc. 2001, 91: 74-78.PubMed

28.

McRae R: Clinical orthopaedic examination. 1997, Edinburgh: Churchill Livingstone

29.

Myerson M, Shereff M: The pathological anatomy of claw and hammer toes. J Bone Joint Surg. 1989, 71: 45-49.PubMed

30.

Frey C, Thompson F, Smith J, Sanders M, Horstman H: American Orthopedic Foot and Ankle Society women's shoe survey. Foot Ankle. 1993, 14: 78-81.PubMed

31.

Menz H, Morris M: Footwear characteristics and foot problems in older people. Gerontology. 2005, 51: 346-351. 10.1159/000086373.PubMed

32.

Dawson J, Thorogood M, Marks S, Juszczak E, Dodd C, Lavis G, Fitzpatrick R: The prevalence of foot problems in older women: a cause for concern. Journal of Public Health Medicine. 2002, 24: 77-84. 10.1093/pubmed/24.2.77.PubMed

33.

Cedraschi C, Nordin M, Nachemson A, Vischer T: Health care providers should use a common language in relation to low back pain patients. Baillieres Clin Rheumatol. 1998, 12: 1-8. 10.1016/S0950-3579(98)80003-4.PubMed

34.

Von Korff M, Miglioretti DL: A prognostic approach to defining chronic pain. Pain. 2005, 117: 304-313. 10.1016/j.pain.2005.06.017.PubMed

35.

Katz WA, Rothenberg R: Section 3: the nature of pain: pathophysiology. Journal of Clinical Rheumatology. 2005, 11: S11-S15. 10.1097/01.rhu.0000158686.43637.af.PubMed

36.

Besson JM: The neurobiology of pain. Lancet. 1999, 353: 1610-1615. 10.1016/S0140-6736(99)01313-6.PubMed

37.

Schaible HG, Richter F: Pathophysiology of pain. Langenbecks Arch Surg. 2004, 389: 237-243. 10.1007/s00423-004-0468-9.PubMed

38.

Fink WA: The pathophysiology of acute pain. Emerg Med Clin N Am. 2005, 23: 277-284. 10.1016/j.emc.2004.12.001.

39.

Pasero C: Pathophysiology of neuropathic pain. Pain Manag Nurs. 2004, 5: 3-8. 10.1016/j.pmn.2004.10.002.PubMed

40.

Donaldson GW, Chapmana CR, Nakamuraa Y, Bradshawa DH, Jacobsona RC, Chapmanb CN: Pain and the defense response: structural equation modeling reveals a coordinated psychophysiological response to increasing painful stimulation. Pain. 2003, 102: 97-108. 10.1016/s0304-3959(02)00351-2.PubMed

41.

Schaible HG, Schmelz M, Tegeder I: Pathophysiology and treatment of pain in joint disease. Adv Drug Deliv Rev. 2006, 58: 323-342. 10.1016/j.addr.2006.01.011.PubMed

42.

Willis W, Westlund K: Neuroanatomy of the pain system and of the pathways that modulate pain. J Clin Neurophysiol. 1997, 14: 2-31. 10.1097/00004691-199701000-00002.PubMed

43.

Melzack R, Wall P: Pain mechanisms: a new theory. Science Wash CD. 1965, 150: 971-979. 10.1126/science.150.3699.971.

44.

Jensen TS, Gottrup H, Sindrup SH, Bach FW: The clinical picture of neuropathic pain. Eur J Pharmacol. 2001, 429: 1-11. 10.1016/S0014-2999(01)01302-4.PubMed

45.

Koltzenburg M: Stability and plasticity of nociceptor function and their relationship to provoked and ongoing pain. Seminars in Neuroscience. 1995, 7: 199-210. 10.1006/smns.1995.0023.

46.

Bennett GA: Animal models of neuropathic pain. Progress in Pain Research and Management. Edited by: Gebhart G, Hammond D, Jensen T. 1994, Seattle: IASP Publications, 2: 495-510.

47.

Zimmermann M: Pathobiology of neuropathic pain. Eur J Pharmacol. 2001, 429: 23-37. 10.1016/S0014-2999(01)01303-6.PubMed

48.

Waxman SG: The molecular pathophysiology of pain: abnormal expression of sodium channel genes and its contributions to hyperexcitability of primary sensory neurons. Pain. 1999, S133-S140. 10.1016/S0304-3959(99)00147-5. Supplement 6

49.

Bogduk N: Complex regional pain syndrome. Curr Opin Anaesthesiol. 2001, 14: 541-546. 10.1097/00001503-200110000-00013.PubMed

50.

Köck F, Borisch N, Koester B, Grifka J: Complex regional pain syndrome type I (CRPS I). Pathophysiology, diagnostics, and therapy. Orthopade. 2003, 32: 418-431. 10.1007/s00132-003-0468-4.PubMed

51.

Scott A, Khan K, Cook J, Duronio V: What is 'inflammation'? Are we ready to move beyond celsus?. Br J Sports Med. 2004, 38: 248-249. 10.1136/bjsm.2003.011221.PubMedPubMedCentral

52.

Tracy R: The five cardinal signs of inflammation. J Gerontol A Biol Sci Med Sci. 2006, 61: 1051-1052.PubMed

53.

Loeser JD, Melzack R: Pain: an overview. Lancet. 1999, 353: 1607-1609. 10.1016/S0140-6736(99)01311-2.PubMed

54.

Dray A: Kinins and their receptors in hyperalgesia. Can J Pharmacol. 1997, 75: 704-712. 10.1139/cjpp-75-6-704.

55.

Schaible H, Grubb B: Afferent and spinal mechanisms of joint pain. Pain. 1993, 55: 5-54. 10.1016/0304-3959(93)90183-P.PubMed

56.

Dunajcik L: Chronic nonmalignant pain. Pain: Clinical manual. Edited by: McCaffery M, Pasero C. 1999, Mosby: St. Louis, 467-521.

57.

Gibson S, Helme R: Age-related differences in pain perception and report. Clin Geriatr Med. 2001, 17: 433-456. 10.1016/S0749-0690(05)70079-3.PubMed

58.

Gagliese L, Katz J, Melzack R: Pain in the elderly. Textbook of Pain. Edited by: Wall P, Melzack R. 1999, New York: Churchill Livingstone

59.

Gibson S, Helme R: Age-related differences in pain perception and report. Clinics in Geriatric Medicine. 2001, 17: 433-456. 10.1016/S0749-0690(05)70079-3.PubMed

60.

Lautenbacher S, Strian F: Similarities in age differences in heat pain perception and thermal sensitivity. Funct Neurol. 1991, 6 (2): 129-135.PubMed

61.

Jensen R, Rasmussen B, Pedersen B, Lous I, Olesen J: Cephalic muscle tenderness and pressure pain threshold in a general population. Pain. 1992, 48: 197-10.1016/0304-3959(92)90059-K.PubMed

62.

Chakour M, Gibson S, Helme R: The effect of age on A delta and C fibre thermal pain perception. Pain. 1996, 64:

63.

Farrar JT, Portenoy RK, Berlin JA, Kinman JL, Strom BL: Defining the clinically important difference in pain outcome measures. Pain. 2000, 88: 287-294. 10.1016/S0304-3959(00)00339-0.PubMed

64.

Turner JA, Franklin G, Heagerty PJ, Wu R, Egan K, Fulton-Kehoe D, Gluck JV, Wickizer TM: The association between pain and disability. Pain. 2004, 112: 307-314. 10.1016/j.pain.2004.09.010.PubMed

65.

Landorf K, Burns J: Chapter 10: Health Outcome Assessment. Merriman's assessment of the lower limb. Edited by: Yates B. 2008, London: Churchill Livingstone, 3: 3

66.

Budiman-Mak E, Conrad K, Roach K: The Foot Function Index: a measure of foot pain and disability. J Clin Epidemiol. 1991, 44: 561-570. 10.1016/0895-4356(91)90220-4.PubMed

67.

Bennett P, C P, Wearing S, Baglioni A: Development and validation of a questionnaire designed to measure foot health status. J Am Podiatr Med Assoc. 1998, 88: 419-428.PubMed

68.

Abetz L, Sutton M, Brady L, McNulty P, Gagnon D: The Diabetic Foot Ulcer Scale (DFS): a quality of life instrument for use in clinical trials. Practical Diabetes International. 2002, 19: 167-175. 10.1002/pdi.356.

69.

Garrow A, Papageorgiou A, Silman A, Thomas E, Jayson M, Macfarlane G: Development and validation of a questionnaire to assess disabling foot pain. Pain. 2000, 85: 107-113. 10.1016/S0304-3959(99)00263-8.PubMed

70.

Rowan K: The development and validation of a multi-dimensional measure of chronic foot pain: the ROwan Foot Pain Assessment Questionnaire (ROFPAQ). Foot Ankle Int. 2001, 22: 795-809.PubMed

71.

Johanson N, Liang M, Daltroy L, Rudicel S, Richmond J: American Academy of Orthopaedic Surgeons Lower Limb Outcomes Assessment Instruments. Reliability, validity, and sensitivity to change. J Bone Joint Surg. 2004, 86: 902-909.PubMed

72.

Roth-Isigkeit A, Thyen U, Stoven H, Schgwarzenberger J, Schumucker P: Pain among children and adolescents: restrictions in daily living and triggering factors. Pediatrics. 2005, 115: e152-162. 10.1542/peds.2004-0682.PubMed

73.

Reyes-Gibby CC, Aday L, Cleelandm C: Impact of pain on self-rated health on the community dwelling older adults. Pain. 2002, 95: 75-82. 10.1016/S0304-3959(01)00375-X.PubMed

74.

Strassels S, Cynn D, Carr DB: Health status and chronic pain in managed care: Instruments and assessment. Managed Care and Pain. Edited by: Lande SD, Kulich RJ. 2000, American Pain Society, 141-171.

75.

Hunfeld J, Perquin C, Hazebroek-Kampschreur , Passchier J, van Suijlekom-Smit L, Wouden vd: Physically unexplained chronic pain and its impact on children and their families: The mother's perception. Psychol Psychother. 2002, 75: 251-260. 10.1348/147608302320365172.PubMed

76.

Roelofs , et al: Fear of movement and (re)injury in chronic musculoskeletal pain. Pain. 2007

77.

Palermo T, Kiska R: Subjective sleep disturbances in adolescents with chronic pain: relationship to daily functioning and quality of life. J Pain. 2005, 6: 201-207. 10.1016/j.jpain.2004.12.005.PubMed

78.

Hunfeld J, Perquin C, Bertina W, Hazebroek-Kampschreur A, van Suijlekom-Smit L, Koes B, Wouden van der J, Passchier J: Stability of pain parameters and pain-related quality of life in adolescents with persistent pain: a three-year follow-up. Clin J Pain. 2002, 18: 99-106. 10.1097/00002508-200203000-00005.PubMed

79.

Scudds R, Robertson J: Pain factors associated with physical disability in a sample of community-dwelling senior citizens. J Gerontol A Biol Sci Med Sci. 2000, 55 (7): M393-M399.PubMed

80.

American Pain Society: Chronic pain in America: Roadblocks to relief. 1999, [http://www.ampainsoc.org/links/roadblocks/]

81.

Strine T, Hootman J, Chapman D, Okoro C, Balluz L: Health-related quality of life, health risk behaviors, and disability among adults with pain-related activity difficulty. Am J Public Health. 2005, 95: 2042-2048. 10.2105/AJPH.2005.066225.PubMedPubMedCentral

82.

Von Korff M, Simon G: The relationship between pain and depression. Br J Psychiatry Suppl. 1996, 30: 101-108.PubMed

83.

Asghari A, Ghaderi N, Ashory A: The prevalence of pain among residents of nursing homes and the impact of pain on their mood and quality of life. Arch Iran Med. 2006, 9: 368-373.PubMed

84.

Williams D, Robinson M, Geisser M: Pain beliefs: assessment and utility. Pain. 1994, 59: 71-78. 10.1016/0304-3959(94)90049-3.PubMed

85.

Thomas E, Colleen M, Renier B, Jeanette A, Palcher B: Chronic pain, depression, and quality of life: correlations and predictive value of the SF-36. Pain Med. 2003, 4: 331-339. 10.1111/j.1526-4637.2003.03040.x.

86.

Skevington S: Investigating the relationship between pain and discomfort and quality of life, using the WHOQOL. Pain. 1998, 76: 395-406. 10.1016/S0304-3959(98)00072-4.PubMed

87.

Ribu L, Rustoen T, Birkeland K, Hanestad B, Paul S, Miaskowski C: The prevalence and occurrence of diabetic foot ulcer pain and its impact on health-related quality of life. J Pain. 2006, 7: 290-299. 10.1016/j.jpain.2005.12.002.PubMed

88.

Dysvik E, Lindstrøm TC, Eikeland O-J, Natvig GK: Health-related quality of life and pain beliefs among people suffering from chronic pain. Pain Manag Nurs. 2004, 5: 66-74. 10.1016/j.pmn.2003.11.003.PubMed

89.

Turk D, Okifuji A, Scharff L: Chronic pain and depression: role of perceived impact and perceived control in different age cohorts. Pain. 1995, 61: 93-101. 10.1016/0304-3959(94)00167-D.PubMed

90.

Sawyer P, Bodner E, Ritchie C, Allman R: Pain and pain medication use in community-dwelling older adults. Am J Geriatr Pharmacother. 2006, 4: 316-324. 10.1016/j.amjopharm.2006.12.005.PubMed

91.

Simon G, VonKorff M, Piccinelli M, Fullerton C, Ormel J: An international study of the relation between somatic symptoms and depression. N Engl J Med. 1999, 341: 1329-1335. 10.1056/NEJM199910283411801.PubMed

92.

Tugwell P, Shea B, Boers M, Brooks P, Simon L, Strand V, Wells G, (editors): Evidence-based Rheumatology. 2004, London: BMJ books

93.

Keeley R, Smith M, Miller J: Somatoform symptoms and treatment nonadherence in depressed family medicine outpatients. Arch Fam Med. 2000, 9: 46-54. 10.1001/archfami.9.1.46.PubMed

94.

Chen J, Devine A, Dick IM, Dhaliwal S, Prince RL: Prevalence of lower extremity pain and its association with functionality and quality of life in elderly women in Australia. J Rheumatol. 2003, 30: 2689-2693.PubMed

95.

Ware JE, Snow KK, Kosinski M, Gandek B: SF-36 health survey manual & interpretation guide. 2000, Lincoln: QualityMetric Incorporated

96.

Gerstle D, All A, Wallace D: Quality of life and chronic nonmalignant pain. Pain Manag Nurs. 2001, 2:

97.

Katz N: The impact of pain management on quality of life. J Pain Symptom Manage. 2002, 24: S38-S47. 10.1016/S0885-3924(02)00411-6.PubMed

98.

Schlenk E, Erlen JA, Dunbar-Jacob J, McDowell J, Engberg S, Sereika S, al e: Health-related quality of life in chronic disorders: A comparison across studies using the MOS SF-36. Qual Life Res. 1998, 7: 57-65. 10.1023/A:1008836922089.PubMed

99.

Burns J, Crosbie J, Ouvrier R, Hunt A: Effective orthotic therapy for the painful cavus foot. A randomised controlled trial. J Am Podiatr Med Assoc. 2006, 96: 205-211.PubMed

100.

Roos E, Engström M, Söderberg B: Foot orthoses for the treatment of plantar fasciitis. Foot Ankle Int. 2006, 27: 606-611.PubMed

101.

Torkki M, Malmivaara A, Seitsalo S, Hoikka V, Laippala P, Paavolainen P: Surgery vs orthosis vs watchful waiting for hallux valgus: a randomised controlled trial. J Am Med Assoc. 2001, 285: 2474-2480. 10.1001/jama.285.19.2474.

102.

Gatchel RJ: Perspectives on pain: A historical overview. Psychosocial Factors in Pain Critical Perspectives. Edited by: Gatchel RJ, Turk DC. 1999, New York: Guilford Press, 3-17.

103.

Turk D, Okifuji A: Psychological factors in chronic pain: evolution and revolution. J Consult Clin Psychol. 2002, 70: 678-690. 10.1037/0022-006X.70.3.678.PubMed

104.

Blyth FM, March LM, Brnabic AJ, Jorm LR, Williamson M, Cousins M: Chronic pain in Australia: a prevalence study. Pain. 2001, 89: 127-134. 10.1016/S0304-3959(00)00355-9.PubMed

105.

Morris DB: Sociocultural and religious meanings of pain. Psychosocial factors in pain Critical perspectives. Edited by: Gatchel RJ, Turk DC. 1999, New York: Guilford Press, 118-131.

106.

Williams DA, Thorn BE: An empirical assessment of pain beliefs. Pain. 1989, 36: 351-358. 10.1016/0304-3959(89)90095-X.PubMed

107.

Hoogendoorn W, van Poppel M, Bongers P, Koes B, Bouter L: Systematic review of psychosocial factors at work and private life as risk factors for back pain. Spine. 2000, 25: 2114-2125. 10.1097/00007632-200008150-00017.PubMed

108.

Bongers P, Kremer A, ter Laak J: Are psychosocial factors, risk factors for symptoms and signs of the shoulder, elbow, or hand/wrist?: a review of the epidemiological literature. Am J Ind Med. 2002, 41: 315-342. 10.1002/ajim.10050.PubMed

109.

Herda C, Siegeris K, Basler H: The pain beliefs and perceptions inventory: Further evidence for a 4-factor structure. Pain. 1994, 57:

110.

Turner J, Jensen M, Romano J: Do beliefs, coping, and catastrophizing independently predict functioning in patients with chronic pain?. Pain. 2000, 85:

111.

Stroud M, Thorn B, Jensen M, Boothby J, Rohay J, Bernier M: The relation between pain beliefs, negative thoughts, and psychosocial functioning in chronic-pain patients. Pain. 2000, 84: 347-352. 10.1016/S0304-3959(99)00226-2.PubMed

112.

Nahit E, Hunt I, Lunt M, Dunn G, Silman A, Macfarlane G: Effects of psychosocial and individual psychological factors on the onset of musculoskeletal pain: common and site-specific effects. Ann Rheum Dis. 2003, 2: 755-760. 10.1136/ard.62.8.755.

113.

Hartvigsen J, Lings S, Leboeuf-Yde C, Bakketeig L: Psychosocial factors at work in relation to low back pain and consequences of low back pain; a systematic, critical review of prospective cohort studies. Occup Environ Med. 2004, 61: e2-PubMedPubMedCentral

114.

Chesterton L, Barlas P, Foster N, Baxter G, Wright C: Gender differences in pressure pain threshold in healthy humans. Pain. 2003, 101: 259-266. 10.1016/S0304-3959(02)00330-5.PubMed

115.

Wise E, Price D, Myers C, Heft M, Robinson M: Gender role expectations of pain: relationship to experimental pain perception. Pain. 2002, 96: 335-342. 10.1016/S0304-3959(01)00473-0.PubMedPubMedCentral

116.

Ramos J: Placebo effect and pain: brain bases. Neurologia. 2007, 22: 99-105.PubMed

117.

Benedetti F, Mayberg H, Wager T, Stohler C, Zubieta J: Neurobiological mechanisms of the placebo effect. J Neurosci. 2005, 25: 10390-10402. 10.1523/JNEUROSCI.3458-05.2005.PubMed

118.

Kuehn BM: Pain studies illuminate the placebo effect. JAMA. 2005, 294 (14): 1750-1701. 10.1001/jama.294.14.1750.PubMed

119.

Haour F: Mechanisms of placebo effect and of conditioning: neurobiological data in human and animals. Med Sci (Paris). 2005, 21: 315-319.

120.

Boussageon R, Gueyffier F, Moreau A, Boussageon V: The difficulty of measurement of placebo effect. Therapie. 2006, 61: 185-190.PubMed

121.

McCarney R, Warner J, Iliffe S, van Haselen R, Griffin M, Fisher P: The Hawthorne Effect: a randomised, controlled trial. BMC Med Res Methodol. 2007, 7:

122.

Hunsley J, Westmacott R: Interpreting the magnitude of the placebo effect: mountain or Molehill?. J Clin Psychol. 2007, 63: 391-399. 10.1002/jclp.20352.PubMed

123.

Oh V: The placebo effect: can we use it better?. BMJ. 1994, 309 (6947): 69-70.PubMedPubMedCentral

124.

de la Fuente-Fernandez R, Stoessl A: The biochemical bases of the placebo effect. Sci Eng Ethics. 2004, 10: 143-150. 10.1007/s11948-004-0071-z.PubMed

125.

Tiller WA: Human psychophysiology, macroscopic information entanglement, and the placebo effect. J Altern Complement Med. 2006, 12: 1015-1027. 10.1089/acm.2006.12.1015.PubMed

126.

Hróbjartsson A, Gøtzsche P: Placebo interventions for all clinical conditions. Cochrane Database of Sys Rev. 2004, CD003974-

127.

Crosbie J, Burns J: Predicting outcomes in the orthotic management of painful, idiopathic pes cavus. Clin J Sport Med. 2007, 17: 337-342.PubMed

128.

Landorf K, Keenan A, Herbert R: Effectiveness of foot orthoses to treat plantar fasciitis: a randomized trial. Archives of Internal Medicine. 2006, 166: 1305-1310. 10.1001/archinte.166.12.1305.PubMed

129.

Colloca L, Benedetti F: Placebos and painkillers: is mind as real as matter?. Nature Reviews Neuroscience. 2005, 6: 545-552. 10.1038/nrn1705.PubMed

Title: Understanding the nature and mechanism of foot pain
Authors: Fiona Hawke
Joshua Burns
Publication date: 01-12-2009
Publisher: BioMed Central
Published in: Journal of Foot and Ankle Research / Issue 1/2009
Electronic ISSN: 1757-1146
DOI: https://doi.org/10.1186/1757-1146-2-1

ACC 2024 Congress

Springer Medicine

Understanding the nature and mechanism of foot pain

Abstract

ACC 2024 Congress

Springer Medicine

Abstract

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