Published in:
Open Access
01-12-2012 | Meeting abstract
T-cell immunodeficiency and reconstruction based on TCR rearrangement analysis in hematological malignancy: update from 2011 ASH annual meeting
Author:
Yangqiu Li
Published in:
Journal of Hematology & Oncology
|
Special Issue 1/2012
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Excerpt
Poor cellular immune function may relate to carcinogenic processes and to worse prognosis in solid tumor patients as well as in leukemia. Moreover, the progression of tumor might further induce the cellular immune suppression. Therefore, a set of molecular immunological techniques to analyze and monitor the changes of host T-cell immune status is needed, which can fully characterize the feature of T-cell immunodeficiency in different malignancies, providing information and direction for immune reconstruction, in particular for enhancement the specific anti-tumor immune function. …