Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2014

Open Access 01-12-2014 | Case report

Hyperbaric oxygen therapy in combination with systemic treatment of sickle cell disease presenting as central retinal artery occlusion: a case report

Published in: Journal of Medical Case Reports | Issue 1/2014

Login to get access

Abstract

Introduction

We describe hyperbaric oxygen therapy for the treatment of central retinal artery occlusion in a young adult with sickle cell disease.

Case presentation

A 25-year-old Turkish man with a history of sickle cell disease developed sudden painless loss of vision in the left eye and was hospitalized for diagnosis and treatment. Central retinal artery occlusion was diagnosed with retinal whitening, cherry red spot, and delayed arteriovenous transit on fluorescein angiography. He underwent exchange transfusion and hyperbaric oxygen therapy. In the following three months, his visual acuity improved to 20/30.

Conclusions

In this present case with sickle cell disease, the visual acuity improved with hyperbaric oxygen therapy in addition to systemic therapy. The result of our case suggests that hyperbaric oxygen therapy may be beneficial in the treatment of central retinal artery occlusion.
Appendix
Available only for authorised users
Literature
1.
go back to reference Brown GC, Magargal LE, Shields JA, Goldberg RE, Walsh PN: Retinal arterial obstruction in children and young adults. Ophthalmology. 1981, 88: 18-25. 10.1016/S0161-6420(81)35080-5.CrossRefPubMed Brown GC, Magargal LE, Shields JA, Goldberg RE, Walsh PN: Retinal arterial obstruction in children and young adults. Ophthalmology. 1981, 88: 18-25. 10.1016/S0161-6420(81)35080-5.CrossRefPubMed
2.
go back to reference Yanoff M, Duker JS: Ophthalmology. 2004, St. Louis: Mosby, Inc, 1678- Yanoff M, Duker JS: Ophthalmology. 2004, St. Louis: Mosby, Inc, 1678-
3.
go back to reference Downes SM, Hambleton IR, Chuang EL, Lois N, Serjeant GR, Bird AC: Incidence and natural history of proliferative sickle cell retinopathy: observations from a cohort study. Ophthalmology. 2005, 112: 1869-1875. 10.1016/j.ophtha.2005.05.026.CrossRefPubMed Downes SM, Hambleton IR, Chuang EL, Lois N, Serjeant GR, Bird AC: Incidence and natural history of proliferative sickle cell retinopathy: observations from a cohort study. Ophthalmology. 2005, 112: 1869-1875. 10.1016/j.ophtha.2005.05.026.CrossRefPubMed
4.
go back to reference Clarkson JG: The ocular manifestations of sickle-cell disease: a prevalence and natural history study. Trans Am Ophthalmol Soc. 1992, 90: 481-504.PubMedPubMedCentral Clarkson JG: The ocular manifestations of sickle-cell disease: a prevalence and natural history study. Trans Am Ophthalmol Soc. 1992, 90: 481-504.PubMedPubMedCentral
5.
go back to reference Sanghvi C, Laude A, Smith A, Dodd CL: Superior macular sparing in central retinal artery occlusion due to sickle cell anaemia. Eye (Lond). 2004, 18: 442-443. 10.1038/sj.eye.6700684.CrossRef Sanghvi C, Laude A, Smith A, Dodd CL: Superior macular sparing in central retinal artery occlusion due to sickle cell anaemia. Eye (Lond). 2004, 18: 442-443. 10.1038/sj.eye.6700684.CrossRef
6.
go back to reference Liem RI, Calamaras DM, Chhabra MS, Files B, Minniti CP, Thompson AA: Sudden-onset blindness in sickle cell disease due to retinal artery occlusion. Pediatr Blood Cancer. 2008, 50: 624-627. 10.1002/pbc.21152.CrossRefPubMed Liem RI, Calamaras DM, Chhabra MS, Files B, Minniti CP, Thompson AA: Sudden-onset blindness in sickle cell disease due to retinal artery occlusion. Pediatr Blood Cancer. 2008, 50: 624-627. 10.1002/pbc.21152.CrossRefPubMed
7.
go back to reference Al-Abdulla NA, Haddock TA, Kerrison JB, Goldberg MF: Sickle cell disease presenting with extensive peri-macular arteriolar occlusions in a nine-year-old boy. Am J Ophthalmol. 2001, 131: 275-276. 10.1016/S0002-9394(00)00778-9.CrossRefPubMed Al-Abdulla NA, Haddock TA, Kerrison JB, Goldberg MF: Sickle cell disease presenting with extensive peri-macular arteriolar occlusions in a nine-year-old boy. Am J Ophthalmol. 2001, 131: 275-276. 10.1016/S0002-9394(00)00778-9.CrossRefPubMed
8.
go back to reference Beiran I, Goldenberg I, Adir Y, Tamir A, Shupak A, Miller B: Early hyperbaric oxygen therapy for retinal artery occlusion. Eur J Ophthalmol. 2001, 11: 345-350.PubMed Beiran I, Goldenberg I, Adir Y, Tamir A, Shupak A, Miller B: Early hyperbaric oxygen therapy for retinal artery occlusion. Eur J Ophthalmol. 2001, 11: 345-350.PubMed
9.
go back to reference Weinberger AW, Siekmann UP, Wolf S, Rossaint R, Kirchhof B, Schrage NF: Treatment of acute central retinal artery occlusion (CRAO) by hyperbaric oxygenation therapy (HBO)-Pilot study with 21 patients. Klin Monbl Augenheilkd. 2002, 219: 728-734. 10.1055/s-2002-35687.CrossRefPubMed Weinberger AW, Siekmann UP, Wolf S, Rossaint R, Kirchhof B, Schrage NF: Treatment of acute central retinal artery occlusion (CRAO) by hyperbaric oxygenation therapy (HBO)-Pilot study with 21 patients. Klin Monbl Augenheilkd. 2002, 219: 728-734. 10.1055/s-2002-35687.CrossRefPubMed
10.
go back to reference Oguz H, Sobaci G: The use of hyperbaric oxygen therapy in ophthalmology. Surv Ophthalmol. 2008, 53: 112-120. 10.1016/j.survophthal.2007.12.002.CrossRefPubMed Oguz H, Sobaci G: The use of hyperbaric oxygen therapy in ophthalmology. Surv Ophthalmol. 2008, 53: 112-120. 10.1016/j.survophthal.2007.12.002.CrossRefPubMed
11.
go back to reference Aisenbrey S, Krott R, Heller R, Krauss D, Rössler G, Heimann K: Hyperbaric oxygen therapy in retinal artery occlusion. Ophthalmologe. 2000, 97: 461-467. 10.1007/s003470070075.CrossRefPubMed Aisenbrey S, Krott R, Heller R, Krauss D, Rössler G, Heimann K: Hyperbaric oxygen therapy in retinal artery occlusion. Ophthalmologe. 2000, 97: 461-467. 10.1007/s003470070075.CrossRefPubMed
12.
go back to reference Wallyn CR, Jampol LM, Goldberg MF, Zanetti CL: The use of hyperbaric oxygen therapy in the treatment of sickle cell hyphema. Invest Ophthalmol Vis Sci. 1985, 26: 1155-1158.PubMed Wallyn CR, Jampol LM, Goldberg MF, Zanetti CL: The use of hyperbaric oxygen therapy in the treatment of sickle cell hyphema. Invest Ophthalmol Vis Sci. 1985, 26: 1155-1158.PubMed
13.
go back to reference Menzel-Severing J, Siekmann U, Weinberger A, Roessler G, Walter P, Mazinani B: Early hyperbaric oxygen treatment for nonarteritic central retinal artery obstruction. Am J Ophthalmol. 2012, 153: 454-459. 10.1016/j.ajo.2011.08.009.CrossRefPubMed Menzel-Severing J, Siekmann U, Weinberger A, Roessler G, Walter P, Mazinani B: Early hyperbaric oxygen treatment for nonarteritic central retinal artery obstruction. Am J Ophthalmol. 2012, 153: 454-459. 10.1016/j.ajo.2011.08.009.CrossRefPubMed
Metadata
Title
Hyperbaric oxygen therapy in combination with systemic treatment of sickle cell disease presenting as central retinal artery occlusion: a case report
Publication date
01-12-2014
Published in
Journal of Medical Case Reports / Issue 1/2014
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-8-370

Other articles of this Issue 1/2014

Journal of Medical Case Reports 1/2014 Go to the issue