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Published in: Journal of Medical Case Reports 1/2014

Open Access 01-12-2014 | Case report

Rare and massive odontogenic parakeratotic cyst treated by endoscopic sinus surgery: a case report

Authors: Dario Marcotullio, Giannicola Iannella, Melissa Zelli, Caterina Marinelli, Giuseppe Magliulo

Published in: Journal of Medical Case Reports | Issue 1/2014

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Abstract

Introduction

Keratocystic odontogenic tumors are benign neoplasms of odontogenic origin with a potential for aggressive and infiltrative behavior. Many different treatments for this type of lesion have been reported. However, no common consensus has emerged to date regarding the most effective therapeutic approach. Cases of maxillary sinus giant keratocystic odontogenic tumors completely excised by enucleation or marsupialization via endoscopic sinus surgery are extremely rare, and, to the best of our knowledge, only one case has been described in the literature since 2005.

Case presentation

We report a case of a 24-year-old Italian man who came to our department with maxillary sinus region swelling, pain and left nasal obstruction. A massive keratocystic odontogenic tumor involving the right maxillary sinus and causing focal erosions of the bony walls was diagnosed. The keratocystic odontogenic tumor was removed as much as possible by a transnasal approach using endoscopic sinus surgery, which produced optimal surgical and prognostic outcomes. Follow-up is reported for an 8-year period.

Conclusion

Conservative management in this case demonstrated good therapeutic efficacy with a low risk of recurrence. For injuries involving the maxillary sinus, the possibility of decompression or marsupialization by endoscopic sinus surgery should always be considered because it demonstrated the potential to lead to excellent results even after 8 years of follow-up in our patient. To our knowledge, no case report has described follow-up longer than 8 years for a maxillary sinus keratocystic odontogenic tumor treated with endoscopic sinus surgery.
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Literature
1.
go back to reference Mendes RA, Carvalho JF, van der Waal I: Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol. 2010, 46: 219-225. 10.1016/j.oraloncology.2010.01.012.CrossRefPubMed Mendes RA, Carvalho JF, van der Waal I: Characterization and management of the keratocystic odontogenic tumor in relation to its histopathological and biological features. Oral Oncol. 2010, 46: 219-225. 10.1016/j.oraloncology.2010.01.012.CrossRefPubMed
2.
go back to reference Kaczmarzyk T, Mojsa I, Stypulkowska J: A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities. Int J Oral Maxillofac Surg. 2012, 41: 756-767. 10.1016/j.ijom.2012.02.008.CrossRefPubMed Kaczmarzyk T, Mojsa I, Stypulkowska J: A systematic review of the recurrence rate for keratocystic odontogenic tumour in relation to treatment modalities. Int J Oral Maxillofac Surg. 2012, 41: 756-767. 10.1016/j.ijom.2012.02.008.CrossRefPubMed
3.
go back to reference Ohki M: Transnasal marsupialization using endoscopic sinus surgery for treatment of keratocystic odontogenic tumor in maxillary sinus. Case Rep Otolaryngol. 2012, 2012: 281402-PubMedPubMedCentral Ohki M: Transnasal marsupialization using endoscopic sinus surgery for treatment of keratocystic odontogenic tumor in maxillary sinus. Case Rep Otolaryngol. 2012, 2012: 281402-PubMedPubMedCentral
4.
go back to reference Philipsen HP: Om keratocyster (kolesteatom) i kæberne. Tandlaegebladet. 1956, 60: 963-981. Philipsen HP: Om keratocyster (kolesteatom) i kæberne. Tandlaegebladet. 1956, 60: 963-981.
5.
go back to reference Philipsen HP, Reichart PA: Classification of odontogenic tumours: a historical review. J Oral Pathol Med. 2006, 35: 525-529. 10.1111/j.1600-0714.2006.00470.x.CrossRefPubMed Philipsen HP, Reichart PA: Classification of odontogenic tumours: a historical review. J Oral Pathol Med. 2006, 35: 525-529. 10.1111/j.1600-0714.2006.00470.x.CrossRefPubMed
7.
go back to reference Kuroyanagi N, Sakuma H, Miyabe S, Machida J, Kaetsu A, Yokoi M, Maeda H, Warnakulasuriya S, Nagao T, Shimozato K: Prognostic factors for keratocystic odontogenic tumor (odontogenic keratocyst): analysis of clinico-pathologic and immunohistochemical findings in cysts treated by enucleation. J Oral Pathol Med. 2009, 38: 386-392. 10.1111/j.1600-0714.2008.00729.x.CrossRefPubMed Kuroyanagi N, Sakuma H, Miyabe S, Machida J, Kaetsu A, Yokoi M, Maeda H, Warnakulasuriya S, Nagao T, Shimozato K: Prognostic factors for keratocystic odontogenic tumor (odontogenic keratocyst): analysis of clinico-pathologic and immunohistochemical findings in cysts treated by enucleation. J Oral Pathol Med. 2009, 38: 386-392. 10.1111/j.1600-0714.2008.00729.x.CrossRefPubMed
8.
go back to reference Simiyu BN, Butt F, Dimba EA, Wagaiyu EG, Awange DO, Guthua SW, Slootweg PJ: Keratocystic odontogenic tumours of the jaws and associated pathologies: a 10-year clinicopathologic audit in a referral teaching hospital in Kenya. J Craniomaxillofac Surg. 2013, 41: 230-234. 10.1016/j.jcms.2012.09.006.CrossRefPubMed Simiyu BN, Butt F, Dimba EA, Wagaiyu EG, Awange DO, Guthua SW, Slootweg PJ: Keratocystic odontogenic tumours of the jaws and associated pathologies: a 10-year clinicopathologic audit in a referral teaching hospital in Kenya. J Craniomaxillofac Surg. 2013, 41: 230-234. 10.1016/j.jcms.2012.09.006.CrossRefPubMed
9.
go back to reference Maurette PE, Jorge J, de Moraes M: Conservative treatment protocol of odontogenic keratocyst: a preliminary study. J Oral Maxillofac Surg. 2006, 64: 379-383. 10.1016/j.joms.2005.11.007.CrossRefPubMed Maurette PE, Jorge J, de Moraes M: Conservative treatment protocol of odontogenic keratocyst: a preliminary study. J Oral Maxillofac Surg. 2006, 64: 379-383. 10.1016/j.joms.2005.11.007.CrossRefPubMed
10.
go back to reference Caixeta Guimarães A, Dutra de Cassia Ferreira Santos M, Machado de Carvalho G, Takahiro Chone C, Nizam Pfeilsticker L: Giant keratocystic odontogenic tumor: three cases and literature review. Iran J Otorhinolaryngol. 2013, 25: 245-252.PubMedPubMedCentral Caixeta Guimarães A, Dutra de Cassia Ferreira Santos M, Machado de Carvalho G, Takahiro Chone C, Nizam Pfeilsticker L: Giant keratocystic odontogenic tumor: three cases and literature review. Iran J Otorhinolaryngol. 2013, 25: 245-252.PubMedPubMedCentral
11.
go back to reference Woolgar JA, Rippin JW, Browne RM: A comparative study of the clinical and histological features of recurrent and non-recurrent odontogenic keratocysts. J Oral Pathol. 1987, 16: 124-128. 10.1111/j.1600-0714.1987.tb01478.x.CrossRefPubMed Woolgar JA, Rippin JW, Browne RM: A comparative study of the clinical and histological features of recurrent and non-recurrent odontogenic keratocysts. J Oral Pathol. 1987, 16: 124-128. 10.1111/j.1600-0714.1987.tb01478.x.CrossRefPubMed
12.
go back to reference Marker P, Brøndum N, Clausen PP, Bastian HL: Treatment of large odontogenic keratocysts by decompression and later cystectomy: a long-term follow-up and a histologic study of 23 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996, 82: 122-131. 10.1016/S1079-2104(96)80214-9.CrossRefPubMed Marker P, Brøndum N, Clausen PP, Bastian HL: Treatment of large odontogenic keratocysts by decompression and later cystectomy: a long-term follow-up and a histologic study of 23 cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1996, 82: 122-131. 10.1016/S1079-2104(96)80214-9.CrossRefPubMed
13.
go back to reference Partsch C: Uber Kiefercysten. Dtsch Mschr Zahnheilkd. 1892, 10: 271- Partsch C: Uber Kiefercysten. Dtsch Mschr Zahnheilkd. 1892, 10: 271-
14.
go back to reference Partsch C: Zur Behandlung der Kieferzysten. Dtsch Mschr Zahnheilkd. 1910, 28: 252- Partsch C: Zur Behandlung der Kieferzysten. Dtsch Mschr Zahnheilkd. 1910, 28: 252-
15.
go back to reference Pogrel MA, Jordan RC: Marsupialization as a definitive treatment for the odontogenic keratocyst. J Oral Maxillofac Surg. 2004, 62: 651-655. 10.1016/j.joms.2003.08.029.CrossRefPubMed Pogrel MA, Jordan RC: Marsupialization as a definitive treatment for the odontogenic keratocyst. J Oral Maxillofac Surg. 2004, 62: 651-655. 10.1016/j.joms.2003.08.029.CrossRefPubMed
Metadata
Title
Rare and massive odontogenic parakeratotic cyst treated by endoscopic sinus surgery: a case report
Authors
Dario Marcotullio
Giannicola Iannella
Melissa Zelli
Caterina Marinelli
Giuseppe Magliulo
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2014
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-8-293

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