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Open Access 01-12-2013 | Case report

Human cord blood-derived mononuclear cell transplantation for viral encephalitis-associated cognitive impairment: a case report

Published in: Journal of Medical Case Reports | Issue 1/2013

Abstract

Introduction

Herpes simplex virus is the most common cause of sporadic viral encephalitis. Cognitive impairments persist in most patients who survive herpes simplex virus-caused encephalitis after undergoing currently available treatments. This is the first report on the development of human cord blood-derived mononuclear cell transplantation as a new treatment intervention to improve the prognosis of sequelae of viral encephalitis.

Case presentation

An 11-year-old Han Chinese boy developed sequelae of viral encephalitis with cognitive, mental and motor impairments in the 8 months following routine treatments. Since receiving allogeneic cord blood-derived mononuclear cell transplantation combined with comprehensive rehabilitation therapies 7 years ago, the patient’s health has significantly improved and remained stable.

Conclusions

Human cord blood-derived mononuclear cell transplantation may be a potential therapeutic strategy for treating the neuropsychiatric and neurobehavioral sequelae of viral encephalitis.

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Title: Human cord blood-derived mononuclear cell transplantation for viral encephalitis-associated cognitive impairment: a case report
Publication date: 01-12-2013
Published in: Journal of Medical Case Reports / Issue 1/2013
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-7-181

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Human cord blood-derived mononuclear cell transplantation for viral encephalitis-associated cognitive impairment: a case report

Abstract

Introduction

Case presentation

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusions

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