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Published in: Journal of Medical Case Reports 1/2012

Open Access 01-12-2012 | Case report

Hypertriglyceridemia as a possible cause of coma: a case report

Authors: Ryota Inokuchi, Akinori Matsumoto, Ryuta Azihara, Hajime Sato, Yoshibumi Kumada, Hideyuki Yokoyama, Megumi Okada, Tokiya Ishida, Kensuke Nakamura, Susumu Nakajima, Naoki Yahagi, Kazuaki Shinohara

Published in: Journal of Medical Case Reports | Issue 1/2012

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Abstract

Introduction

Many studies suggest that elevated triglyceride levels are associated with increased long-term risk of stroke, including transient ischemic attacks. In addition, elevated triglyceride levels independently contribute to plasma viscosity and decreased blood flow. However, no consensus has been reached regarding the significance of hypertriglyceridemia as an independent risk factor for ischemic stroke.

Case presentation

We report the case of a patient admitted to our hospital for sudden onset of coma. Laboratory test results revealed he had high blood glucose (28.2mmol/L), high glycated hemoglobin (11.4 percent), considerably high serum triglyceride levels (171.5mmol/L; type V hyperlipoproteinemia), and high plasma viscosity (1.90mPa/s) with normal β-hydroxybutyric acid levels. His triglyceride levels decreased after administering intravenous fluids. Our patient’s consciousness level improved gradually over three days. All serum lipid levels decreased seven days after admission.

Conclusions

The findings in our patient’s case are likely explained by triglyceride-mediated hyperviscosity causing a transient ischemic attack. In the present report we suggest that when several tests do not reveal the cause of stroke-like symptoms, measurement of plasma viscosity may be informative.
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Metadata
Title
Hypertriglyceridemia as a possible cause of coma: a case report
Authors
Ryota Inokuchi
Akinori Matsumoto
Ryuta Azihara
Hajime Sato
Yoshibumi Kumada
Hideyuki Yokoyama
Megumi Okada
Tokiya Ishida
Kensuke Nakamura
Susumu Nakajima
Naoki Yahagi
Kazuaki Shinohara
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2012
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-6-412

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