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Published in: Journal of Medical Case Reports 1/2012

Open Access 01-12-2012 | Case report

Pure sensory syndromes and post-stroke pain secondary to bilateral thalamic lacunar infarcts: a case report

Authors: Karl B Alstadhaug, Jan F Prytz

Published in: Journal of Medical Case Reports | Issue 1/2012

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Abstract

Introduction

Patients often complain about sensory symptoms that appear to the doctor as harmless, and reassurances are often given. Sensory strokes may easily be ignored.

Case presentation

A 48-year-old Caucasian woman with insulin-dependent diabetes and hyperlipidemia experienced symptoms that progressed within hours to a complete left-sided hemisensory syndrome. This was caused by a lacunar infarct in the ventral posterior tier nuclei of the right thalamus. A few days later she gradually developed an almost identical, but incomplete hemisensory syndrome on the opposite side caused by a corresponding lacune in the left thalamus. Severe persistent and paroxysmal pain on both sides of the body became disabling.

Conclusion

Small strokes only affecting the somatosensory system should not be underestimated. Neuropathic pain may result. Probably unique in the present case is the demonstration of bilateral thalamic pain secondary to two almost identical thalamic infarcts. Small vessel disease (microatheroma or lipohyalinosis) was the most likely cause of the lacunes. One can only speculate if there was an occlusion in two separate thalamic perforators, or in a single dominant artery supplying the bilateral thalami.
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Literature
1.
go back to reference Fisher CM: Pure sensory stroke involving face, arm and leg. Neurology (Minneap). 1965, 15: 76-10.1212/WNL.15.1.76.CrossRef Fisher CM: Pure sensory stroke involving face, arm and leg. Neurology (Minneap). 1965, 15: 76-10.1212/WNL.15.1.76.CrossRef
2.
go back to reference Kim JS: Pure sensory stroke. Clinical-radiological correlates of 21 cases. Stroke. 1992, 23: 983-987. 10.1161/01.STR.23.7.983.CrossRefPubMed Kim JS: Pure sensory stroke. Clinical-radiological correlates of 21 cases. Stroke. 1992, 23: 983-987. 10.1161/01.STR.23.7.983.CrossRefPubMed
3.
go back to reference Fisher CM: Pure sensory stroke and allied conditions. Stroke. 1982, 13: 434-10.1161/01.STR.13.4.434.CrossRefPubMed Fisher CM: Pure sensory stroke and allied conditions. Stroke. 1982, 13: 434-10.1161/01.STR.13.4.434.CrossRefPubMed
4.
go back to reference Kim JH, Greenspan JD, Coghill RC, JD , Ohara S, Lenz FA: Lesions limited to the human thalamic principal sensory nucleus (ventral caudal) are associated with loss of cold sensations and central pain. J Neurosci. 2007, 27: 4995-5004. 10.1523/JNEUROSCI.0716-07.2007.CrossRefPubMed Kim JH, Greenspan JD, Coghill RC, JD , Ohara S, Lenz FA: Lesions limited to the human thalamic principal sensory nucleus (ventral caudal) are associated with loss of cold sensations and central pain. J Neurosci. 2007, 27: 4995-5004. 10.1523/JNEUROSCI.0716-07.2007.CrossRefPubMed
5.
go back to reference Paciaroni M, Bogousslavsky J: Pure sensory syndromes in thalamic stroke. Eur Neurol. 1998, 39: 211-217. 10.1159/000007936.CrossRefPubMed Paciaroni M, Bogousslavsky J: Pure sensory syndromes in thalamic stroke. Eur Neurol. 1998, 39: 211-217. 10.1159/000007936.CrossRefPubMed
6.
go back to reference Déjerine J, Roussy G: Le syndrome thalamique. Rev Neurol (Paris). 1906, 14: 521-532. Déjerine J, Roussy G: Le syndrome thalamique. Rev Neurol (Paris). 1906, 14: 521-532.
7.
go back to reference Bennett MI, Attal N, Backonja MM, Baron R, Bouhassira D, Freynhagen R, Scholz J, Tölle TR, Wittchen HU, Jensen TS: Using screening tools to identify neuropathic pain. Pain. 2007, 127: 199-203. 10.1016/j.pain.2006.10.034.CrossRefPubMed Bennett MI, Attal N, Backonja MM, Baron R, Bouhassira D, Freynhagen R, Scholz J, Tölle TR, Wittchen HU, Jensen TS: Using screening tools to identify neuropathic pain. Pain. 2007, 127: 199-203. 10.1016/j.pain.2006.10.034.CrossRefPubMed
8.
go back to reference MacGowan DJ, Janal MN, Clark WC, Wharton RN, Lazar RM, Sacco RL, Mohr JP: Central poststroke pain and Wallenberg’s lateral medullary infarction: frequency, character, and determinants in 63 patients. Neurology. 1997, 49: 120-155. 10.1212/WNL.49.1.120.CrossRefPubMed MacGowan DJ, Janal MN, Clark WC, Wharton RN, Lazar RM, Sacco RL, Mohr JP: Central poststroke pain and Wallenberg’s lateral medullary infarction: frequency, character, and determinants in 63 patients. Neurology. 1997, 49: 120-155. 10.1212/WNL.49.1.120.CrossRefPubMed
9.
go back to reference Martí-Vilalta JL, Arboix A, Mohr JP: Microangiopathies (Lacunes). Stroke: Pathophysiology, Diagnosis, and Management. Edited by: Mohr JP. 2011, Elsevier and Saunders, Philadelphia, 494-497. 5 Martí-Vilalta JL, Arboix A, Mohr JP: Microangiopathies (Lacunes). Stroke: Pathophysiology, Diagnosis, and Management. Edited by: Mohr JP. 2011, Elsevier and Saunders, Philadelphia, 494-497. 5
10.
go back to reference Smith AB, Smirniotopoulos JG, Rushing EJ, Goldstein SJ: Bilateral thalamic lesions. Am J Radiol. 2009, 192: W53-W62. Smith AB, Smirniotopoulos JG, Rushing EJ, Goldstein SJ: Bilateral thalamic lesions. Am J Radiol. 2009, 192: W53-W62.
11.
go back to reference Lazzaro NA, Wright B, Castillo M, Fischbein NJ, Glastonbury CM, Hildenbrand PG, Wiggins RH, Quigley EP, Osborn AG: Artery of percheron infarction: imaging patterns and clinical spectrum. Am J Neuroradiol. 2010, 31: 1283-1289. 10.3174/ajnr.A2044.CrossRefPubMed Lazzaro NA, Wright B, Castillo M, Fischbein NJ, Glastonbury CM, Hildenbrand PG, Wiggins RH, Quigley EP, Osborn AG: Artery of percheron infarction: imaging patterns and clinical spectrum. Am J Neuroradiol. 2010, 31: 1283-1289. 10.3174/ajnr.A2044.CrossRefPubMed
12.
go back to reference Cordery RJ, Rossor MN: Bilateral thalamic pain secondary to bilateral thalamic infarcts relieved by a further unilateral ischaemic episode. Eur J Neurol. 1999, 6: 717-719. 10.1046/j.1468-1331.1999.660717.x.CrossRefPubMed Cordery RJ, Rossor MN: Bilateral thalamic pain secondary to bilateral thalamic infarcts relieved by a further unilateral ischaemic episode. Eur J Neurol. 1999, 6: 717-719. 10.1046/j.1468-1331.1999.660717.x.CrossRefPubMed
13.
go back to reference Schmahmann JD: Vascular syndromes of the thalamus. Stroke. 2003, 34: 2264-2278. 10.1161/01.STR.0000087786.38997.9E.CrossRefPubMed Schmahmann JD: Vascular syndromes of the thalamus. Stroke. 2003, 34: 2264-2278. 10.1161/01.STR.0000087786.38997.9E.CrossRefPubMed
14.
go back to reference Arboix A, García-Plata C, García-Eroles L, Massons J, Comes E, Oliveres M, Targa C: Clinical study of 99 patients with pure sensory stroke. J Neurol. 2005, 252: 156-162. 10.1007/s00415-005-0622-5.CrossRefPubMed Arboix A, García-Plata C, García-Eroles L, Massons J, Comes E, Oliveres M, Targa C: Clinical study of 99 patients with pure sensory stroke. J Neurol. 2005, 252: 156-162. 10.1007/s00415-005-0622-5.CrossRefPubMed
15.
go back to reference Arboix A, Font A, Garro C, García-Eroles L, Comes E, Massons J: Recurrent lacunar infarction following a previous lacunar stroke: a clinical study of 122 patients. J Neurol Neurosurg Psychiatry. 2007, 78: 1392-1394. 10.1136/jnnp.2007.119776.CrossRefPubMedPubMedCentral Arboix A, Font A, Garro C, García-Eroles L, Comes E, Massons J: Recurrent lacunar infarction following a previous lacunar stroke: a clinical study of 122 patients. J Neurol Neurosurg Psychiatry. 2007, 78: 1392-1394. 10.1136/jnnp.2007.119776.CrossRefPubMedPubMedCentral
16.
go back to reference Klit H, Finnerup NB, Jensen TS: Central post-stroke pain: clinical characteristics, pathophysiology, and management. Lancet Neurol. 2009, 8: 857-868. 10.1016/S1474-4422(09)70176-0.CrossRefPubMed Klit H, Finnerup NB, Jensen TS: Central post-stroke pain: clinical characteristics, pathophysiology, and management. Lancet Neurol. 2009, 8: 857-868. 10.1016/S1474-4422(09)70176-0.CrossRefPubMed
18.
go back to reference Naidich TP, Duvernoy HM, Delman BN, Sorensen AG, Spyros SK, Haacke EM, Benner T, Boom WW, Cattin F, Choi PS: Duvernoy’s Atlas of the Human Brain Stem and Cerebellum. 2009, Springer, WienCrossRef Naidich TP, Duvernoy HM, Delman BN, Sorensen AG, Spyros SK, Haacke EM, Benner T, Boom WW, Cattin F, Choi PS: Duvernoy’s Atlas of the Human Brain Stem and Cerebellum. 2009, Springer, WienCrossRef
19.
go back to reference Yamada K, Akazawa K, Yuen S, Goto M, Matsushima S, Takahata A, Nakagawa M, Mineura K, Nishimura T: MR imaging of ventral thalamic nuclei. Am J Neuroradiol. 2010, 31: 732-735. 10.3174/ajnr.A1870.CrossRefPubMed Yamada K, Akazawa K, Yuen S, Goto M, Matsushima S, Takahata A, Nakagawa M, Mineura K, Nishimura T: MR imaging of ventral thalamic nuclei. Am J Neuroradiol. 2010, 31: 732-735. 10.3174/ajnr.A1870.CrossRefPubMed
Metadata
Title
Pure sensory syndromes and post-stroke pain secondary to bilateral thalamic lacunar infarcts: a case report
Authors
Karl B Alstadhaug
Jan F Prytz
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2012
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-6-359

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