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Open Access 01-12-2012 | Case report

Mantle cell lymphoma of the larynx: Primary case report

Authors: Sarah Naciri, Anass A Bennani-Baiti, Meriem Glaoui, Houda Mouzount, Samia Ghanem, Leila Essakali, Mohamed Kzadri, Hassan Errihani

Published in: Journal of Medical Case Reports | Issue 1/2012

Abstract

Introduction

Primary laryngeal lymphomas are exceedingly rare. Only about a hundred cases have been reported. They consist mainly of non-Hodgkin lymphoma, especially of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue. We report the first case of a primary laryngeal mantle cell lymphoma.

Case presentation

We report a case of a primary mantle cell lymphoma of the larynx in a 70-year-old North African non-smoker male. We present a detailed report of his clinical and paraclinical data as well as treatment options.

Conclusions

Mantle cell lymphoma is a very aggressive lymphoma subset associated with poor prognosis. Laryngeal mantle cell lymphoma is exceedingly rare. To the best of our knowledge, this is the first case to ever be reported.

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Horny HP, Kaiserling E: Involvement of the larynx by hemopoietic neoplasms. An investigation of autopsy cases and review of the literature. Pathol Res Pract. 1995, 191 (2): 130-138. 10.1016/S0344-0338(11)80562-5.CrossRefPubMed

Horny HP, Ferlito A, Carbone A: Laryngeal lymphoma derived from mucosa-associated lymphoid tissue. Ann Otol Rhinol Laryngol. 1996, 105 (7): 577-583.CrossRefPubMed

Velders GA, Kluin-Nelemans JC, De Boer CJ, Hermans J, Noordijk EM, Schuuring E, Kramer MH, van Deijk WA, Rahder JB, Kluin PM, van Krieken JH: Mantle-cell lymphoma: a population-based clinical study. J Clin Oncol. 1996, 14 (4): 1269-1274.PubMed

The Non-Hodgkin’s Lymphoma Classification Project: A clinical evaluation of the International Lymphoma Study Group classification of non-Hodgkin’s lymphoma. Blood. 1997, 89 (11): 3909-3918.

Word R, Urquhart AC, Ejercito VS: Primary laryngeal lymphoma: case report. Ear Nose Throat J. 2006, 85 (2): 109-111.PubMed

Markou K, Goudakos J, Constantinidis J, Kostopoulos I, Vital V, Nikolaou A: Primary laryngeal lymphoma: report of 3 cases and review of the literature. Head Neck. 2010, 32 (4): 541-549.PubMed

Siddiqui NA, Branstetter BF, Hamilton BE, Ginsberg LE, Glastonbury CM, Harnsberger HR, Barnes EL, Myers EN: Imaging characteristics of primary laryngeal lymphoma. AJNR Am J Neuroradiol. 2010, 31 (7): 1261-1265. 10.3174/ajnr.A2085.CrossRefPubMed

Cheng CJ, Chen PR, Liu MC, Kuo MS, Hsu YH: Primary malignant lymphoma of mucosa-associated lymphoid tissue of larynx. Otolaryngol Head Neck Surg. 1999, 121 (5): 661-662. 10.1016/S0194-5998(99)70079-3.CrossRefPubMed

Fung EK, Neuhauser TS, Thompson LD: Hodgkin-like transformation of a marginal zone B-cell lymphoma of the larynx. Ann Diagn Pathol. 2002, 6 (1): 61-66. 10.1053/adpa.2002.30611.CrossRefPubMed

10.

Brody J, Advani R: Treatment of mantle cell lymphoma: current approach and future directions. Crit Rev Oncol Hematol. 2006, 58 (3): 257-265. 10.1016/j.critrevonc.2005.10.001.CrossRefPubMed

11.

Dreyling M, Weigert O, Hiddemann W: Current treatment standards and future strategies in mantle cell lymphoma. Ann Oncol. 2008, 19 (Suppl 4): iv41-iv44.PubMed

12.

Ghielmini M, Schmitz SF, Cogliatti S, Bertoni F, Waltzer U, Fey MF, Betticher DC, Schefer H, Pichert G, Stahel R, Ketterer N, Bargetzi M, Cerny T, Swiss Group for Clinical Cancer Research: Effect of single-agent rituximab given at the standard schedule or as prolonged treatment in patients with mantle cell lymphoma: a study of the Swiss Group for Clinical Cancer Research (SAKK). J Clin Oncol. 2005, 23 (4): 705-711. 10.1200/JCO.2005.04.164.CrossRefPubMed

13.

Lenz G, Dreyling M, Hoster E, Wörmann B, Dührsen U, Metzner B, Eimermacher H, Neubauer A, Wandt H, Steinhauer H, Martin S, Heidemann E, Aldaoud A, Parwaresch R, Hasford J, Unterhalt M, Hiddemann W: Immunochemotherapy with rituximab and cyclophosphamide, doxorubicin, vincristine, and prednisone significantly improves response and time to treatment failure, but not long-term outcome in patients with previously untreated mantle cell lymphoma: results of a prospective randomized trial of the German Low Grade Lymphoma Study Group (GLSG). J Clin Oncol. 2005, 23 (9): 1984-1992. 10.1200/JCO.2005.08.133.CrossRefPubMed

14.

Howard OM, Gribben JG, Neuberg DS, Grossbard M, Poor C, Janicek MJ, Shipp MA: Rituximab and CHOP induction therapy for newly diagnosed mantle-cell lymphoma: molecular complete responses are not predictive of progression-free survival. J Clin Oncol. 2002, 20 (5): 1288-1294. 10.1200/JCO.20.5.1288.CrossRefPubMed

15.

Mangel J, Buckstein R, Imrie K, Spaner D, Crump M, Tompkins K, Reis M, Perez-Ordonez B, Deodhare S, Romans R, Pennell N, Robinson JB, Hewitt K, Richardson P, Lima A, Pavlin P, Berinstein NL: Immunotherapy with rituximab following high-dose therapy and autologous stem-cell transplantation for mantle cell lymphoma. Semin Oncol. 2002, 29 (1 Suppl 2): 56-69.CrossRefPubMed

16.

Brugger W, Hirsch J, Grunebach F, Repp R, Brossart P, Vogel W, Kopp HG, Manz MG, Bitzer M, Schlimok G, Kaufmann M, Ganser A, Fehnle K, Gramatzki M, Kanz L: Rituximab consolidation after high-dose chemotherapy and autologous blood stem cell transplantation in follicular and mantle cell lymphoma: a prospective, multicenter phase II study. Ann Oncol. 2004, 15 (11): 1691-1698. 10.1093/annonc/mdh425.CrossRefPubMed

17.

Decaudin D, Brousse N, Brice P, Haioun C, Bourhis JH, Morel P, Van Hoof A, Souleau B, Quesnel B, Gisselbrecht C: Efficacy of autologous stem cell transplantation in mantle cell lymphoma: a 3-year follow-up study. Bone Marrow Transplant. 2000, 25 (3): 251-256. 10.1038/sj.bmt.1702135.CrossRefPubMed

18.

Goy A, Bernstein SH, Kahl BS, Djulbegovic B, Robertson MJ, de Vos S, Epner E, Krishnan A, Leonard JP, Lonial S, Nasta S, O'Connor OA, Shi H, Boral AL, Fisher RI: Bortezomib in patients with relapsed or refractory mantle cell lymphoma: updated time-to-event analyses of the multicenter phase 2 PINNACLE study. Ann Oncol. 2009, 20 (3): 520-525.CrossRefPubMed

19.

Kaufmann H, Raderer M, Wohrer S, Püspök A, Bankier A, Zielinski C, Chott A, Drach J: Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma. Blood. 2004, 104 (8): 2269-2271. 10.1182/blood-2004-03-1091.CrossRefPubMed

20.

Kouroukis CT, Belch A, Crump M, Gascoyne RD, Chua NS, Buckstein R, Turner R, Assouline S, Klasa RJ, Walsh W, Powers J, Eisenhauer E: Flavopiridol in untreated or relapsed mantle-cell lymphoma: results of a phase II study of the National Cancer Institute of Canada Clinical Trials Group. J Clin Oncol. 2003, 21 (9): 1740-1745. 10.1200/jco.2003.09.057.CrossRefPubMed

21.

Witzig TE, Geyer SM, Ghobrial I, Inwards DJ, Fonseca R, Kurtin P, Ansell SM, Luyun R, Flynn PJ, Morton RF, Dakhil SR, Gross H, Kaufmann SH: Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma. J Clin Oncol. 2005, 23 (23): 5347-5356. 10.1200/JCO.2005.13.466.CrossRefPubMed

Title: Mantle cell lymphoma of the larynx: Primary case report
Authors: Sarah Naciri
Anass A Bennani-Baiti
Meriem Glaoui
Houda Mouzount
Samia Ghanem
Leila Essakali
Mohamed Kzadri
Hassan Errihani
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2012
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-6-201

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Mantle cell lymphoma of the larynx: Primary case report

Abstract

Introduction

Case presentation

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusions

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