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Journal of Medical Case Reports

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Open Access 01-12-2012 | Case report

Oncogenic osteomalacia associated with mesenchymal tumor in the middle cranial fossa: a case report

Authors: Isao Chokyu, Kenichi Ishibashi, Takeo Goto, Kenji Ohata

Published in: Journal of Medical Case Reports | Issue 1/2012

Abstract

Introduction

Tumor-induced osteomalacia is a paraneoplastic syndrome of hypophosphatemia. Osteomalacia causes multiple bone fractures and severe pain.

Case presentation

We report the case of a 57-year-old Japanese man with tumor-induced osteomalacia associated with a middle cranial fossa bone tumor. The tumor was successfully resected by using a middle fossa epidural approach. His phosphate level recovered to a normal range immediately after the surgery.

Conclusions

It is rare that tumor-induced osteomalacia originates from the middle skull base. This report suggests that, if patients have a clinical and biochemical picture suggestive of tumor-induced osteomalacia, it is crucial to perform a meticulous examination to detect the tumor or the lesion responsible for the tumor. The serum level of fibroblast growth factor 23 is the most reliable marker for evaluating the treatment outcome of tumor-induced osteomalacia.

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Title: Oncogenic osteomalacia associated with mesenchymal tumor in the middle cranial fossa: a case report
Authors: Isao Chokyu
Kenichi Ishibashi
Takeo Goto
Kenji Ohata
Publication date: 01-12-2012
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2012
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-6-181

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Oncogenic osteomalacia associated with mesenchymal tumor in the middle cranial fossa: a case report

Abstract

Introduction

Case presentation

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusions

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