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Published in: Journal of Medical Case Reports 1/2011

Open Access 01-12-2011 | Case report

Synovial sarcoma of the vulva: a case report

Authors: Viren Asher, Gerhard van Schalkwyk, Anish Bali

Published in: Journal of Medical Case Reports | Issue 1/2011

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Abstract

Introduction

Contrary to its name, synovial sarcoma does not arise from the synovial membrane but from multipotent stem cells and can present in any part of the body. Very few cases of vulval synovial sarcoma have been reported in the literature; we report on such a presentation. These tumors can present as painless lumps, which must be completely excised to give the best prognosis. Therefore the diagnosis of synovial sarcoma should always be kept in mind in the management of vulval masses, especially in young patients.

Case presentation

We report the case of a 28-year-old Caucasian woman with synovial sarcoma of the vulva. Complete excision was possible in this case.

Conclusion

We have presented a rare case of synovial sarcoma of the vulva, which can be easily confused with lipoma of the vulva. The management of this tumor requires referral to a cancer centre, with a multidisciplinary approach.
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Literature
1.
go back to reference Enzinger FM, Weiss WS, (eds): Soft tissue tumours. 1995, Louis: Mosby, 3 Enzinger FM, Weiss WS, (eds): Soft tissue tumours. 1995, Louis: Mosby, 3
2.
go back to reference Okcu MF, Munsell M, Treuner J, Mattke A, Pappo A, Cain A, Ferrari A, Casanova M, Ozkan A, Raney B: Synovial sarcoma of childhood and adolescence: a multicenter, multivariate analysis of outcome. J Clin Oncol. 2003, 21 (8): 1602-1611. 10.1200/JCO.2003.07.008.CrossRefPubMed Okcu MF, Munsell M, Treuner J, Mattke A, Pappo A, Cain A, Ferrari A, Casanova M, Ozkan A, Raney B: Synovial sarcoma of childhood and adolescence: a multicenter, multivariate analysis of outcome. J Clin Oncol. 2003, 21 (8): 1602-1611. 10.1200/JCO.2003.07.008.CrossRefPubMed
3.
4.
go back to reference Smith S, Reeves BR, Wong L, Fisher C: A consistent chromosome translocation in synovial sarcoma. Cancer Genet Cytogenet. 1987, 26 (1): 179-180. 10.1016/0165-4608(87)90147-6.CrossRefPubMed Smith S, Reeves BR, Wong L, Fisher C: A consistent chromosome translocation in synovial sarcoma. Cancer Genet Cytogenet. 1987, 26 (1): 179-180. 10.1016/0165-4608(87)90147-6.CrossRefPubMed
5.
go back to reference Holloway CL, Russell AH, Muto M, Albert M, Viswanathan AN: Synovial cell sarcoma of the vulva: multimodality treatment incorporating preoperative external-beam radiation, hemivulvectomy, flap reconstruction, interstitial brachytherapy, and chemotherapy. Gynecol Oncol. 2007, 104 (1): 253-256. 10.1016/j.ygyno.2006.09.018.CrossRefPubMed Holloway CL, Russell AH, Muto M, Albert M, Viswanathan AN: Synovial cell sarcoma of the vulva: multimodality treatment incorporating preoperative external-beam radiation, hemivulvectomy, flap reconstruction, interstitial brachytherapy, and chemotherapy. Gynecol Oncol. 2007, 104 (1): 253-256. 10.1016/j.ygyno.2006.09.018.CrossRefPubMed
6.
go back to reference Coffin CM: Synovial based tumours and synovial sarcoma. Pediatric soft tissue tumors: a clinical pathological and therapeutic approach. Edited by: Coffin CM, O'Shea PA, Dehner LP. 1997, Baltimore: Williams and Wilkins, 295-310. Coffin CM: Synovial based tumours and synovial sarcoma. Pediatric soft tissue tumors: a clinical pathological and therapeutic approach. Edited by: Coffin CM, O'Shea PA, Dehner LP. 1997, Baltimore: Williams and Wilkins, 295-310.
7.
go back to reference Morton MJ, Berquist TH, McLeod RA, Unni KK, Sim FH: MR imaging of synovial sarcoma. AJR Am J Roentgenol. 1991, 156 (2): 337-340.CrossRefPubMed Morton MJ, Berquist TH, McLeod RA, Unni KK, Sim FH: MR imaging of synovial sarcoma. AJR Am J Roentgenol. 1991, 156 (2): 337-340.CrossRefPubMed
8.
go back to reference Andrassy RJ, Okcu MF, Despa S, Raney RB: Synovial sarcoma in children: surgical lessons from a single institution and review of the literature. J Am Coll Surg. 2001, 192 (3): 305-313. 10.1016/S1072-7515(00)00806-1.CrossRefPubMed Andrassy RJ, Okcu MF, Despa S, Raney RB: Synovial sarcoma in children: surgical lessons from a single institution and review of the literature. J Am Coll Surg. 2001, 192 (3): 305-313. 10.1016/S1072-7515(00)00806-1.CrossRefPubMed
9.
go back to reference Mullen JR, Zagars GK: Synovial sarcoma outcome following conservation surgery and radiotherapy. Radiother Oncol. 1994, 33 (1): 23-30. 10.1016/0167-8140(94)90082-5.CrossRefPubMed Mullen JR, Zagars GK: Synovial sarcoma outcome following conservation surgery and radiotherapy. Radiother Oncol. 1994, 33 (1): 23-30. 10.1016/0167-8140(94)90082-5.CrossRefPubMed
10.
go back to reference Carson JH, Harwood AR, Cummings BJ, Fornasier V, Langer F, Quirt I: The place of radiotherapy in the treatment of synovial sarcoma. Int J Radiat Oncol Biol Phys. 1981, 7 (1): 49-53. 10.1016/0360-3016(81)90059-6.CrossRefPubMed Carson JH, Harwood AR, Cummings BJ, Fornasier V, Langer F, Quirt I: The place of radiotherapy in the treatment of synovial sarcoma. Int J Radiat Oncol Biol Phys. 1981, 7 (1): 49-53. 10.1016/0360-3016(81)90059-6.CrossRefPubMed
11.
go back to reference Nielsen GP, Shaw PA, Rosenberg AE, Dickersin GR, Young RH, Scully RE: Synovial sarcoma of the vulva: a report of two cases. Mod Pathol. 1996, 9 (10): 970-974.PubMed Nielsen GP, Shaw PA, Rosenberg AE, Dickersin GR, Young RH, Scully RE: Synovial sarcoma of the vulva: a report of two cases. Mod Pathol. 1996, 9 (10): 970-974.PubMed
12.
go back to reference Ambani DS, White B, Kaplan AL, Alberto A: A case of monophasic synovial sarcoma presenting as a vulvar mass. Gynecol Oncol. 2006, 100 (2): 433-436. 10.1016/j.ygyno.2005.09.013.CrossRefPubMed Ambani DS, White B, Kaplan AL, Alberto A: A case of monophasic synovial sarcoma presenting as a vulvar mass. Gynecol Oncol. 2006, 100 (2): 433-436. 10.1016/j.ygyno.2005.09.013.CrossRefPubMed
13.
go back to reference White BE, Kaplan A, Lopez-Terrada DH, Ro JY, Benjamin RS, Ayala AG: Monophasic synovial sarcoma arising in the vulva: a case report and review of the literature. Arch Pathol Lab Med. 2008, 132 (4): 698-702.PubMed White BE, Kaplan A, Lopez-Terrada DH, Ro JY, Benjamin RS, Ayala AG: Monophasic synovial sarcoma arising in the vulva: a case report and review of the literature. Arch Pathol Lab Med. 2008, 132 (4): 698-702.PubMed
Metadata
Title
Synovial sarcoma of the vulva: a case report
Authors
Viren Asher
Gerhard van Schalkwyk
Anish Bali
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-5-95

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