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Journal of Medical Case Reports
Published in: Journal of Medical Case Reports 1/2011

Open Access 01-12-2011 | Case report

Gastrointestinal relapse of multiple myeloma and sustained response to lenalidomide: a case report

Authors: Patrick R Benusiglio, Thomas A McKee, Xavier Montet, Jean-Marc Dumonceau, Laurence Favet, Anne-Claude George, Pierre-Yves Dietrich

Published in: Journal of Medical Case Reports | Issue 1/2011

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Abstract

Introduction

Gastrointestinal relapse in patients with multiple myeloma is very rare and, when reported, always associated with a poor prognosis.

Case presentation

We describe the case of a 71-year-old Caucasian man who presented with life-threatening hematemesis and melena due to a digestive relapse of his multiple myeloma. Despite the active hemorrhage, we initiated a third-line treatment with lenalidomide. The response was spectacular and long-lasting.

Conclusions

Clinicians must consider digestive tract involvement in myeloma patients presenting with a gastrointestinal hemorrhage. Furthermore, myeloma patients do benefit from novel oral drugs, even when they are critically ill.
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Metadata
Title
Gastrointestinal relapse of multiple myeloma and sustained response to lenalidomide: a case report
Authors
Patrick R Benusiglio
Thomas A McKee
Xavier Montet
Jean-Marc Dumonceau
Laurence Favet
Anne-Claude George
Pierre-Yves Dietrich
Publication date
01-12-2011
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2011
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-5-110

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