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Published in: Journal of Medical Case Reports 1/2010

Open Access 01-12-2010 | Case report

Keratitis caused by the recently described new species Aspergillus brasiliensis: two case reports

Authors: Palanisamy Manikandan, János Varga, Sándor Kocsubé, Rajaraman Revathi, Raghavan Anita, Ilona Dóczi, Tibor Mihály Németh, Venkatapathy Narendran, Csaba Vágvölgyi, Madhavan Bhaskar, Chockaiya Manoharan, Robert A Samson, László Kredics

Published in: Journal of Medical Case Reports | Issue 1/2010

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Abstract

Introduction

Human infections caused by Aspergillus brasiliensis have not yet been reported. We describe the first two known cases of fungal keratitis caused by Aspergillus brasiliensis.

Case presentations

A 49-year-old Indian Tamil woman agricultural worker came with pain and defective vision in the right eye for one month. Meanwhile, a 35-year-old Indian Tamil woman presented with a history of a corneal ulcer involving the left eye for 15 days. The fungal strains isolated from these two cases were originally suspected to belong to Aspergillus section Nigri based on macro- and micromorphological characteristics. Molecular identification revealed that both isolates represent A. brasiliensis.

Conclusion

The two A. brasiliensis strains examined in this study were part of six keratitis isolates from Aspergillus section Nigri, suggesting that this recently described species may be responsible for a significant proportion of corneal infections caused by black Aspergilli. The presented cases also indicate that significant differences may occur between the severities of keratitis caused by individual isolates of A. brasiliensis.
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Metadata
Title
Keratitis caused by the recently described new species Aspergillus brasiliensis: two case reports
Authors
Palanisamy Manikandan
János Varga
Sándor Kocsubé
Rajaraman Revathi
Raghavan Anita
Ilona Dóczi
Tibor Mihály Németh
Venkatapathy Narendran
Csaba Vágvölgyi
Madhavan Bhaskar
Chockaiya Manoharan
Robert A Samson
László Kredics
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2010
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-4-68

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