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Published in: Journal of Medical Case Reports 1/2010

Open Access 01-12-2010 | Case report

Nonpreserved amniotic membrane transplantation for bilateral toxic keratopathy caused by topical anesthetic abuse: a case report

Authors: Ayse Asyali Altinok, Melike Balikoglu, Emine Sen, Kurtulus Serdar

Published in: Journal of Medical Case Reports | Issue 1/2010

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Abstract

Introduction

Corneal damage associated with abuse of topical anesthetics is a rare clinic entity. Topical anesthetic abuse is one of the causes of ring keratitis. Ring keratitis is easily overlooked because it can mimic acanthamoeba keratitis or other infectious keratitis. The outcome is often poor, leading to persistent epithelial defects, corneal scarring, and perforations.

Case presentation

We report the clinical presentation, diagnosis, and treatment of a 65-year-old Caucasian man, who worked as a health care worker, with bilateral toxic keratopathy caused by topical anesthetic abuse. Nonpreserved amniotic membrane transplantation was performed for both eyes of the patient.

Conclusion

It is important to identify and treat patients who abuse topical anesthetics before permanent vision loss ensues. Nonpreserved amniotic membrane transplantation may be useful in relieving pain and improving corneal surface in anesthetic agent abusers.
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Literature
1.
go back to reference Pharmakakis NM, Katsimpris JM, Melachrinou MP, Koliopoulos JX: Corneal complications following abuse of topical anesthetics. Eur J Ophthalmol. 2002, 12: 373-378.PubMed Pharmakakis NM, Katsimpris JM, Melachrinou MP, Koliopoulos JX: Corneal complications following abuse of topical anesthetics. Eur J Ophthalmol. 2002, 12: 373-378.PubMed
2.
go back to reference Varga JH, Rubinfeld RS, Wolf TC: Topical anesthetic abuse ring keratitis: report of four cases. Cornea. 1997, 16: 424-429.CrossRefPubMed Varga JH, Rubinfeld RS, Wolf TC: Topical anesthetic abuse ring keratitis: report of four cases. Cornea. 1997, 16: 424-429.CrossRefPubMed
3.
go back to reference Rosenwasser GO, Holland S, Pflugfelder SC: Topical anesthetic abuse. Ophthalmology. 1990, 97: 967-972.CrossRefPubMed Rosenwasser GO, Holland S, Pflugfelder SC: Topical anesthetic abuse. Ophthalmology. 1990, 97: 967-972.CrossRefPubMed
4.
go back to reference Smith RB, Everett WG: Physiology and pharmacology of local anesthetic agents. Int Ophthalmol Clin. 1973, 13: 35-60.PubMed Smith RB, Everett WG: Physiology and pharmacology of local anesthetic agents. Int Ophthalmol Clin. 1973, 13: 35-60.PubMed
5.
go back to reference Ucakhan OO, Koklu G, Firat E: Nonpreserved human amniotic membrane transplantation in acute and chronic chemical eye injuries. Cornea. 2002, 21: 169-172. 10.1097/00003226-200203000-00008.CrossRefPubMed Ucakhan OO, Koklu G, Firat E: Nonpreserved human amniotic membrane transplantation in acute and chronic chemical eye injuries. Cornea. 2002, 21: 169-172. 10.1097/00003226-200203000-00008.CrossRefPubMed
6.
go back to reference Srinivasan R, T SS, Gupta A, Kaliaperumal S: Hypopyon iritis after primary fresh amniotic membrane transplantation. Cornea. 2007, 26: 1275-1276. 10.1097/ICO.0b013e31814b8b94.CrossRefPubMed Srinivasan R, T SS, Gupta A, Kaliaperumal S: Hypopyon iritis after primary fresh amniotic membrane transplantation. Cornea. 2007, 26: 1275-1276. 10.1097/ICO.0b013e31814b8b94.CrossRefPubMed
7.
go back to reference American Academy of Ophthalmology: Clinical approach to uveitis. 2005, Intraocular inflammation and uveitis. San Francisco, Leo, 106- American Academy of Ophthalmology: Clinical approach to uveitis. 2005, Intraocular inflammation and uveitis. San Francisco, Leo, 106-
Metadata
Title
Nonpreserved amniotic membrane transplantation for bilateral toxic keratopathy caused by topical anesthetic abuse: a case report
Authors
Ayse Asyali Altinok
Melike Balikoglu
Emine Sen
Kurtulus Serdar
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2010
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-4-262

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