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Journal of Medical Case Reports

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Open Access 01-12-2010 | Case report

Successful treatment of recurrent small bowel adenocarcinoma by cytoreductive surgery and chemotherapy: a case report and review of the literature

Authors: Tomoki Yamano, Eiichi Morii, Isao Arai, Toshiaki Takada, Katsuyuki Aozasa

Published in: Journal of Medical Case Reports | Issue 1/2010

Abstract

Introduction

Small bowel adenocarcinoma is a rare malignancy associated with a poor prognosis and there is little evidence of effective treatment. Recurrent small bowel adenocarcinoma is an intractable disease for which there is little information available regarding its treatment by palliative therapy. We present a case of recurrent small bowel adenocarcinoma successfully treated by cytoreductive surgery and palliative chemotherapy.

Case presentation

We report the case of a 72-year-old Japanese female who developed a peritoneal metastasis from recurrent small bowel adenocarcinoma after curative resection and adjuvant chemotherapy with S-1 and polysaccharide K. She underwent cytoreductive surgery followed by chemotherapy with folinic acid/fluorouracil/oxaliplatin and folinic acid/fluorouracil/irinotecan with polysaccharide K. Subsequently, no sign of a recurrence was observed 42 months after the second operation.

Conclusion

To the best of our knowledge, this is the first case report of the successful treatment of peritoneal metastasis from small bowel adenocarcinoma by cytoreductive surgery and combination chemotherapy (folinic acid/fluorouracil/oxaliplatin and folinic acid/fluorouracil/irinotecan with polysaccharide K).

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Title: Successful treatment of recurrent small bowel adenocarcinoma by cytoreductive surgery and chemotherapy: a case report and review of the literature
Authors: Tomoki Yamano
Eiichi Morii
Isao Arai
Toshiaki Takada
Katsuyuki Aozasa
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Journal of Medical Case Reports / Issue 1/2010
Electronic ISSN: 1752-1947
DOI: https://doi.org/10.1186/1752-1947-4-213

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Successful treatment of recurrent small bowel adenocarcinoma by cytoreductive surgery and chemotherapy: a case report and review of the literature

Abstract

Introduction

Case presentation

Conclusion

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Introduction

Case presentation

Conclusion

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