Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2009

Open Access 01-12-2009 | Case report

Intracystic papillary carcinoma in a male as a rare presentation of breast cancer: a case report and literature review

Authors: Laszlo Romics Jr, M Emmet O'Brien, Norma Relihan, Fionnuala O'Connell, H Paul Redmond

Published in: Journal of Medical Case Reports | Issue 1/2009

Login to get access

Abstract

Introduction

The term "intracystic papillary ductal carcinoma in situ" has recently changed and is now more appropriately referred to "intracystic papillary carcinoma". Intracystic papillary carcinoma in men is an extremely rare disease with only a few case presentations published in the literature so far.

Case presentation

We discuss a case of a 44-year-old Caucasian man with an intracystic papillary carcinoma treated with simple mastectomy, sentinel lymph-node biopsy and contralateral risk-reducing mastectomy. These were followed by adjuvant radiotherapy of the breast.

Conclusion

Triple assessment (i.e. clinical examination and radiological and histological assessment) with a high level of clinical suspicion is necessary to diagnose intracystic papillary carcinoma in men due to its rarity. Furthermore, genetic testing and risk-reducing mastectomy should also be considered in cases of a strong family history for male breast cancer.
Appendix
Available only for authorised users
Literature
1.
go back to reference Anderson WF, Devesa SS: In situ male breast carcinoma in the Surveillance, Epidemiology, and End Results database of the National Cancer Institute. Cancer. 2005, 104: 1733-1741. 10.1002/cncr.21353.CrossRefPubMed Anderson WF, Devesa SS: In situ male breast carcinoma in the Surveillance, Epidemiology, and End Results database of the National Cancer Institute. Cancer. 2005, 104: 1733-1741. 10.1002/cncr.21353.CrossRefPubMed
2.
go back to reference Solorzano CC, Middleton LP, Hunt KK, Mirza N, Meric F, Kuerer HM, Ross MI, Ames FC, Feig BW, Pollock RE, Singletary SE, Babiera G: Treatment and outcome of patients with intracystic papillary carcinoma of the breast. Am J Surg. 2002, 184: 364-368. 10.1016/S0002-9610(02)00941-8.CrossRefPubMed Solorzano CC, Middleton LP, Hunt KK, Mirza N, Meric F, Kuerer HM, Ross MI, Ames FC, Feig BW, Pollock RE, Singletary SE, Babiera G: Treatment and outcome of patients with intracystic papillary carcinoma of the breast. Am J Surg. 2002, 184: 364-368. 10.1016/S0002-9610(02)00941-8.CrossRefPubMed
3.
4.
go back to reference Dragoumis DM, Tsiftsoglou AP: Intracystic papillary carcinoma associated with ductal carcinoma in situ in a male breast. J Postgrad Med. 2008, 54: 39-40.CrossRefPubMed Dragoumis DM, Tsiftsoglou AP: Intracystic papillary carcinoma associated with ductal carcinoma in situ in a male breast. J Postgrad Med. 2008, 54: 39-40.CrossRefPubMed
5.
go back to reference Collins LC, Carlo VP, Hwang H, Barry TS, Gown AM, Schnitt SJ: Intracystic papillary carcinomas of the breast: a reevaluation using a panel of myoepithelial cell markers. Am J Surg Pathol. 2006, 30: 1002-1007. 10.1097/00000478-200608000-00011.CrossRefPubMed Collins LC, Carlo VP, Hwang H, Barry TS, Gown AM, Schnitt SJ: Intracystic papillary carcinomas of the breast: a reevaluation using a panel of myoepithelial cell markers. Am J Surg Pathol. 2006, 30: 1002-1007. 10.1097/00000478-200608000-00011.CrossRefPubMed
6.
go back to reference Sinha S, Hughes RG, Ryley NG: Papillary carcinoma in a male breast cyst: a diagnostic challenge. Ann R Coll Surg Engl. 2006, 88: W3-5. 10.1308/147870806X129232.CrossRefPubMedPubMedCentral Sinha S, Hughes RG, Ryley NG: Papillary carcinoma in a male breast cyst: a diagnostic challenge. Ann R Coll Surg Engl. 2006, 88: W3-5. 10.1308/147870806X129232.CrossRefPubMedPubMedCentral
7.
go back to reference Kinoshita T, Fukutomi T, Iwamoto E, Takasugi M, Akashi-Tanaka S, Hasegawa T: Intracystic papillary carcinoma of the breast in a male patient diagnosed by core needle biopsy: a case report. Breast. 2005, 14: 322-324. 10.1016/j.breast.2004.12.003.CrossRefPubMed Kinoshita T, Fukutomi T, Iwamoto E, Takasugi M, Akashi-Tanaka S, Hasegawa T: Intracystic papillary carcinoma of the breast in a male patient diagnosed by core needle biopsy: a case report. Breast. 2005, 14: 322-324. 10.1016/j.breast.2004.12.003.CrossRefPubMed
8.
go back to reference Andrés B, Aguilar J, Torroba A, Martínez-Gálvez M, Aguayo JL: Intracystic papillary carcinoma in the male breast. Breast J. 2003, 9: 249-250. 10.1046/j.1524-4741.2003.09314.x.CrossRefPubMed Andrés B, Aguilar J, Torroba A, Martínez-Gálvez M, Aguayo JL: Intracystic papillary carcinoma in the male breast. Breast J. 2003, 9: 249-250. 10.1046/j.1524-4741.2003.09314.x.CrossRefPubMed
9.
go back to reference Blaumeiser B, Tjalma WA, Verslegers I, De Schepper AM, Buytaert P: Invasive papillary carcinoma of the male breast. Eur Radiol. 2002, 12: 2207-2210.CrossRefPubMed Blaumeiser B, Tjalma WA, Verslegers I, De Schepper AM, Buytaert P: Invasive papillary carcinoma of the male breast. Eur Radiol. 2002, 12: 2207-2210.CrossRefPubMed
10.
go back to reference Lefkowitz M, Lefkowitz W, Wargotz ES: Intraductal (intracystic) papillary carcinoma of the breast and its variants: a clinicopathological study of 77 cases. Hum Pathol. 1994, 25: 802-809. 10.1016/0046-8177(94)90250-X.CrossRefPubMed Lefkowitz M, Lefkowitz W, Wargotz ES: Intraductal (intracystic) papillary carcinoma of the breast and its variants: a clinicopathological study of 77 cases. Hum Pathol. 1994, 25: 802-809. 10.1016/0046-8177(94)90250-X.CrossRefPubMed
11.
go back to reference Hill CB, Yeh IT: Myoepithelial cell staining patterns of papillary breast lesions: from intraductal papillomas to invasive papillary carcinomas. Am J Clin Pathol. 2005, 123: 36-44. 10.1309/XG7TPQ16DMJAV8P1.CrossRefPubMed Hill CB, Yeh IT: Myoepithelial cell staining patterns of papillary breast lesions: from intraductal papillomas to invasive papillary carcinomas. Am J Clin Pathol. 2005, 123: 36-44. 10.1309/XG7TPQ16DMJAV8P1.CrossRefPubMed
12.
go back to reference Ganesan S, Karthik G, Joshi M, Damodaran V: Ultrasound spectrum in intraductal papillary neoplasms of breast. Br J Radiol. 2006, 79: 843-849. 10.1259/bjr/69395941.CrossRefPubMed Ganesan S, Karthik G, Joshi M, Damodaran V: Ultrasound spectrum in intraductal papillary neoplasms of breast. Br J Radiol. 2006, 79: 843-849. 10.1259/bjr/69395941.CrossRefPubMed
13.
go back to reference Levine PH, Waisman J, Yang GC: Aspiration cytology of cystic carcinoma of the breast. Diagn Cytopathol. 2003, 28: 39-44. 10.1002/dc.10209.CrossRefPubMed Levine PH, Waisman J, Yang GC: Aspiration cytology of cystic carcinoma of the breast. Diagn Cytopathol. 2003, 28: 39-44. 10.1002/dc.10209.CrossRefPubMed
14.
go back to reference Fayanju OM, Ritter J, Gillanders WE, Eberlein TJ, Dietz JR, Aft R, Margenthaler JA: Therapeutic management of intracystic papillary carcinoma of the breast: the roles of radiation and endocrine therapy. Am J Surg. 2007, 194: 497-500. 10.1016/j.amjsurg.2007.06.016.CrossRefPubMed Fayanju OM, Ritter J, Gillanders WE, Eberlein TJ, Dietz JR, Aft R, Margenthaler JA: Therapeutic management of intracystic papillary carcinoma of the breast: the roles of radiation and endocrine therapy. Am J Surg. 2007, 194: 497-500. 10.1016/j.amjsurg.2007.06.016.CrossRefPubMed
15.
go back to reference Fentiman IS, Fourquet A, Hortobagyi GN: Male breast cancer. Review. Lancet. 2006, 367: 595-604. 10.1016/S0140-6736(06)68226-3.CrossRefPubMed Fentiman IS, Fourquet A, Hortobagyi GN: Male breast cancer. Review. Lancet. 2006, 367: 595-604. 10.1016/S0140-6736(06)68226-3.CrossRefPubMed
Metadata
Title
Intracystic papillary carcinoma in a male as a rare presentation of breast cancer: a case report and literature review
Authors
Laszlo Romics Jr
M Emmet O'Brien
Norma Relihan
Fionnuala O'Connell
H Paul Redmond
Publication date
01-12-2009
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2009
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-3-13

Other articles of this Issue 1/2009

Journal of Medical Case Reports 1/2009 Go to the issue