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Journal of Medical Case Reports

Open Access 01-12-2008 | Case report

Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report

Authors: Felix Gundling, Henning Wittenburg, Andrea Tannapfel, Joachim Mossner

Published in: Journal of Medical Case Reports | Issue 1/2008

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Abstract

Introduction

Whipple's disease is a rare systemic infectious disorder caused by Tropheryma whipplei.

Case presentation

We report a 68-year-old male with Whipple's disease of the central nervous system following long-term antibiotic therapy and many years after the initial clinical onset.

Conclusion

The combination of trimethoprim and sulphamethoxazole does not prevent or cure involvement of the central nervous system in all patients with Whipple's disease. If relapse of the central nervous system occurs treatment with meropenem might be a useful alternative.
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Metadata
Title
Neurological presentation of Whipple's disease after long-term antibiotic treatment: a case report
Authors
Felix Gundling
Henning Wittenburg
Andrea Tannapfel
Joachim Mossner
Publication date
01-12-2008
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2008
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-2-191