Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Journal of Medical Case Reports
Published in: Journal of Medical Case Reports 1/2007

Open Access 01-12-2007 | Case report

External beam irradiation of myocardial carcinoid metastases: a case report

Authors: Jonathan Strosberg, Sarah Hoffe, Todd Hazelton, Larry Kvols

Published in: Journal of Medical Case Reports | Issue 1/2007

Login to get access

Abstract

The heart is an exceedingly rare site of metastatic involvement in carcinoid tumors. Only nineteen cases have been described in the literature over the past 30 years. We report here on a patient who presented with progressive carcinoid syndrome despite surgical resection of her liver metastases. She was found to have cardiac metastases on inidium-111-pentetreotide scintigraphy and subsequently underwent external beam radiation to the heart resulting in symptomatic palliation of her syndrome and objective radiographic response. To our knowledge, this is the first reported case of metastatic cardiac carcinoid treated with external beam irradiation.
Appendix
Available only for authorised users
Literature
1.
Pandya UH, Pellikka PA, Enriquez-Sarano M, Edwards WD, Schaff HV, Connolly HM: Metastatic carcinoid tumor to the heart: echocardiographic-pathologic study of 11 patients. J Am Coll Cardiol. 2002, 40 (7): 1328-1332. 10.1016/S0735-1097(02)02109-5.CrossRefPubMed
2.
Pellikka PA, Tajik AJ, Khandheria BK, Seward JB, Callahan JA, Pitot HC, Kvols LK: Carcinoid heart disease. Clinical and echocardiographic spectrum in 74 patients. Circulation. 1993, 87 (4): 1188-1196.CrossRefPubMed
3.
Puvaneswary M, Thomson D, Bellamy GR: Cardiac metastasis from carcinoid tumour: magnetic resonance imaging findings. Australas Radiol. 2004, 48 (3): 383-387. 10.1111/j.0004-8461.2004.01323.x.CrossRefPubMed
4.
Yeung HW, Imbriaco M, Zhang JJ, Macapinlac H, Goldsmith SJ, Larson SM: Visualization of myocardial metastasis of carcinoid tumor by indium-111-pentetreotide. J Nucl Med. 1996, 37 (9): 1528-1530.PubMed
5.
Drake WM, Jenkins PJ, Phillips RR, Lowe DG, Grossman AB, Besser GM, Wass JA: Intracardiac metastases from neuroendocrine tumours. Clin Endocrinol (Oxf). 1997, 46 (4): 517-522. 10.1046/j.1365-2265.1997.1440958.x.CrossRef
6.
Rich LL, Lisa CP, Nasser WK: Carcinoid pericarditis. Am J Med. 1973, 54 (4): 522-527. 10.1016/0002-9343(73)90048-X.CrossRefPubMed
7.
Shehata BM, Thomas JE, Doudenko-Rufforny I: Metastatic carcinoid to the conducting system-is it a rare or merely unrecognized manifestation of carcinoid cardiopathy?. Arch Pathol Lab Med. 2002, 126 (12): 1538-1540.PubMed
8.
Schupak KD, Wallner KE: The role of radiation therapy in the treatment of locally unresectable or metastatic carcinoid tumors. Int J Radiat Oncol Biol Phys. 1991, 20 (3): 489-495.CrossRefPubMed
9.
Chakravarthy A, Abrams RA: Radiation therapy in the management of patients with malignant carcinoid tumors. Cancer. 1995, 75 (6): 1386-1390. 10.1002/1097-0142(19950315)75:6<1386::AID-CNCR2820750622>3.0.CO;2-U.CrossRefPubMed
10.
Stewart JR, Fajardo LF: Dose response in human and experimental radiation-induced heart disease. Application of the nominal standard dose (NSD) concept. Radiology. 1971, 99 (2): 403-408.CrossRefPubMed
11.
Carmel RJ, Kaplan HS: Mantle irradiation in Hodgkin's disease. An analysis of technique, tumor eradication, and complications. Cancer. 1976, 37 (6): 2813-2825. 10.1002/1097-0142(197606)37:6<2813::AID-CNCR2820370637>3.0.CO;2-S.CrossRefPubMed
12.
Hancock SL, Tucker MA, Hoppe RT: Factors affecting late mortality from heart disease after treatment of Hodgkin's disease. Jama. 1993, 270 (16): 1949-1955. 10.1001/jama.270.16.1949.CrossRefPubMed
13.
Adams MJ, Lipshultz SE, Schwartz C, Fajardo LF, Coen V, Constine LS: Radiation-associated cardiovascular disease: manifestations and management. Semin Radiat Oncol. 2003, 13 (3): 346-356. 10.1016/S1053-4296(03)00026-2.CrossRefPubMed
Metadata
Title
External beam irradiation of myocardial carcinoid metastases: a case report
Authors
Jonathan Strosberg
Sarah Hoffe
Todd Hazelton
Larry Kvols
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2007
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-1-95

Other articles of this Issue 1/2007

Journal of Medical Case Reports 1/2007 Go to the issue

Case report

Atrial and placental melanoma metastasis: a case report and literature review

Case report

Traumatic pulmonary pseuodocysts: two case reports

Case report

Bouveret's syndrome as an unusual cause of gastric outlet obstruction: a case report

Case report

Cystic fibrosis and renal disease: a case report

Case report

Bullet-induced synovitis as a cause of secondary osteoarthritis of the hip joint: A case report and review of literature

Case report

A case of penile fracture with complete urethral disruption during sexual intercourse: a case report