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Published in: Journal of Medical Case Reports 1/2007

Open Access 01-12-2007 | Case report

Amniotic membrane transplantation for wound dehiscence after deep lamellar keratoplasty: a case report

Authors: Tetsuya Kawakita, Tamaki Sumi, Murat Dogru, Kazuo Tsubota, Jun Shimazaki

Published in: Journal of Medical Case Reports | Issue 1/2007

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Abstract

Purpose

To report amniotic membrane (AM) transplantation in a patient with wound dehiscence 5 months after deep lamellar keratoplasty (DLKP)

Methods

The patient was an 84-year-old Japanese man who had undergone right DLKP 5 months earlier for central corneal scarring due to recurrent stromal herpetic keratitis. He developed wound dehiscence with corneal stromal melting due to recurrence of stromal herpes in both the donor and recipient sites. "AM roll-in filling technique" and AM patching were performed.

Results

Following AM transplantation, stromal inflammation subsided and complete epithelization occurred within 10 days of surgery.
At 8 months postoperatively, biomicroscopy revealed stable wound apposition or stromal gain. Following AM transplantation, stromal inflammation subsided and complete epithelialization was achieved within 10 days after surgery.

Conclusion

AM transplantation may offer an effective treatment modality for herpetic corneal wound dehiscence after DLKP.
Appendix
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Literature
1.
go back to reference Kim JC, Tseng SC: Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas. Cornea. 1995, 14: 473-84. 10.1097/00003226-199509000-00006.CrossRefPubMed Kim JC, Tseng SC: Transplantation of preserved human amniotic membrane for surface reconstruction in severely damaged rabbit corneas. Cornea. 1995, 14: 473-84. 10.1097/00003226-199509000-00006.CrossRefPubMed
2.
go back to reference Hanada K, Shimazaki J, Shimmura S, Tsubota K: Multilayered amniotic membrane trans p9–85. lantation for severe ulceration of the cornea and sclera. 2001, 131: 324-331. Hanada K, Shimazaki J, Shimmura S, Tsubota K: Multilayered amniotic membrane trans p9–85. lantation for severe ulceration of the cornea and sclera. 2001, 131: 324-331.
3.
go back to reference Shimmura S, Shimazaki J, Ohashi Y, Tsubota K: Antiinflammatory effects of amniotic membrane transplantation in ocular surface disorders. Cornea. 2001, 20: 408-13. 10.1097/00003226-200105000-00015.CrossRefPubMed Shimmura S, Shimazaki J, Ohashi Y, Tsubota K: Antiinflammatory effects of amniotic membrane transplantation in ocular surface disorders. Cornea. 2001, 20: 408-13. 10.1097/00003226-200105000-00015.CrossRefPubMed
4.
go back to reference Heiligenhaus A, Li H, Hernandez Galindo EE, Koch JM, Steuhl KP, Meller D: Management of acute ulcerative and necrotising herpes simplex and zoster keratitis with amniotic membrane transplantation. Br J Ophthalmol. 2003, 87: 1215-19. 10.1136/bjo.87.10.1215.CrossRefPubMedPubMedCentral Heiligenhaus A, Li H, Hernandez Galindo EE, Koch JM, Steuhl KP, Meller D: Management of acute ulcerative and necrotising herpes simplex and zoster keratitis with amniotic membrane transplantation. Br J Ophthalmol. 2003, 87: 1215-19. 10.1136/bjo.87.10.1215.CrossRefPubMedPubMedCentral
5.
go back to reference Heiligenhaus A, Li HF, Yang Y, WAsmuth S, Steuhl KP, Bauer D: Transplantation of amniotic membrane in murine herpes stromal keratitis modulates matrix metalloproteinases in the cornea. Invest Ophthalmol Vis Sci. 2005, 46: 407-10.1167/iovs.05-0192.CrossRef Heiligenhaus A, Li HF, Yang Y, WAsmuth S, Steuhl KP, Bauer D: Transplantation of amniotic membrane in murine herpes stromal keratitis modulates matrix metalloproteinases in the cornea. Invest Ophthalmol Vis Sci. 2005, 46: 407-10.1167/iovs.05-0192.CrossRef
Metadata
Title
Amniotic membrane transplantation for wound dehiscence after deep lamellar keratoplasty: a case report
Authors
Tetsuya Kawakita
Tamaki Sumi
Murat Dogru
Kazuo Tsubota
Jun Shimazaki
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2007
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-1-28

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