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Published in: Journal of Medical Case Reports 1/2007

Open Access 01-12-2007 | Case report

Topical latanoprost causes posterior movement of lens in a patient with exfoliation syndrome and subluxated lens: a case report

Authors: Takashi Kanamoto, Michiya Takamatsu, Yoshiaki Kiuchi

Published in: Journal of Medical Case Reports | Issue 1/2007

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Abstract

Introduction

To report the effect of topical latanoprost on the position of a subluxated lens.

Case presentation

After 0.005% latanoprost was administered topically to a patient with ocular hypertension due to a pseudoexfoliation syndrome and a subluxated lens, the position of the lens was examined by slit-lamp biomicroscopy, and the ciliary body thickness by ultrasound biomicroscopy. The lens had moved posteriorly, and the thickness of the ciliary body had decreased after the latanoprost.

Conclusion

We suggest that the decrease in the thickness of the ciliary body resulted in an increase in the tension of the zonule of Zinn fibers, thus pulling the subluxated lens posteriorly.
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Literature
1.
go back to reference Mishima HK, Shoge K, Takamatsu M, Kiuchi Y, Tanaka J: Ultrasound Biomicroscopic study of ciliary body thickness after topical application of pharmacogic agents. Am J Ophthalmol. 1996, 121: 319-321.CrossRefPubMed Mishima HK, Shoge K, Takamatsu M, Kiuchi Y, Tanaka J: Ultrasound Biomicroscopic study of ciliary body thickness after topical application of pharmacogic agents. Am J Ophthalmol. 1996, 121: 319-321.CrossRefPubMed
2.
go back to reference Mishima HK, Masuda K, Kitazawa Y, Azuma I: A comparison of latanoprost and timolol in primary open-angle glaucoma and ocular hypertension. A 12-week study. Arch Ophthalmol. 1996, 114: 929-932.CrossRefPubMed Mishima HK, Masuda K, Kitazawa Y, Azuma I: A comparison of latanoprost and timolol in primary open-angle glaucoma and ocular hypertension. A 12-week study. Arch Ophthalmol. 1996, 114: 929-932.CrossRefPubMed
3.
go back to reference Toris CB, Camras CB, Yablonski ME: Effect of PhXA41, a new prostaglandin F2α analog, on aqueous humor dynamics in human eyes. Ophthalmology. 1993, 100: 1297-1304.CrossRefPubMed Toris CB, Camras CB, Yablonski ME: Effect of PhXA41, a new prostaglandin F2α analog, on aqueous humor dynamics in human eyes. Ophthalmology. 1993, 100: 1297-1304.CrossRefPubMed
4.
go back to reference Yousufuzai SY, Zheng P, Abdel-Latif AA: Protaglandin F2α and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species. Exp Eye Res. 1996, 63: 305-310. 10.1006/exer.1996.0119.CrossRef Yousufuzai SY, Zheng P, Abdel-Latif AA: Protaglandin F2α and its analogs induce release of endogenous prostaglandins in iris and ciliary muscles isolated from cat and other mammalian species. Exp Eye Res. 1996, 63: 305-310. 10.1006/exer.1996.0119.CrossRef
5.
go back to reference Lindsey JD, Kashiwagi K, Kashiwagi F, Weinreb RN: Prostaglandins alter extracellular matrix adjacent to human ciliary muscle cells in vitro. Invest Ophthalomol Vis Sci. 1997, 38: 2214-2223. Lindsey JD, Kashiwagi K, Kashiwagi F, Weinreb RN: Prostaglandins alter extracellular matrix adjacent to human ciliary muscle cells in vitro. Invest Ophthalomol Vis Sci. 1997, 38: 2214-2223.
6.
go back to reference Ocklind A: Effect of latanoprost on the extracellular matrix of ciliary muscle. A study on cultured cells and tissue sections. Exp Eye Res. 1998, 67: 179-191. 10.1006/exer.1998.0508.CrossRefPubMed Ocklind A: Effect of latanoprost on the extracellular matrix of ciliary muscle. A study on cultured cells and tissue sections. Exp Eye Res. 1998, 67: 179-191. 10.1006/exer.1998.0508.CrossRefPubMed
7.
go back to reference Konstas AG, Kozobolis VP, Tersis I, Leech J, Stewart WC: The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma. Eye. 2003, 17: 41-46. 10.1038/sj.eye.6700257.CrossRefPubMed Konstas AG, Kozobolis VP, Tersis I, Leech J, Stewart WC: The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma. Eye. 2003, 17: 41-46. 10.1038/sj.eye.6700257.CrossRefPubMed
8.
go back to reference Alm A, Schoenfelder J, McDermott J: A 5-year, multicenter, open-label, safety study of adjunctive latanoprost therapy for glaucoma. Arch Ophthalmol. 2004, 122: 957-965. 10.1001/archopht.122.7.957.CrossRefPubMed Alm A, Schoenfelder J, McDermott J: A 5-year, multicenter, open-label, safety study of adjunctive latanoprost therapy for glaucoma. Arch Ophthalmol. 2004, 122: 957-965. 10.1001/archopht.122.7.957.CrossRefPubMed
9.
go back to reference Goh Y, Hotehama Y, Mishima HK: Characterization of ciliary muscle relaxation induced by various agents in cats. Invest Ophthalmol Vis Sci. 1995, 36: 1188-1192.PubMed Goh Y, Hotehama Y, Mishima HK: Characterization of ciliary muscle relaxation induced by various agents in cats. Invest Ophthalmol Vis Sci. 1995, 36: 1188-1192.PubMed
10.
go back to reference Poyer JF, Millar C, Kaufman PL: Protaglandin F2α effects on isolated rhesus monkey ciliary muscle. Invest Ophthalmol Vis Sci . 1995, 36 (12): 2461-5.PubMed Poyer JF, Millar C, Kaufman PL: Protaglandin F2α effects on isolated rhesus monkey ciliary muscle. Invest Ophthalmol Vis Sci . 1995, 36 (12): 2461-5.PubMed
11.
go back to reference Fujimoto N, Zhao C, Shichi H: The effects of Protaglandin E2 and F2α on porcine ciliary muscle cells in culture. Curr Eye Res . 1995, 14 (12): 1155-63. 10.3109/02713689508995822.CrossRefPubMed Fujimoto N, Zhao C, Shichi H: The effects of Protaglandin E2 and F2α on porcine ciliary muscle cells in culture. Curr Eye Res . 1995, 14 (12): 1155-63. 10.3109/02713689508995822.CrossRefPubMed
12.
go back to reference Marchini G, Ghilotti G, Bonadimani M, Babighian S: Effects of 0.005% Latanoprost on Ocular Anterior Structures and Ciliary Body Thickness. J Glaucoma. 2003, 12: 295-300. 10.1097/00061198-200308000-00002.CrossRefPubMed Marchini G, Ghilotti G, Bonadimani M, Babighian S: Effects of 0.005% Latanoprost on Ocular Anterior Structures and Ciliary Body Thickness. J Glaucoma. 2003, 12: 295-300. 10.1097/00061198-200308000-00002.CrossRefPubMed
Metadata
Title
Topical latanoprost causes posterior movement of lens in a patient with exfoliation syndrome and subluxated lens: a case report
Authors
Takashi Kanamoto
Michiya Takamatsu
Yoshiaki Kiuchi
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2007
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-1-172

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