Skip to main content
Top
Published in: Journal of Medical Case Reports 1/2007

Open Access 01-12-2007 | Case report

Low-grade pelvic masses with spindle cell and fibroblastic proliferation: a case report

Authors: John Micha, Mark Rettenmaier, Douglas Ellison, John Brown, Bram Goldstein

Published in: Journal of Medical Case Reports | Issue 1/2007

Login to get access

Abstract

Background

Abdominal-pelvic masses containing spindle cell and fibroblastic proliferation are very rare. Since scant studies have reported on the pathologic characteristics inherent in this disease, appropriate clinical management is undetermined.

Case presentation

We report on an 87 year-old woman who presented with large abdominal pelvic masses, ascites, ureteral obstruction, and an elevated CA-125 serum level. The patient underwent surgical resection of the lesions and has since done very well. Final pathology revealed a low-grade ovarian tumor with spindle cell and fibroblastic proliferation.

Conclusion

To the best of our knowledge, this appears to be the only reported clinical case of a patient with this rare histology.
Appendix
Available only for authorised users
Literature
1.
go back to reference Mentzel T, Calonje E, Wadden C, Camplejohn RS, Beham A, Smith MA, Fletcher CD: Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant. Am J Surg Pathol. 1996, 20: 391-405. 10.1097/00000478-199604000-00001.CrossRefPubMed Mentzel T, Calonje E, Wadden C, Camplejohn RS, Beham A, Smith MA, Fletcher CD: Myxofibrosarcoma. Clinicopathologic analysis of 75 cases with emphasis on the low-grade variant. Am J Surg Pathol. 1996, 20: 391-405. 10.1097/00000478-199604000-00001.CrossRefPubMed
2.
go back to reference Brandwein-Gensler MS, Wang BY, Urken ML: Spindle Cell Transformation of Papillary Carcinoma: An Aggressive Entity Distinct From Anaplastic Thyroid Carcinoma. Arch Pathol Lab Med. 2004, 128: 87-89.PubMed Brandwein-Gensler MS, Wang BY, Urken ML: Spindle Cell Transformation of Papillary Carcinoma: An Aggressive Entity Distinct From Anaplastic Thyroid Carcinoma. Arch Pathol Lab Med. 2004, 128: 87-89.PubMed
3.
go back to reference Antonescu CR, Baren A: Spectrum of low-grade fibrosarcomas: a comparative ultrastructural analysis of low-grade myxofibrosarcoma and fibromyxoid sarcoma. Ultrastruct Pathol. 2004, 28: 321-32. 10.1080/019131290882259.CrossRefPubMed Antonescu CR, Baren A: Spectrum of low-grade fibrosarcomas: a comparative ultrastructural analysis of low-grade myxofibrosarcoma and fibromyxoid sarcoma. Ultrastruct Pathol. 2004, 28: 321-32. 10.1080/019131290882259.CrossRefPubMed
4.
go back to reference Ro JY, el-Naggar AK, Amin MB, Sahin AA, Ordonez NG, Ayala AG: Pseudosarcomatous fibromyxoid tumor of the urinary bladder and prostate: immunohistochemical, ultrastructural, and DNA flow cytometric analyses of nine cases. Hum Pathol. 1993, 24: 1203-10. 10.1016/0046-8177(93)90217-5.CrossRefPubMed Ro JY, el-Naggar AK, Amin MB, Sahin AA, Ordonez NG, Ayala AG: Pseudosarcomatous fibromyxoid tumor of the urinary bladder and prostate: immunohistochemical, ultrastructural, and DNA flow cytometric analyses of nine cases. Hum Pathol. 1993, 24: 1203-10. 10.1016/0046-8177(93)90217-5.CrossRefPubMed
5.
go back to reference Ding J, Hashimoto H, Imayama S, Tsuneyoshi M, Enjoji M: Spindle cell haemangioendothelioma: probably a benign vascular lesion not a low-grade angiosarcoma. A clinicopathological, ultrastructural and immunohistochemical study. Virchows Arch A Pathol Anat Histopathol. 1992, 420: 77-85. 10.1007/BF01605988.CrossRefPubMed Ding J, Hashimoto H, Imayama S, Tsuneyoshi M, Enjoji M: Spindle cell haemangioendothelioma: probably a benign vascular lesion not a low-grade angiosarcoma. A clinicopathological, ultrastructural and immunohistochemical study. Virchows Arch A Pathol Anat Histopathol. 1992, 420: 77-85. 10.1007/BF01605988.CrossRefPubMed
6.
go back to reference Koh SH, Choe HS, Lee IJ, Park HR, Bae SH: Low-grade fibromyxoid sarcoma: ultrasound and magnetic resonance findings in two cases. Skeletal Radiol. 2005, 34: 550-4. 10.1007/s00256-004-0876-5.CrossRefPubMed Koh SH, Choe HS, Lee IJ, Park HR, Bae SH: Low-grade fibromyxoid sarcoma: ultrasound and magnetic resonance findings in two cases. Skeletal Radiol. 2005, 34: 550-4. 10.1007/s00256-004-0876-5.CrossRefPubMed
7.
go back to reference Hansen T, Katenkamp K, Brodhun M, Katenkamp D: Low-grade fibrosarcoma- report on 39 not otherwise specified cases and comparison with defined low- grade fibrosarcoma types. Histopathology. 2006, 49: 152-60. 10.1111/j.1365-2559.2006.02480.x.CrossRefPubMed Hansen T, Katenkamp K, Brodhun M, Katenkamp D: Low-grade fibrosarcoma- report on 39 not otherwise specified cases and comparison with defined low- grade fibrosarcoma types. Histopathology. 2006, 49: 152-60. 10.1111/j.1365-2559.2006.02480.x.CrossRefPubMed
Metadata
Title
Low-grade pelvic masses with spindle cell and fibroblastic proliferation: a case report
Authors
John Micha
Mark Rettenmaier
Douglas Ellison
John Brown
Bram Goldstein
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2007
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-1-16

Other articles of this Issue 1/2007

Journal of Medical Case Reports 1/2007 Go to the issue