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Published in: Journal of Medical Case Reports 1/2007

Open Access 01-12-2007 | Case report

Pulmonary cystic disease in HIV positive individuals in the Democratic Republic of Congo: three case reports

Authors: Steven F. J. Callens, Faustin Kitetele, Patricia Lelo, Nicole Shabani, Jean Lusiama, Okitolanda Wemakoy, Robert Colebunders, Frieda Behets, Annelies Van Rie

Published in: Journal of Medical Case Reports | Issue 1/2007

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Abstract

Pulmonary emphysema and bronchiectasis in HIV seropositive patients has been described in the presence of injection drug use, malnutrition, repeated opportunistic infections, such as Pneumocytis jirovici pneumonia and Mycobacterium tuberculosis infection, and has been linked to the presence of HIV virus in lung tissue. Given the high burden of pulmonary infections and malnutrition among people living with HIV in resource poor settings, these individuals may be at increased risk of developing pulmonary emphysema, potentially reducing the long term benefit of antiretroviral therapy (ART) if initiated late in the course of HIV infection.
In this report, we describe three HIV-infected individuals (one woman and two children) presenting with extensive pulmonary cystic disease.
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Literature
1.
go back to reference Diaz PT, King MA, Pacht ER, Wewers MD, Gadek JE, Nagaraja HN, Drake J, Clanton TL: Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers. Ann Intern Med. 2000, 132 (5): 369-372.CrossRefPubMed Diaz PT, King MA, Pacht ER, Wewers MD, Gadek JE, Nagaraja HN, Drake J, Clanton TL: Increased susceptibility to pulmonary emphysema among HIV-seropositive smokers. Ann Intern Med. 2000, 132 (5): 369-372.CrossRefPubMed
2.
go back to reference Sheikh S, Madiraju K, Steiner P, Rao M: Bronchiectasis in pediatric AIDS. Chest. 1997, 112 (5): 1202-1207.CrossRefPubMed Sheikh S, Madiraju K, Steiner P, Rao M: Bronchiectasis in pediatric AIDS. Chest. 1997, 112 (5): 1202-1207.CrossRefPubMed
3.
go back to reference Sanders C: The radiographic diagnosis of emphysema. Radiol Clin North Am. 1991, 29 (5): 1019-1030.PubMed Sanders C: The radiographic diagnosis of emphysema. Radiol Clin North Am. 1991, 29 (5): 1019-1030.PubMed
5.
go back to reference Gotway MB, Marder SR, Hanks DK, Leung JW, Dawn SK, Gean AD, Reddy GP, Araoz PA, Webb WR: Thoracic complications of illicit drug use: an organ system approach. Radiographics. 2002, 22 Spec No: S119-35.CrossRefPubMed Gotway MB, Marder SR, Hanks DK, Leung JW, Dawn SK, Gean AD, Reddy GP, Araoz PA, Webb WR: Thoracic complications of illicit drug use: an organ system approach. Radiographics. 2002, 22 Spec No: S119-35.CrossRefPubMed
6.
go back to reference Corbett EL, Marston B, Churchyard GJ, De Cock KM: Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment. Lancet. 2006, 367 (9514): 926-937. 10.1016/S0140-6736(06)68383-9.CrossRefPubMed Corbett EL, Marston B, Churchyard GJ, De Cock KM: Tuberculosis in sub-Saharan Africa: opportunities, challenges, and change in the era of antiretroviral treatment. Lancet. 2006, 367 (9514): 926-937. 10.1016/S0140-6736(06)68383-9.CrossRefPubMed
7.
go back to reference Diaz PT, Clanton TL, Pacht ER: Emphysema-like pulmonary disease associated with human immunodeficiency virus infection. Ann Intern Med. 1992, 116 (2): 124-128.CrossRefPubMed Diaz PT, Clanton TL, Pacht ER: Emphysema-like pulmonary disease associated with human immunodeficiency virus infection. Ann Intern Med. 1992, 116 (2): 124-128.CrossRefPubMed
8.
go back to reference Yearsley MM, Diaz PT, Knoell D, Nuovo GJ: Correlation of HIV-1 detection and histology in AIDS-associated emphysema. Diagn Mol Pathol. 2005, 14 (1): 48-52. 10.1097/01.pas.0000142168.72253.11.CrossRefPubMed Yearsley MM, Diaz PT, Knoell D, Nuovo GJ: Correlation of HIV-1 detection and histology in AIDS-associated emphysema. Diagn Mol Pathol. 2005, 14 (1): 48-52. 10.1097/01.pas.0000142168.72253.11.CrossRefPubMed
9.
go back to reference McGuinness G, Naidich DP, Garay S, Leitman BS, McCauley DI: AIDS associated bronchiectasis: CT features. J Comput Assist Tomogr. 1993, 17 (2): 260-6. 10.1097/00004728-199303000-00014.CrossRefPubMed McGuinness G, Naidich DP, Garay S, Leitman BS, McCauley DI: AIDS associated bronchiectasis: CT features. J Comput Assist Tomogr. 1993, 17 (2): 260-6. 10.1097/00004728-199303000-00014.CrossRefPubMed
10.
go back to reference Silva CI, Flint JD, Levy RD, Muller NL: Diffuse lung cysts in lymphoid interstitial pneumonia: high-resolution CT and pathologic findings. J Thorac Imaging. 2006, 21 (3): 241-244. 10.1097/01.rti.0000213554.61752.73.CrossRefPubMed Silva CI, Flint JD, Levy RD, Muller NL: Diffuse lung cysts in lymphoid interstitial pneumonia: high-resolution CT and pathologic findings. J Thorac Imaging. 2006, 21 (3): 241-244. 10.1097/01.rti.0000213554.61752.73.CrossRefPubMed
11.
go back to reference Massaro D, Massaro GD: Hunger disease and pulmonary alveoli. Am J Respir Crit Care Med. 2004, 170 (7): 723-724. 10.1164/rccm.2408002.CrossRefPubMed Massaro D, Massaro GD: Hunger disease and pulmonary alveoli. Am J Respir Crit Care Med. 2004, 170 (7): 723-724. 10.1164/rccm.2408002.CrossRefPubMed
12.
go back to reference Ambrus JL, Ambrus JL: Nutrition and infectious diseases in developing countries and problems of acquired immunodeficiency syndrome. Exp Biol Med (Maywood). 2004, 229 (6): 464-472. Ambrus JL, Ambrus JL: Nutrition and infectious diseases in developing countries and problems of acquired immunodeficiency syndrome. Exp Biol Med (Maywood). 2004, 229 (6): 464-472.
13.
go back to reference van der Valk P, Monninkhof E, van der Palen J, Zielhuis G, van Herwaarden C: Management of stable COPD. Patient Educ Couns. 2004, 52 (3): 225-229. 10.1016/S0738-3991(03)00095-8.CrossRefPubMed van der Valk P, Monninkhof E, van der Palen J, Zielhuis G, van Herwaarden C: Management of stable COPD. Patient Educ Couns. 2004, 52 (3): 225-229. 10.1016/S0738-3991(03)00095-8.CrossRefPubMed
14.
go back to reference Keller DW, Breiman RF: Preventing bacterial respiratory tract infections among persons infected with human immunodeficiency virus. Clin Infect Dis. 1995, 21 (Suppl 1): S77-83.CrossRefPubMed Keller DW, Breiman RF: Preventing bacterial respiratory tract infections among persons infected with human immunodeficiency virus. Clin Infect Dis. 1995, 21 (Suppl 1): S77-83.CrossRefPubMed
15.
go back to reference Naunheim KS, Wood DE, Mohsenifar Z, Sternberg AL, Criner GJ, DeCamp MM, Deschamps CC, Martinez FJ, Sciurba FC, Tonascia J, Fishman AP: Long-term follow-up of patients receiving lung-volume-reduction surgery versus medical therapy for severe emphysema by the National Emphysema Treatment Trial Research Group. Ann Thorac Surg. 2006, 82 (2): 431-443. 10.1016/j.athoracsur.2006.05.069.CrossRefPubMed Naunheim KS, Wood DE, Mohsenifar Z, Sternberg AL, Criner GJ, DeCamp MM, Deschamps CC, Martinez FJ, Sciurba FC, Tonascia J, Fishman AP: Long-term follow-up of patients receiving lung-volume-reduction surgery versus medical therapy for severe emphysema by the National Emphysema Treatment Trial Research Group. Ann Thorac Surg. 2006, 82 (2): 431-443. 10.1016/j.athoracsur.2006.05.069.CrossRefPubMed
Metadata
Title
Pulmonary cystic disease in HIV positive individuals in the Democratic Republic of Congo: three case reports
Authors
Steven F. J. Callens
Faustin Kitetele
Patricia Lelo
Nicole Shabani
Jean Lusiama
Okitolanda Wemakoy
Robert Colebunders
Frieda Behets
Annelies Van Rie
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Journal of Medical Case Reports / Issue 1/2007
Electronic ISSN: 1752-1947
DOI
https://doi.org/10.1186/1752-1947-1-101

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