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BioPsychoSocial Medicine
Published in: BioPsychoSocial Medicine 1/2014

Open Access 01-12-2014 | Short report

High correlation between salivary cortisol awakening response and the psychometric profiles of healthy children

Authors: Ikuhiko Shibuya, Shinichiro Nagamitsu, Hisayoshi Okamura, Shuichi Ozono, Hiromi Chiba, Takashi Ohya, Yushiro Yamashita, Toyojiro Matsuishi

Published in: BioPsychoSocial Medicine | Issue 1/2014

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Abstract

Background

Cortisol awakening response (CAR) as an indicator of psychological stress and related physical and psychiatric diseases has attracted growing attention from researchers. Although CAR changes have been investigated extensively in children with behavioral and psychiatric disorders, the association between CAR and conventional psychometric scales for healthy children has not been reported. The aim of this study was to investigate the association between salivary CAR and subscales of Profiles of Mood States (POMS), a self-assessment questionnaire widely used to evaluate the temporal emotional states of healthy children.

Findings

This study included 18 healthy girls aged 13–16 years. Saliva was collected immediately on awakening, 30 min and 60 min after waking, and then at 2-hour intervals from 9 am to 5 pm. The current mood state, including depression, anxiety, fatigue, and other psychometric profiles were assessed using POMS. The magnitude of salivary CAR and the area under the concentration-time curve (AUC) for diurnal salivary cortisol were compared with the profiles. There were significant positive correlations between the magnitude of CAR and the POMS subscales for "Depression-Dejection", "Tension-Anxiety", "Fatigue", and "Confusion". No correlation was found between the AUC salivary cortisol level and the psychometric profiles.

Conclusions

Salivary CAR was associated with various mood states of healthy female children but diurnal salivary cortisol AUC was not. Salivary CAR may be a biomarker of the physical and mental condition of healthy female children.
Appendix
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Metadata
Title
High correlation between salivary cortisol awakening response and the psychometric profiles of healthy children
Authors
Ikuhiko Shibuya
Shinichiro Nagamitsu
Hisayoshi Okamura
Shuichi Ozono
Hiromi Chiba
Takashi Ohya
Yushiro Yamashita
Toyojiro Matsuishi
Publication date
01-12-2014
Publisher
BioMed Central
Published in
BioPsychoSocial Medicine / Issue 1/2014
Electronic ISSN: 1751-0759
DOI
https://doi.org/10.1186/1751-0759-8-9

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