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Journal of Cardiothoracic Surgery

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Open Access 01-12-2011 | Research article

Surgical treatment for pulmonary metastases from esophageal carcinoma after definitive chemoradiotherapy: Experience from a single institution

Authors: Yoshiki Kozu, Hiroshi Sato, Yasuhiro Tsubosa, Hirofumi Ogawa, Hirofumi Yasui, Haruhiko Kondo

Published in: Journal of Cardiothoracic Surgery | Issue 1/2011

Abstract

Background

Surgical treatment for pulmonary metastases is known to be a safe and potentially curative procedure for various primary malignancies. However, there are few reports regarding the prognostic role of surgical treatment for pulmonary metastases from esophageal carcinoma, especially after definitive chemoradiotherapy (CRT).

Methods

We retrospectively reviewed 5 patients who underwent surgical treatment for pulmonary metastases from esophageal carcinoma at our institution. The primary treatment for esophageal carcinoma was definitive CRT, and a complete response (CR) was achieved in all patients.

Results

The surgical procedure for pulmonary metastases was wedge resection, and pathological complete resection was achieved in all 5 patients. The disease free interval after definitive CRT varied from 7 to 36 months, with a median of 19 months. There were no perioperative complications, but postoperative respiratory failure occurred in 1 patient. The postoperative hospital stay varied from 4 to 7 days, with a median of 6 days. Three patients are now alive with a good performance status (PS) and are disease free. The other 2 patients died of primary disease. The overall survival after surgical treatment varied from 20 to 90 months, with a median of 29 months.

Conclusions

Surgical treatment should be considered for patients with pulmonary metastases from esophageal carcinoma who previously received CRT and achieved a CR, because it provides not only a longer survival, but also a good postoperative PS for some patients.

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Title: Surgical treatment for pulmonary metastases from esophageal carcinoma after definitive chemoradiotherapy: Experience from a single institution
Authors: Yoshiki Kozu
Hiroshi Sato
Yasuhiro Tsubosa
Hirofumi Ogawa
Hirofumi Yasui
Haruhiko Kondo
Publication date: 01-12-2011
Publisher: BioMed Central
Published in: Journal of Cardiothoracic Surgery / Issue 1/2011
Electronic ISSN: 1749-8090
DOI: https://doi.org/10.1186/1749-8090-6-135

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Surgical treatment for pulmonary metastases from esophageal carcinoma after definitive chemoradiotherapy: Experience from a single institution

Abstract

Background

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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