Published in:
Open Access 01-12-2007 | Letters to the Editor
Fixation artefact in an intra-operative frozen section: a potential cause of misinterpretation
Published in: Journal of Cardiothoracic Surgery | Issue 1/2007
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The intra-operative histological assessment of fresh tissue can provide valuable diagnostic information and guide surgical management, however, even a limited exposure to standard fixation agents can potentially compromise analysis. Defined handling strategies should exist to facilitate the receipt of all specimens, in their optimal state, by the laboratory.