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World Journal of Emergency Surgery
Published in: World Journal of Emergency Surgery 1/2009

Open Access 01-12-2009 | Review

ATLS® and damage control in spine trauma

Authors: Oliver I Schmidt, Ralf H Gahr, Andreas Gosse, Christoph E Heyde

Published in: World Journal of Emergency Surgery | Issue 1/2009

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Abstract

Substantial inflammatory disturbances following major trauma have been found throughout the posttraumatic course of polytraumatized patients, which was confirmed in experimental models of trauma and in vitro settings. As a consequence, the principle of damage control surgery (DCS) has developed over the last two decades and has been successfully introduced in the treatment of severely injured patients. The aim of damage control surgery and orthopaedics (DCO) is to limit additional iatrogenic trauma in the vulnerable phase following major injury. Considering traumatic brain and acute lung injury, implants for quick stabilization like external fixators as well as decided surgical approaches with minimized potential for additional surgery-related impairment of the patient's immunologic state have been developed and used widely. It is obvious, that a similar approach should be undertaken in the case of spinal trauma in the polytraumatized patient. Yet, few data on damage control spine surgery are published to so far, controlled trials are missing and spinal injury is addressed only secondarily in the broadly used ATLS® polytrauma algorithm. This article reviews the literature on spine trauma assessment and treatment in the polytrauma setting, gives hints on how to assess the spine trauma patient regarding to the ATLS® protocol and recommendations on therapeutic strategies in spinal injury in the polytraumatized patient.
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Literature
1.
Rotstein OD: Modeling the two-hit hypothesis for evaluating strategies to prevent organ injury after shock/resuscitation. J Trauma. 2003, 54: S203-206.PubMed
2.
Keel M, Trentz O: Pathophysiology of polytrauma. Injury. 2005, 36: 691-709.PubMed
3.
Hildebrand F, Pape HC, Krettek C: [The importance of cytokines in the posttraumatic inflammatory reaction]. Unfallchirurg. 2005, 108: 793-794.PubMed
4.
Yao YM, Redl H, Bahrami S, Schlag G: The inflammatory basis of trauma/shock-associated multiple organ failure. Inflamm Res. 1998, 47: 201-210.PubMed
5.
Menger MD, Vollmar B: Surgical trauma: hyperinflammation versus immunosuppression?. Langenbecks Arch Surg. 2004, 389: 475-484.PubMed
6.
Ni Choileain N, Redmond HP: Cell response to surgery. Arch Surg. 2006, 141: 1132-1140.PubMed
7.
Waydhas C, Nast-Kolb D, Kick M, Richter-Turtur M, Trupka A, Machleidt W, Jochum M, Schweiberer L: [Operative injury in spinal surgery in the management of polytrauma patients]. Unfallchirurg. 1993, 96: 62-65.PubMed
8.
Flohe S, Flohe SB, Schade FU, Waydhas C: Immune response of severely injured patients – influence of surgical intervention and therapeutic impact. Langenbecks Arch Surg. 2007, 392: 639-648.PubMed
9.
Flohe S, Lendemans S, Schade FU, Kreuzfelder E, Waydhas C: Influence of surgical intervention in the immune response of severely injured patients. Intensive Care Med. 2004, 30: 96-102.PubMed
10.
Bone LB, Johnson KD, Weigelt J, Scheinberg R: Early versus delayed stabilization of femoral fractures. A prospective randomized study. J Bone Joint Surg Am. 1989, 71: 336-340.PubMed
11.
Bone LB, Johnson KD, Weigelt J, Scheinberg R: Early versus delayed stabilization of femoral fractures: a prospective randomized study. 1989. Clin Orthop Relat Res. 2004, 11-16.
12.
Johnson KD, Cadambi A, Seibert GB: Incidence of adult respiratory distress syndrome in patients with multiple musculoskeletal injuries: effect of early operative stabilization of fractures. J Trauma. 1985, 25: 375-384.PubMed
13.
Waydhas C, Nast-Kolb D, Trupka A, Zettl R, Kick M, Wiesholler J, Schweiberer L, Jochum M: Posttraumatic inflammatory response, secondary operations, and late multiple organ failure. J Trauma. 1996, 40: 624-630. discussion 630-621.PubMed
14.
Harwood PJ, Giannoudis PV, van Griensven M, Krettek C, Pape HC: Alterations in the systemic inflammatory response after early total care and damage control procedures for femoral shaft fracture in severely injured patients. J Trauma. 2005, 58: 446-452. discussion 452-444.PubMed
15.
Pape HC, Grimme K, Van Griensven M, Sott AH, Giannoudis P, Morley J, Roise O, Ellingsen E, Hildebrand F, Wiese B, Krettek C: Impact of intramedullary instrumentation versus damage control for femoral fractures on immunoinflammatory parameters: prospective randomized analysis by the EPOFF Study Group. J Trauma. 2003, 55: 7-13.PubMed
16.
Pape H, Stalp M, Dahlweid M, Regel G, Tscherne H: [Optimal duration of primary surgery with regards to a "Borderline"-situation in polytrauma patients. Arbeitsgemeinschaft "Polytrauma" der Deutschen Gesellschaft fur Unfallchirurgie]. Unfallchirurg. 1999, 102: 861-869.PubMed
17.
Roberts CS, Pape HC, Jones AL, Malkani AL, Rodriguez JL, Giannoudis PV: Damage control orthopaedics: evolving concepts in the treatment of patients who have sustained orthopaedic trauma. Instr Course Lect. 2005, 54: 447-462.PubMed
18.
Scalea TM, Boswell SA, Scott JD, Mitchell KA, Kramer ME, Pollak AN: External fixation as a bridge to intramedullary nailing for patients with multiple injuries and with femur fractures: damage control orthopedics. J Trauma. 2000, 48: 613-621. discussion 621-613.PubMed
19.
Pape HC: Effects of changing strategies of fracture fixation on immunologic changes and systemic complications after multiple trauma: Damage control orthopedic surgery. J Orthop Res. 2008, 26: 1478-1484.PubMed
20.
Nast-Kolb D, Ruchholtz S, Waydhas C, Schmidt B, Taeger G: [Damage control orthopedics]. Unfallchirurg. 2005, 108: 806-811.
21.
Laurer H, Maier B, El Salman A, Lehnert M, Wygen H, Marzi I: Distribution of Spinal and Associated Injuries in Multiple Trauma Patients. Eur J Trauma Emerg Surg. 2007, 33: 476-481.
22.
Berne JD, Velmahos GC, El-Tawil Q, Demetriades D, Asensio JA, Murray JA, Cornwell EE, Belzberg H, Berne TV: Value of complete cervical helical computed tomographic scanning in identifying cervical spine injury in the unevaluable blunt trauma patient with multiple injuries: a prospective study. J Trauma. 1999, 47: 896-902. discussion 902-893.PubMed
23.
Heyde CE, Ertel W, Kayser R: [Management of spine injuries in polytraumatized patients]. Orthopade. 2005, 34: 889-905.PubMed
24.
Blauth M, Knop C, Bastian L, Krettek C, Lange U: [Complex injuries of the spine]. Orthopade. 1998, 27: 17-31.PubMed
25.
Woltmann A, Buhren V: [Shock trauma room management of spinal injuries in the framework of multiple trauma. A systematic review of the literature]. Unfallchirurg. 2004, 107: 911-918.PubMed
26.
Buhren V: [Injuries to the thoracic and lumbar spine]. Unfallchirurg. 2003, 106: 55-68. quiz 68-59.PubMed
27.
Welkerling H, Wening JV, Langendorff HU, Jungbluth KH: [Computer-assisted data analysis of injuries of the skeletal system in polytrauma patients]. Zentralbl Chir. 1991, 116: 1263-1272.PubMed
28.
McLain RF, Benson DR: Urgent surgical stabilization of spinal fractures in polytrauma patients. Spine. 1999, 24: 1646-1654.PubMed
29.
Richter-Turtur M: [Spinal injuries in polytrauma patients]. Langenbecks Arch Chir Suppl Kongressbd. 1992, 311-315.
30.
Kossmann T, Trease L, Freedman I, Malham G: Damage control surgery for spine trauma. Injury. 2004, 35: 661-670.PubMed
31.
Patel RV, DeLong W, Vresilovic EJ: Evaluation and treatment of spinal injuries in the patient with polytrauma. Clin Orthop Relat Res. 2004, 43-54.
32.
Prasad VS, Schwartz A, Bhutani R, Sharkey PW, Schwartz ML: Characteristics of injuries to the cervical spine and spinal cord in polytrauma patient population: experience from a regional trauma unit. Spinal Cord. 1999, 37: 560-568.PubMed
33.
Buhren V: [Fractures and instability of the cervical spine]. Unfallchirurg. 2002, 105: 1049-1066.PubMed
34.
Morris CG, McCoy E: Clearing the cervical spine in unconscious polytrauma victims, balancing risks and effective screening. Anaesthesia. 2004, 59: 464-482.PubMed
35.
Morris CG, Mullan B: Clearing the cervical spine after polytrauma: implementing unified management for unconscious victims in the intensive care unit. Anaesthesia. 2004, 59: 755-761.PubMed
36.
Stahel PF, Heyde CE, Wyrwich W, Ertel W: [Current concepts of polytrauma management: from ATLS to "damage control"]. Orthopade. 2005, 34: 823-836.PubMed
37.
Haas NP, Hoffmann RF, Mauch C, von Fournier C, Sudkamp NP: The management of polytraumatized patients in Germany. Clin Orthop Relat Res. 1995, 25-35.
38.
Ruchholtz S, Zintl B, Nast-Kolb D, Waydhas C, Lewan U, Kanz KG, Schwender D, Pfeifer KJ, Schweiberer L: Improvement in the therapy of multiply injured patients by introduction of clinical management guidelines. Injury. 1998, 29: 115-129.PubMed
39.
Committee ACoS: Advanced Trauma Life Support (ATLS) for Doctors, Chicago/IL. 2004, 7
40.
Jarrar D, Chaudry IH, Wang P: Organ dysfunction following hemorrhage and sepsis: mechanisms and therapeutic approaches (Review). Int J Mol Med. 1999, 4: 575-583.PubMed
41.
Schmidt OI, Heyde CE, Ertel W, Stahel PF: Closed head injury – an inflammatory disease?. Brain Res Brain Res Rev. 2005, 48: 388-399.PubMed
42.
Stahel PF, Ertel W, Heyde CE: [Traumatic brain injury: impact on timing and modality of fracture care]. Orthopade. 2005, 34: 852-864.PubMed
43.
Baptiste DC, Fehlings MG: Update on the treatment of spinal cord injury. Prog Brain Res. 2007, 161: 217-233.PubMed
44.
Heyde CE, Tschoeke SK, Hellmuth M, Hostmann A, Ertel W, Oberholzer A: Trauma induces apoptosis in human thoracolumbar intervertebral discs. BMC Clin Pathol. 2006, 6: 5-PubMedCentralPubMed
45.
Stürmer KM, Dresing K, M B, Braun W, Lobenhoffer P, Meenen N, Sieber H, Suren E, Wittner B: Guidline Commission of the Deutsche Gesellschaft für Unfallchirurgie e.V. (DGU)/Leitlinie Polytrauma. Leitlinien für die unfallchirurgische Diagnostik und Therapie der Deutschen Gesellschaft für Unfallchirurgie e. V. Akt Traumatol. 2001, 31: 44-54.
46.
Ruchholtz S, Nast-Kolb D, Waydhas C, Schweiberer L: [The injury pattern in polytrauma. Value of information regarding accident process in clinical acute management]. Unfallchirurg. 1996, 99: 633-641.PubMed
47.
Huelke DF, O'Day J, Mendelsohn RA: Cervical injuries suffered in automobile crashes. J Neurosurg. 1981, 54: 316-322.PubMed
48.
Blackmore CC, Emerson SS, Mann FA, Koepsell TD: Cervical spine imaging in patients with trauma: determination of fracture risk to optimize use. Radiology. 1999, 211: 759-765.PubMed
49.
Blackmore CC, Ramsey SD, Mann FA, Deyo RA: Cervical spine screening with CT in trauma patients: a cost-effectiveness analysis. Radiology. 1999, 212: 117-125.PubMed
50.
Hills MW, Deane SA: Head injury and facial injury: is there an increased risk of cervical spine injury?. J Trauma. 1993, 34: 549-553. discussion 553-544.PubMed
51.
Holly LT, Kelly DF, Counelis GJ, Blinman T, McArthur DL, Cryer HG: Cervical spine trauma associated with moderate and severe head injury: incidence, risk factors, and injury characteristics. J Neurosurg. 2002, 96: 285-291.PubMed
52.
Kohler A, Friedl HP, Kach K, Stocker R, Trentz O: [Patient management in polytrauma with injuries of the cervical spine]. Helv Chir Acta. 1994, 60: 547-550.PubMed
53.
Linsenmaier U, Kanz KG, Mutschler W, Pfeifer KJ: [Radiological diagnosis in polytrauma: interdisciplinary management]. Rofo. 2001, 173: 485-493.PubMed
54.
Harris MB, Kronlage SC, Carboni PA, Robert KQ, Menmuir B, Ricciardi JE, Chutkan NB: Evaluation of the cervical spine in the polytrauma patient. Spine. 2000, 25: 2884-2891. discussion 2892.PubMed
55.
Harris MB, Waguespack AM, Kronlage S: 'Clearing' cervical spine injuries in polytrauma patients: is it really safe to remove the collar?. Orthopedics. 1997, 20: 903-907.PubMed
56.
Platzer P, Jaindl M, Thalhammer G, Dittrich S, Wieland T, Vecsei V, Gaebler C: Clearing the cervical spine in critically injured patients: a comprehensive C-spine protocol to avoid unnecessary delays in diagnosis. Eur Spine J. 2006, 15: 1801-1810.PubMed
57.
Bohlman HH: Acute fractures and dislocations of the cervical spine. An analysis of three hundred hospitalized patients and review of the literature. J Bone Joint Surg Am. 1979, 61: 1119-1142.PubMed
58.
Platzer P, Hauswirth N, Jaindl M, Chatwani S, Vecsei V, Gaebler C: Delayed or missed diagnosis of cervical spine injuries. J Trauma. 2006, 61: 150-155.PubMed
59.
Sees DW, Rodriguez Cruz LR, Flaherty SF, Ciceri DP: The use of bedside fluoroscopy to evaluate the cervical spine in obtunded trauma patients. J Trauma. 1998, 45: 768-771.PubMed
60.
Josten C, Katscher S: [Radiologic Diagnostics in Spine Trauma Patients]. Akt Traumatol. 2003, 33: 157-164.
61.
Pal JM, Mulder DS, Brown RA, Fleiszer DM: Assessing multiple trauma: is the cervical spine enough?. J Trauma. 1988, 28: 1282-1284.PubMed
62.
Nunez D: [The diagnosis of traumatic cervical lesions: a decade of evidence-based change]. Radiologia. 2006, 48: 185-187.PubMed
63.
Nunez D: Value of complete cervical helical computed tomographic scanning in identifying cervical spine injury in the unevaluable blunt trauma patient with multiple injuries: a prospective study. J Trauma. 2000, 48: 988-989.PubMed
64.
Heuchemer T, Waidelich H, Haberle HJ, Bargon G: [The diagnosis of spinal trauma: the indication for CT and myelo-CT on the day of the injury]. Rofo. 1992, 156: 156-159.PubMed
65.
Albrecht T, von Schlippenbach J, Stahel PF, Ertel W, Wolf KJ: [The role of whole body spiral CT in the primary work-up of polytrauma patients – comparison with conventional radiography and abdominal sonography]. Rofo. 2004, 176: 1142-1150.PubMed
66.
Lindner T, Bail HJ, Manegold S, Stockle U, Haas NP: [Shock trauma room diagnosis: initial diagnosis after blunt abdominal trauma. A review of the literature]. Unfallchirurg. 2004, 107: 892-902.PubMed
67.
Myers J: Focused assessment with sonography for trauma (FAST): the truth about ultrasound in blunt trauma. J Trauma. 2007, 62: S28-PubMed
68.
Deunk J, Dekker HM, Brink M, van Vugt R, Edwards MJ, van Vugt AB: The value of indicated computed tomography scan of the chest and abdomen in addition to the conventional radiologic work-up for blunt trauma patients. J Trauma. 2007, 63: 757-763.PubMed
69.
Kuhne CA, Ruchholtz S, Buschmann C, Sturm J, Lackner CK, Wentzensen A, Bouillon B, Waydhas C, Weber C: [Trauma centers in Germany. Status report]. Unfallchirurg. 2006, 109: 357-366.PubMed
70.
White AA, Panjabi MM: The Problem of Clinical Instability in the human Spine: A systemic Approach. Clinical Biomechanics of the Spine. 1990, Lippincott Williams & Wilkins, 277-378. 2
71.
Blauth M, Tscherne H: Lower Cervical Spine (Untere Halswirbelsäule). Tscherne: Unfallchirurgie Wirbelsäule. 1998, Berlin, Heidelberg, New York: Springer, 153-238.
72.
Magerl F, Aebi M, Gertzbein SD, Harms J, Nazarian S: A comprehensive classification of thoracic and lumbar injuries. Eur Spine J. 1994, 3: 184-201.PubMed
73.
Whitesides TE: Traumatic kyphosis of the thoracolumbar spine. Clin Orthop Relat Res. 1977, 78-92.
74.
Denis F, Armstrong GW, Searls K, Matta L: Acute thoracolumbar burst fractures in the absence of neurologic deficit. A comparison between operative and nonoperative treatment. Clin Orthop Relat Res. 1984, 142-149.
75.
Gertzbein SD: Scoliosis Research Society. Multicenter spine fracture study. Spine. 1992, 17: 528-540.PubMed
76.
Knight RQ, Stornelli DP, Chan DP, Devanny JR, Jackson KV: Comparison of operative versus nonoperative treatment of lumbar burst fractures. Clin Orthop Relat Res. 1993, 112-121.
77.
Resch H, Rabl M, Klampfer H, Ritter E, Povacz P: [Surgical vs. conservative treatment of fractures of the thoracolumbar transition]. Unfallchirurg. 2000, 103: 281-288.PubMed
78.
Shen WJ, Liu TJ, Shen YS: Nonoperative treatment versus posterior fixation for thoracolumbar junction burst fractures without neurologic deficit. Spine. 2001, 26: 1038-1045.PubMed
79.
Siebenga J, Leferink VJ, Segers MJ, Elzinga MJ, Bakker FC, Haarman HJ, Rommens PM, ten Duis HJ, Patka P: Treatment of traumatic thoracolumbar spine fractures: a multicenter prospective randomized study of operative versus nonsurgical treatment. Spine. 2006, 31: 2881-2890.PubMed
80.
Wood K, Buttermann G, Mehbod A, Garvey T, Jhanjee R, Sechriest V, Butterman G: Operative compared with nonoperative treatment of a thoracolumbar burst fracture without neurological deficit. A prospective, randomized study. J Bone Joint Surg Am. 2003, 85-A: 773-781.PubMed
81.
Stadhouder A, Buskens E, de Klerk LW, Verhaar JA, Dhert WA, Verbout AJ, Vaccaro AR, Oner FC: Traumatic thoracic and lumbar spinal fractures: operative or nonoperative treatment: comparison of two treatment strategies by means of surgeon equipoise. Spine. 2008, 33: 1006-1017.PubMed
82.
Roer van der N, de Lange ES, Bakker FC, de Vet HC, van Tulder MW: Management of traumatic thoracolumbar fractures: a systematic review of the literature. Eur Spine J. 2005, 14: 527-534.PubMedCentralPubMed
83.
Thomas KC, Bailey CS, Dvorak MF, Kwon B, Fisher C: Comparison of operative and nonoperative treatment for thoracolumbar burst fractures in patients without neurological deficit: a systematic review. J Neurosurg Spine. 2006, 4: 351-358.PubMed
84.
Yi L, Jingping B, Gele J, Baoleri X, Taixiang W: Operative versus non-operative treatment for thoracolumbar burst fractures without neurological deficit. Cochrane Database Syst Rev. 2006, CD005079-
85.
Moller A, Hasserius R, Redlund-Johnell I, Ohlin A, Karlsson MK: Nonoperatively treated burst fractures of the thoracic and lumbar spine in adults: a 23- to 41-year follow-up. Spine J. 2007, 7: 701-707.PubMed
86.
Josten C, Katscher S, Gonschorek O: [Treatment concepts for fractures of the thoracolumbar junction and lumbar spine]. Orthopade. 2005, 34: 1021-1032.PubMed
87.
Altay M, Ozkurt B, Aktekin CN, Ozturk AM, Dogan O, Tabak AY: Treatment of unstable thoracolumbar junction burst fractures with short- or long-segment posterior fixation in magerl type a fractures. Eur Spine J. 2007, 16: 1145-1155.PubMedCentralPubMed
88.
Knop C, Blauth M, Buhren V, Hax PM, Kinzl L, Mutschler W, Pommer A, Ulrich C, Wagner S, Weckbach A: [Surgical treatment of injuries of the thoracolumbar transition. 1: Epidemiology]. Unfallchirurg. 1999, 102: 924-935.PubMed
89.
Knop C, Fabian HF, Bastian L, Blauth M: Late results of thoracolumbar fractures after posterior instrumentation and transpedicular bone grafting. Spine. 2001, 26: 88-99.PubMed
90.
McLain RF: The biomechanics of long versus short fixation for thoracolumbar spine fractures. Spine. 2006, 31: S70-79. discussion S104.PubMed
91.
Alanay A, Yazici M, Acaroglu E, Turhan E, Cila A, Surat A: Course of nonsurgical management of burst fractures with intact posterior ligamentous complex: an MRI study. Spine. 2004, 29: 2425-2431.PubMed
92.
Schlegel J, Bayley J, Yuan H, Fredricksen B: Timing of surgical decompression and fixation of acute spinal fractures. J Orthop Trauma. 1996, 10: 323-330.PubMed
93.
Pape HC, Hildebrand F, Krettek C: [Decision making and and priorities for surgical treatment during and after shock trauma room treatment]. Unfallchirurg. 2004, 107: 927-936.PubMed
94.
95.
96.
Grass R, Biewener A, Dickopf A, Rammelt S, Heineck J, Zwipp H: [Percutaneous dorsal versus open instrumentation for fractures of the thoracolumbar border. A comparative, prospective study]. Unfallchirurg. 2006, 109: 297-305.PubMed
97.
Fehlings MG, Perrin RG: The role and timing of early decompression for cervical spinal cord injury: update with a review of recent clinical evidence. Injury. 2005, 36 (Suppl 2): B13-26.PubMed
98.
Aebi M, Mohler J, Zach GA, Morscher E: Indication, surgical technique, and results of 100 surgically-treated fractures and fracture-dislocations of the cervical spine. Clin Orthop Relat Res. 1986, 244-257.
99.
Delamarter RB, Sherman J, Carr JB: Pathophysiology of spinal cord injury. Recovery after immediate and delayed decompression. J Bone Joint Surg Am. 1995, 77: 1042-1049.PubMed
100.
Delamarter RB, Sherman JE, Carr JB: 1991 Volvo Award in experimental studies. Cauda equina syndrome: neurologic recovery following immediate, early, or late decompression. Spine. 1991, 16: 1022-1029.PubMed
101.
Dimar JR, Glassman SD, Raque GH, Zhang YP, Shields CB: The influence of spinal canal narrowing and timing of decompression on neurologic recovery after spinal cord contusion in a rat model. Spine. 1999, 24: 1623-1633.PubMed
102.
Dolan EJ, Tator CH, Endrenyi L: The value of decompression for acute experimental spinal cord compression injury. J Neurosurg. 1980, 53: 749-755.PubMed
103.
Fitch MT, Silver J: CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp Neurol. 2008, 209: 294-301.PubMedCentralPubMed
104.
Hurlbert RJ, Hamilton MG: Methylprednisolone for acute spinal cord injury: 5-year practice reversal. Can J Neurol Sci. 2008, 35: 41-45.PubMed
105.
Bracken MB: Pharmacological interventions for acute spinal cord injury. Cochrane Database Syst Rev. 2000, CD001046-
106.
Bracken MB: Steroids for acute spinal cord injury. Cochrane Database Syst Rev. 2002, CD001046-
107.
Bracken MB, Shepard MJ, Collins WF, Holford TR, Young W, Baskin DS, Eisenberg HM, Flamm E, Leo-Summers L, Maroon J: A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study. N Engl J Med. 1990, 322: 1405-1411.PubMed
108.
Bracken MB, Shepard MJ, Holford TR, Leo-Summers L, Aldrich EF, Fazl M, Fehlings M, Herr DL, Hitchon PW, Marshall LF: Administration of methylprednisolone for 24 or 48 hours or tirilazad mesylate for 48 hours in the treatment of acute spinal cord injury. Results of the Third National Acute Spinal Cord Injury Randomized Controlled Trial. National Acute Spinal Cord Injury Study. Jama. 1997, 277: 1597-1604.PubMed
109.
Apuzzo MLJ: Pharmacological therapy of acute cervical spinal cord injury. Neurosurgery. 2002, 50: 63-72.
110.
Hugenholtz H, Cass DE, Dvorak MF, Fewer DH, Fox RJ, Izukawa DM, Lexchin J, Tuli S, Bharatwal N, Short C: High-dose methylprednisolone for acute closed spinal cord injury – only a treatment option. Can J Neurol Sci. 2002, 29: 227-235.PubMed
111.
Hurlbert RJ: Methylprednisolone for acute spinal cord injury: an inappropriate standard of care. J Neurosurg. 2000, 93: 1-7.PubMed
112.
Matsumoto T, Tamaki T, Kawakami M, Yoshida M, Ando M, Yamada H: Early complications of high-dose methylprednisolone sodium succinate treatment in the follow-up of acute cervical spinal cord injury. Spine. 2001, 26: 426-430.PubMed
113.
Sayer FT, Kronvall E, Nilsson OG: Methylprednisolone treatment in acute spinal cord injury: the myth challenged through a structured analysis of published literature. Spine J. 2006, 6: 335-343.PubMed
114.
Hurlbert RJ: Strategies of medical intervention in the management of acute spinal cord injury. Spine. 2006, 31: S16-21. discussion S36.PubMed
115.
Rutges JP, Oner FC, Leenen LP: Timing of thoracic and lumbar fracture fixation in spinal injuries: a systematic review of neurological and clinical outcome. Eur Spine J. 2007, 16: 579-587.PubMedCentralPubMed
116.
Pape HC, Giannoudis P, Krettek C: The timing of fracture treatment in polytrauma patients: relevance of damage control orthopedic surgery. Am J Surg. 2002, 183: 622-629.PubMed
117.
Rotondo MF, Schwab CW, McGonigal MD, Phillips GR, Fruchterman TM, Kauder DR, Latenser BA, Angood PA: 'Damage control': an approach for improved survival in exsanguinating penetrating abdominal injury. J Trauma. 1993, 35: 375-382. discussion 382-373.PubMed
118.
Rotondo MF, Zonies DH: The damage control sequence and underlying logic. Surg Clin North Am. 1997, 77: 761-777.PubMed
119.
Davis JW, Kaups KL, Parks SN: Base deficit is superior to pH in evaluating clearance of acidosis after traumatic shock. J Trauma. 1998, 44: 114-118.PubMed
120.
Davis JW, Parks SN, Kaups KL, Gladen HE, O'Donnell-Nicol S: Admission base deficit predicts transfusion requirements and risk of complications. J Trauma. 1996, 41: 769-774.PubMed
121.
Abramson D, Scalea TM, Hitchcock R, Trooskin SZ, Henry SM, Greenspan J: Lactate clearance and survival following injury. J Trauma. 1993, 35: 584-588. discussion 588–589.PubMed
122.
Pape HC, Hildebrand F, Pertschy S, Zelle B, Garapati R, Grimme K, Krettek C, Reed RL: Changes in the management of femoral shaft fractures in polytrauma patients: from early total care to damage control orthopedic surgery. J Trauma. 2002, 53: 452-461. discussion 461-452.PubMed
123.
Giannoudis PV, Veysi VT, Pape HC, Krettek C, Smith MR: When should we operate on major fractures in patients with severe head injuries?. Am J Surg. 2002, 183: 261-267.PubMed
124.
Keel M, Labler L, Trentz O: "Damage Control" in Severely Injured Patients: Why, when, and How?. Eur J Trauma. 2005, 31: 212-221.
125.
Pape HC, van Griensven M, Rice J, Gansslen A, Hildebrand F, Zech S, Winny M, Lichtinghagen R, Krettek C: Major secondary surgery in blunt trauma patients and perioperative cytokine liberation: determination of the clinical relevance of biochemical markers. J Trauma. 2001, 50: 989-1000.PubMed
126.
Lendemans S, Kreuzfelder E, Waydhas C, Nast-Kolb D, Flohe S: [Clinical course and prognostic significance of immunological and functional parameters after severe trauma]. Unfallchirurg. 2004, 107: 203-210.PubMed
127.
Maier B, Lefering R, Lehnert M, Laurer HL, Steudel WI, Neugebauer EA, Marzi I: Early versus late onset of multiple organ failure is associated with differing patterns of plasma cytokine biomarker expression and outcome after severe trauma. Shock. 2007, 28: 668-674.PubMed
128.
Pape HC, Tsukamoto T, Kobbe P, Tarkin I, Katsoulis S, Peitzman A: Assessment of the clinical course with inflammatory parameters. Injury. 2007, 38: 1358-1364.PubMed
Metadata
Title
ATLS® and damage control in spine trauma
Authors
Oliver I Schmidt
Ralf H Gahr
Andreas Gosse
Christoph E Heyde
Publication date
01-12-2009
Publisher
BioMed Central
Published in
World Journal of Emergency Surgery / Issue 1/2009
Electronic ISSN: 1749-7922
DOI
https://doi.org/10.1186/1749-7922-4-9

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