Open Access 01-12-2009 | Review
Molecular mechanisms of traumatic brain injury: the missing link in management
Published in: World Journal of Emergency Surgery | Issue 1/2009
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Head injury is common, sometimes requires intensive care unit admission, and is associated with significant mortality and morbidity. A gap still remains in the understanding of the molecular mechanism of this condition. This review is aimed at providing a general overview of the molecular mechanisms involved in traumatic brain injury to a busy clinician. It will encompass the pathophysiology in traumatic brain injury including apoptosis, the role of molecules and genes, and a brief mention of possible pharmacological therapies.