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Open Access 01-12-2010 | Review

The role of radiotherapy in multimodal treatment of pancreatic carcinoma

Authors: Thomas B Brunner, Martin Scott-Brown

Published in: Radiation Oncology | Issue 1/2010

Abstract

Pancreatic ductal carcinoma is one of the most lethal malignancies, but in recent years a number of positive developments have occurred in the management of pancreatic carcinoma. This article aims to give an overview of the current knowledge regarding the role of radiotherapy in the treatment of pancreatic ductal adenocarcinoma (PDAC). The results of meta-analyses, phase III-studies, and phase II-studies using chemoradiotherapy and chemotherapy for resectable and non-resectable PDAC were reviewed. The use of radiotherapy is discussed in the neoadjuvant and adjuvant settings as well as in the locally advanced situation. Whenever possible, radiotherapy should be performed as simultaneous chemoradiotherapy. Patients with PDAC should be offered entry into clinical trials to identify optimal treatment results.

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Title: The role of radiotherapy in multimodal treatment of pancreatic carcinoma
Authors: Thomas B Brunner
Martin Scott-Brown
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2010
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-5-64

At a glance: The STEP trials

Springer Medicine

The role of radiotherapy in multimodal treatment of pancreatic carcinoma

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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