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Open Access 01-12-2010 | Research

Dosimetric precision of an ion beam tracking system

Authors: Christoph Bert, Alexander Gemmel, Nami Saito, Naved Chaudhri, Dieter Schardt, Marco Durante, Gerhard Kraft, Eike Rietzel

Published in: Radiation Oncology | Issue 1/2010

Abstract

Background

Scanned ion beam therapy of intra-fractionally moving tumors requires motion mitigation. GSI proposed beam tracking and performed several experimental studies to analyse the dosimetric precision of the system for scanned carbon beams.

Methods

A beam tracking system has been developed and integrated in the scanned carbon ion beam therapy unit at GSI. The system adapts pencil beam positions and beam energy according to target motion.

Motion compensation performance of the beam tracking system was assessed by measurements with radiographic films, a range telescope, a 3D array of 24 ionization chambers, and cell samples for biological dosimetry. Measurements were performed for stationary detectors and moving detectors using the beam tracking system.

Results

All detector systems showed comparable data for a moving setup when using beam tracking and the corresponding stationary setup. Within the target volume the mean relative differences of ionization chamber measurements were 0.3% (1.5% standard deviation, 3.7% maximum). Film responses demonstrated preserved lateral dose gradients. Measurements with the range telescope showed agreement of Bragg peak depth under motion induced range variations. Cell survival experiments showed a mean relative difference of -5% (-3%) between measurements and calculations within the target volume for beam tracking (stationary) measurements.

Conclusions

The beam tracking system has been successfully integrated. Full functionality has been validated dosimetrically in experiments with several detector types including biological cell systems.

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Title: Dosimetric precision of an ion beam tracking system
Authors: Christoph Bert
Alexander Gemmel
Nami Saito
Naved Chaudhri
Dieter Schardt
Marco Durante
Gerhard Kraft
Eike Rietzel
Publication date: 01-12-2010
Publisher: BioMed Central
Published in: Radiation Oncology / Issue 1/2010
Electronic ISSN: 1748-717X
DOI: https://doi.org/10.1186/1748-717X-5-61

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Dosimetric precision of an ion beam tracking system

Abstract

Background

Methods

Results

Conclusions

At a glance: The ONWARDS insulin icodec trials

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

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