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Radiation Oncology
Published in: Radiation Oncology 1/2010

Open Access 01-12-2010 | Research

Evaluation of volumetric modulated arc therapy (VMAT) with Oncentra MasterPlan® for the treatment of head and neck cancer

Authors: Judith Alvarez-Moret, Fabian Pohl, Oliver Koelbl, Barbara Dobler

Published in: Radiation Oncology | Issue 1/2010

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Abstract

Background

Several comparison studies have shown the capability of VMAT to achieve similar or better plan quality as IMRT, while reducing the treatment time. The experience of VMAT in a multi vendor environment is limited. We compared the plan quality and performance of VMAT to IMRT and we investigate the effects of varying various user-selectable parameters.

Methods

IMRT, single arc VMAT and dual arc VMAT were compared for four different head-and-neck tumors. For VMAT, the effect of varying gantry angle spacing and treatment time on the plan quality was investigated. A comparison of monitor units and treatment time was performed.

Results

IMRT and dual arc VMAT achieved a similar plan quality, while single arc could not provide an acceptable plan quality. Increasing the number of control points does not improve the plan quality. Dual arc VMAT delivery time is about 30% of IMRT delivery time.

Conclusions

Dual arc VMAT is a fast and accurate technique for the treatment of head and neck cancer. It applies similar number of MUs as IMRT, but the treatment time is strongly reduced, maintaining similar or better dose conformity to the PTV and OAR sparing.
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Literature
1.
Lin A, Kim HM, Terrell JE, Dawson LA, Ship JA, Eisbruch A: Quality of life after parotid-sparing IMRT for head-and-neck cancer: a prospective longitudinal study. Int J Radiat Oncol Biol Phys 2003, 57: 61-70. 10.1016/S0360-3016(03)00361-4CrossRefPubMed
2.
Dirix P, Nuyts S, Van den Bogaert W: Radiation-induced xerostomia in patients with head and neck cancer: a literature review. Cancer 2006, 107: 2525-2534. 10.1002/cncr.22302CrossRefPubMed
3.
Fang FM, Tsai WL, Chen HC, Hsu HC, Hsiung CY, Chien CY, Ko SF: Intensity-modulated or conformal radiotherapy improves the quality of life of patients with nasopharyngeal carcinoma: comparisons of four radiotherapy techniques. Cancer 2007, 109: 313-321. 10.1002/cncr.22396CrossRefPubMed
4.
Chao KS, Majhail N, Huang CJ, Simpson JR, Perez CA, Haughey B, Spector G: Intensity-modulated radiation therapy reduces late salivary toxicity without compromising tumor control in patients with oropharyngeal carcinoma: a comparison with conventional techniques. Radiother Oncol 2001, 61: 275-280. 10.1016/S0167-8140(01)00449-2CrossRefPubMed
5.
McMillan AS, Pow EH, Kwong DL, Wong MC, Sham JS, Leung LH, Leung WK: Preservation of quality of life after intensity-modulated radiotherapy for early-stage nasopharyngeal carcinoma: results of a prospective longitudinal study. Head Neck 2006, 28: 712-722. 10.1002/hed.20378CrossRefPubMed
6.
Otto K: Volumetric modulated arc therapy: IMRT in a single arc. Med phys 2008, 35: 310-317. 10.1118/1.2818738CrossRefPubMed
7.
Oliver M, Ansbacher W, Beckham WA: Comparing planning time, delivery time and plan quality for IMRT, RapidArc and Tomotherapy. J Appl Clin Med Phys 2009,10(4):3068. 10.1120/jacmp.v10i4.3068CrossRefPubMed
8.
Clivio A, Fogliata A, Franzetti-Pellanda A, Nicolini G, Vanetti E, Wyttenbach R, Cozzi L: Volumetric-modulated arc radiotherapy for carcinomas of the anal canal: A treatment planning comparison with fixed field IMRT. Radiother Oncol 2009,92(1):118-24. 10.1016/j.radonc.2008.12.020CrossRefPubMed
9.
Vanetti E, Clivio A, Nicolini G, Fogliata A, Ghosh-Laskar S, Agarwal JP, Upreti RR, Budrukkar A, Murthy V, Deshpande DD, Shrivastava SK, Dinshaw KA, Cozzi L: Volumetric modulated arc radiotherapy for carcinomas of the oro-pharynx, hypo-pharynx and larynx: a treatment planning comparison with fixed field IMRT. Radiother Oncol 2009,92(1):111-7. 10.1016/j.radonc.2008.12.008CrossRefPubMed
10.
Palma D, Vollans E, James K, Nakano S, Moiseenko V, Shaffer R, McKenzie M, Morris J, Otto K: Volumetric arc therapy for delivery of prostate radiotherapy: comparison with intensity modulated radiotherapy and three-dimensional conformal radiotherapy. Int J Radiat Oncol Biol Phys 2008,72(4):996-1001. 10.1016/j.ijrobp.2008.02.047CrossRefPubMed
11.
Wolff D, Stieler F, Hermann B, Heim K, Clausen S, Fleckenstein J, Polednik M, Steil V, Wenz F, Lohr F: Clinical implementation of volumetric intensity-modulated arc therapy (VMAT) with ERGO++. Strahlenther Onkol 2010, 186: 280-8. 10.1007/s00066-010-2071-zCrossRefPubMed
12.
Haga A, Nakagawa K, Shiraishi K, Itoh S, Terahara A, Yamashita H, Ohtomo K, Saegusa S, Imae T, Yoda K, Pellegrini R: Quality assurance of volumetric modulated arc therapy using Elekta Synergy. Acta Oncol 2009, 48: 1993-7. 10.3109/02841860903081905CrossRef
13.
Yoo S, Wu QJ, Lee WR, Yin FF: Radiotherapy treatment plans with RapidArc for prostate cancer involving seminal vesicles and lymph nodes. Int J Radiat Oncol Biol Phys 2010,76(3):935-42. Epub 10.1016/j.ijrobp.2009.07.1677CrossRefPubMed
14.
Popescu CC, Olivotto IA, Beckham WA, Ansbacher W, Zaygorodni S, Shaffer R, Wai ES, Otto K: Volumetric modulated arc therapy improves dosimetry and reduces treatment time compared to conventional intensity-modulated radiotherapy for locoregional radiotherapy of left-sided breast cancer and internal mammary nodes. Int J Radiat Oncol Biol Phys 2010,76(1):287-95. 10.1016/j.ijrobp.2009.05.038CrossRefPubMed
15.
Guckenberger M, Richter A, Krieger T, Wilbert J, Baier K, Flentje M: Is a single arc sufficient in volumetric-modulated arc therapy (VMAT) for complex-shaped target volumes? Radiother Oncol 2009, 93: 259-65. 10.1016/j.radonc.2009.08.015CrossRefPubMed
16.
Tsai CL, Wu JK, Chao HL, Tsai YC, Cheng JC: Treatment and dosimetric advantages between VMAT, IMRT and Helical Tomotherapy in Prostate Cancer. Med Dosim 2010.
17.
Pesce GA, Clivio A, Cozzi L, Nicolini G, Richetti A, Salati E, Valli M, Vanetti E, Fogliata A: Early clinical experience of radiotherapy of prostate cancer with volumetric modulated arc therapy. Radiat Oncol 2010, 5: 54. 10.1186/1748-717X-5-54PubMedCentralCrossRefPubMed
18.
Doornaert P, Verbakel WF, Bieker M, Slotman BJ, Senan S: RapidArc planning and delivery in patients with locally advanced head-and-neck cancer undergoing chemotherapy. Int J Radiat Oncol Biol Phys 2010, in press.
19.
Verbakel WF, Cuijpers JP, Hoffmans D, Bieker M, Slotman BJ, Senan S: Volumetric intensity-modulated arc therapy vs. conventional IMRT in head-and-neck cancer: a comparative planning and dosimetric study. Int J Radiat Oncol Biol Phys 2009,74(1):252-9. 10.1016/j.ijrobp.2008.12.033CrossRefPubMed
20.
Wu QJ, Yoo S, Kirkpatrick JP, Thongphiew D, Yin FF: Volumetric arc intensity-modulated therapy for spine body radiotherapy: comparison with static intensity-modulated treatment. Int J Radiat Oncol Biol Phys 2009,75(5):1596-604. 10.1016/j.ijrobp.2009.05.005CrossRefPubMed
21.
Bertelsen A, Hansen CR, Johansen J, Brink C: Single Arc Volumetric Modulated Arc Therapy of head and neck cancer. Radiother Oncol 2010,95(2):142-8. 10.1016/j.radonc.2010.01.011CrossRefPubMed
22.
Treutwein M, Hipp M, Koelbl O, Bogner L: IMRT of prostate cancer: a comparison of fluence optimization with sequencial segmentation and direct step-and-shoot optimization. Strahlenther Onkol 2009,185(6):379-83. 10.1007/s00066-009-1950-7CrossRefPubMed
23.
Dobler B, Pohl F, Bogner L, Koelbl O: Comparison of direct machine parameter optimization versus fluence optimization with sequential sequencing in IMRT of hypopharyngeal carcinoma. Radiat Oncol 2007,6(2):33. 10.1186/1748-717X-2-33CrossRef
24.
Dobler B, Koelbl O, Bogner L, Pohl F: Direct machine parameter optimization for intensity modulated radiation therapy (IMRT) of oropharyngeal cancer - a planning study. J Appl Clin Med Phys 2009,10(4):3066. 10.1120/jacmp.v10i4.3066CrossRefPubMed
25.
Bzudesek K, Friberger H, Eriksson K, Hårdermark B, Robinson D, Kaus M: Development and evaluation of an efficient approach to volumetric arc therapy planning. Med Phys 2009,36(6):2328-39. 10.1118/1.3132234CrossRef
26.
Dobler B, Streck N, Klein E, Loeschel R, Haertl P, Koelbl O: Hybrid plan verification for intensity-modulated radiation therapy (IMRT) using the 2 D ionization chamber array I'mRT MatriXX--a feasibility study. Phys Med Biol 2010, 55: 39-55. 10.1088/0031-9155/55/2/N02CrossRef
27.
McGrath SD, Mathuszak MM, Yan D, Kestin LL, Martinez AA, Grills IS: Volumetric modulated arc therapy for delivery of hypofractionated stereotactic lung radiotherapy: A dosimetric and treatment efficiency analysis. Radiother Oncol 2010,95(2):153-7. 10.1016/j.radonc.2009.12.039CrossRefPubMed
28.
Feygelman V, Zhang G, Stevens C: Initial dosimetric evaluation of SmartArc - a novel VMAT treatment planning module implemented in a multi-vendor delivery chain. J Appl Clin Med Phys 2010,11(1):3169.PubMed
Metadata
Title
Evaluation of volumetric modulated arc therapy (VMAT) with Oncentra MasterPlan® for the treatment of head and neck cancer
Authors
Judith Alvarez-Moret
Fabian Pohl
Oliver Koelbl
Barbara Dobler
Publication date
01-12-2010
Publisher
BioMed Central
Published in
Radiation Oncology / Issue 1/2010
Electronic ISSN: 1748-717X
DOI
https://doi.org/10.1186/1748-717X-5-110

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