Skip to main content
Top
Published in: Diagnostic Pathology 1/2006

Open Access 01-12-2006 | Case Report

Malignancy in the blind painful eye – report of two cases and literature review

Authors: Patrícia Rusa Pereira, Alexandre Nakao Odashiro, João Pessoa Souza Filho, Vinicius S Saraiva, David Gerardo Camoriano, Miguel N Burnier Jr

Published in: Diagnostic Pathology | Issue 1/2006

Login to get access

Abstract

Background

Few cases of malignant tumors arising in a blind painful eye have previously been described. We described two cases of a blind painful eye containing an unsuspected tumor, which were enucleated to relieve the pain.

Case presentations

Case 1: A 57 year-old Caucasian man presented with recurrent orbital cellulitis and endophthalmitis in the left eye (OS). The OS was blind and painful and an enucleation was performed showing a uveal melanoma by histopathological exam. Case 2: A 54 year-old Caucasian man with previous history of a rhegmatogenous retinal detachment in his left eye presented a blind painful eye. Enucleation was performed revealing a well-differentiated B-cell lymphoma of uveal tract with extra ocular extension.

Conclusion

In the management of a blind painful eye, it is extremely important to rule out an intraocular malignancy particularly in those patients who have not been followed by an ophthalmologist.
Appendix
Available only for authorised users
Literature
1.
go back to reference Custer PL, Reistad CE: Enucleation of blind, painful eyes. Ophthal Plast Reconstr Surg. 2000, 16: 326-329. 10.1097/00002341-200009000-00004.CrossRefPubMed Custer PL, Reistad CE: Enucleation of blind, painful eyes. Ophthal Plast Reconstr Surg. 2000, 16: 326-329. 10.1097/00002341-200009000-00004.CrossRefPubMed
2.
go back to reference Edelstein C, Shields CL, Shields JA, Eagle RC: Presumed adenocarcinoma of the retinal pigment epithelium in a blind eye with a staphyloma. Arch Ophthalmol. 1998, 116: 525-528.CrossRefPubMed Edelstein C, Shields CL, Shields JA, Eagle RC: Presumed adenocarcinoma of the retinal pigment epithelium in a blind eye with a staphyloma. Arch Ophthalmol. 1998, 116: 525-528.CrossRefPubMed
3.
go back to reference Loeffler KU, Kivela T, Borgmann H, Witschel H: Malignant tumor of the retinal pigment epithelium with extraocular extension in a phthisical eye. Graefes Arch Clin Exp Ophthalmol. 1996, 234 Suppl 1: S70-5. 10.1007/BF02343051.CrossRefPubMed Loeffler KU, Kivela T, Borgmann H, Witschel H: Malignant tumor of the retinal pigment epithelium with extraocular extension in a phthisical eye. Graefes Arch Clin Exp Ophthalmol. 1996, 234 Suppl 1: S70-5. 10.1007/BF02343051.CrossRefPubMed
4.
go back to reference Nelson CC, Kincaid MC: Extrascleral malignant melanoma. Ophthal Plast Reconstr Surg. 1992, 8: 56-61.CrossRefPubMed Nelson CC, Kincaid MC: Extrascleral malignant melanoma. Ophthal Plast Reconstr Surg. 1992, 8: 56-61.CrossRefPubMed
5.
go back to reference Sarma DP, Deshotels SJ, Lunseth JH: Malignant melanoma in a blind eye. J Surg Oncol. 1983, 23: 169-172.CrossRefPubMed Sarma DP, Deshotels SJ, Lunseth JH: Malignant melanoma in a blind eye. J Surg Oncol. 1983, 23: 169-172.CrossRefPubMed
7.
go back to reference Tripathi A, Hiscott P, Damato BE: Malignant melanoma and massive retinal gliosis in phthisis bulbi. Eye. 2002, 16: 781-782. 10.1038/sj.eye.6700217.CrossRefPubMed Tripathi A, Hiscott P, Damato BE: Malignant melanoma and massive retinal gliosis in phthisis bulbi. Eye. 2002, 16: 781-782. 10.1038/sj.eye.6700217.CrossRefPubMed
8.
go back to reference Zimmerman LE: Problems in the diagnosis of malignant melanomas of the choroid and ciliary body. The 1972 Arthur J. Bedell Lecture. Am J Ophthalmol. 1973, 75: 917-929.CrossRefPubMed Zimmerman LE: Problems in the diagnosis of malignant melanomas of the choroid and ciliary body. The 1972 Arthur J. Bedell Lecture. Am J Ophthalmol. 1973, 75: 917-929.CrossRefPubMed
9.
go back to reference Volcker HE, Naumann GO: [Clinically unsuspected malignant melanomas of the posterior uvea (author's transl)]. Klin Monatsbl Augenheilkd. 1976, 168: 311-317.PubMed Volcker HE, Naumann GO: [Clinically unsuspected malignant melanomas of the posterior uvea (author's transl)]. Klin Monatsbl Augenheilkd. 1976, 168: 311-317.PubMed
10.
go back to reference Kitzmann AS, Weaver AL, Lohse CM, Buettner H, Salomao DR: Clinicopathologic correlations in 646 consecutive surgical eye specimens, 1990-2000. Am J Clin Pathol. 2003, 119: 594-601. 10.1309/MLRM-QWAF-V6A1-15UA.CrossRefPubMed Kitzmann AS, Weaver AL, Lohse CM, Buettner H, Salomao DR: Clinicopathologic correlations in 646 consecutive surgical eye specimens, 1990-2000. Am J Clin Pathol. 2003, 119: 594-601. 10.1309/MLRM-QWAF-V6A1-15UA.CrossRefPubMed
11.
go back to reference Shields JA, McDonald PR, Leonard BC, Canny CL: The diagnosis of uveal malignant melanomas in eyes with opaque media. Am J Ophthalmol. 1977, 83: 95-105.CrossRefPubMed Shields JA, McDonald PR, Leonard BC, Canny CL: The diagnosis of uveal malignant melanomas in eyes with opaque media. Am J Ophthalmol. 1977, 83: 95-105.CrossRefPubMed
Metadata
Title
Malignancy in the blind painful eye – report of two cases and literature review
Authors
Patrícia Rusa Pereira
Alexandre Nakao Odashiro
João Pessoa Souza Filho
Vinicius S Saraiva
David Gerardo Camoriano
Miguel N Burnier Jr
Publication date
01-12-2006
Publisher
BioMed Central
Published in
Diagnostic Pathology / Issue 1/2006
Electronic ISSN: 1746-1596
DOI
https://doi.org/10.1186/1746-1596-1-45

Other articles of this Issue 1/2006

Diagnostic Pathology 1/2006 Go to the issue