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Published in: Journal of Occupational Medicine and Toxicology 1/2014

Open Access 01-12-2014 | Review

Chemical and biological work-related risks across occupations in Europe: a review

Author: Diego Montano

Published in: Journal of Occupational Medicine and Toxicology | Issue 1/2014

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Abstract

Background

Work-related health inequalities are determined to some extent by an unequal exposure to chemical and biological risk factors of disease. Although their potential economic burden in the European Union (EU-25) might be substantial, comprehensive reviews focusing on the distribution of these risks across occupational groups are limited. Thus, the main objective of this review is to provide a synopsis of the exposure to chemical and biological hazards across occupational groups. In addition, main industrial applications of hazardous substances are identified and some epidemiological evidence is discussed regarding societal costs and incidence rates of work-related diseases.

Methods

Available lists of carcinogens, sensitisers, mutagens, reprotoxic substances and biological hazards were consulted. For each work-related hazard the main industrial application was identified in order to assess which ISCO occupational groups may be associated with direct exposure. Where available, information on annual tonnage production, risk assessment of the substances and pathogens, and other relevant data were collected and reported.

Results

Altogether 308 chemical and biological hazards were identified which may account to at least 693 direct exposures. These hazards concentrate on the following major occupational groups: technicians (ISCO 3), operators (ISCO 8), agricultural workers (ISCO 6) and workers in elementary occupations (ISCO 9). Common industrial applications associated with increased exposure rates relate among others to: (1) production or application of pigments, resins, cutting fluids, adhesives, pesticides and cleaning products, (2) production of rubber, plastics, textiles, pharmaceuticals and cosmetics, and (3) in agriculture, metallurgy and food processing industry, Societal costs of the unequal distribution of chemical and biological hazards across occupations depend on the corresponding work-related diseases and may range from 2900 EUR to 126000 EUR per case/year.

Conclusions

Risk of exposure to chemical and biological risks and work-related disease incidence are highly concentrated on four occupational groups. The unequal burden of exposure across occupations is an important contributing factor leading to health inequalities in society. The bulk of societal costs, however, are actually being borne by the workers themselves. There is an urgent need of taking into account the health impact of production processes and services on workers’ health.
Appendix
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Literature
1.
go back to reference EU-OSHA: Exploratory Survey Of Occupational Exposure Limits (OELs) for Carcinogens, Mutagens and Reprotoxic substances (CMRs) at EU Member States Level. Luxembourg; 2009. [https://osha.europa.eu] EU-OSHA: Exploratory Survey Of Occupational Exposure Limits (OELs) for Carcinogens, Mutagens and Reprotoxic substances (CMRs) at EU Member States Level. Luxembourg; 2009. [https://​osha.​europa.​eu]
4.
go back to reference Kogevinas M (Ed): Social Inequalities and Cancer, Volume 138. Lyon: IARC scientific publications; 1997. Kogevinas M (Ed): Social Inequalities and Cancer, Volume 138. Lyon: IARC scientific publications; 1997.
5.
go back to reference Logan W: Cancer Mortality by Occupation and Social Class, 1851–1971. No. 36. London: Her Maj. Stat. Office: IARC scientific publications; 1982. Logan W: Cancer Mortality by Occupation and Social Class, 1851–1971. No. 36. London: Her Maj. Stat. Office: IARC scientific publications; 1982.
8.
go back to reference Siemiatycki J, Richardson L, Straif K, Latreille B, Lakhani R, Campbell S, Rousseau MC, Boffetta P: Listing occupational carcinogens. Environ Health Persp 2004,112(15):1447–1459.CrossRef Siemiatycki J, Richardson L, Straif K, Latreille B, Lakhani R, Campbell S, Rousseau MC, Boffetta P: Listing occupational carcinogens. Environ Health Persp 2004,112(15):1447–1459.CrossRef
9.
go back to reference Bödeker W, Barthelmes I: Arbeitsbedingte Gesundheitsgefahren und Berufe mit hoher Krankheitslast in Deutschland. iga-Report 22, Initiative Gesundheit und Arbeit (IGA) 2011, [http://www.iga-info.de] Bödeker W, Barthelmes I: Arbeitsbedingte Gesundheitsgefahren und Berufe mit hoher Krankheitslast in Deutschland. iga-Report 22, Initiative Gesundheit und Arbeit (IGA) 2011, [http://​www.​iga-info.​de]
10.
go back to reference IARC: A Review of Human Carcinogens: Chemical Agents and Related Occupations. Volume 100F. Lyon: IARC; 2012. IARC: A Review of Human Carcinogens: Chemical Agents and Related Occupations. Volume 100F. Lyon: IARC; 2012.
11.
go back to reference IARC: A Review of Human Carcinogens: Radiation. Volume 100D. Lyon: IARC; 2012. IARC: A Review of Human Carcinogens: Radiation. Volume 100D. Lyon: IARC; 2012.
12.
go back to reference IARC: A Review of Human Carcinogens: Arsenic, Metals, Fibres, and Dusts. Volume 100C. Lyon: IARC; 2012. IARC: A Review of Human Carcinogens: Arsenic, Metals, Fibres, and Dusts. Volume 100C. Lyon: IARC; 2012.
13.
go back to reference Kauppinen T, Toikkanen J, Pedersen D, Young R, Ahrens W, Boffetta P, Hansen J, Kromhout H, Blasco JM, Mirabelli D, La Orden-Rivera Vd, Pannett B, Plato N, Savela A, Vincent R, Kogevinas M: Occupational exposure to carcinogens in the European Union. Occup Environ Med 2000, 57: 10–18.PubMedCentralCrossRefPubMed Kauppinen T, Toikkanen J, Pedersen D, Young R, Ahrens W, Boffetta P, Hansen J, Kromhout H, Blasco JM, Mirabelli D, La Orden-Rivera Vd, Pannett B, Plato N, Savela A, Vincent R, Kogevinas M: Occupational exposure to carcinogens in the European Union. Occup Environ Med 2000, 57: 10–18.PubMedCentralCrossRefPubMed
14.
15.
go back to reference Deutsche Forschungsgemeinschaft (DFG): List of MAK and BAT Values 2013: Maximum Concentrations and Biological Tolerance Values at the Workplace. Weinheim: Wiley; 2013.CrossRef Deutsche Forschungsgemeinschaft (DFG): List of MAK and BAT Values 2013: Maximum Concentrations and Biological Tolerance Values at the Workplace. Weinheim: Wiley; 2013.CrossRef
16.
go back to reference Schnuch A, Lessmann H, Schulz KH, Becker D, Diepgen T, Drexler H, Erdmann S, Fartasch M, Greim H, Kricke-Helling P, Merget R, Merk H, Nowak D, Rothe A, Stropp G, Uter W, Wallenstein G: When should a substance be designated as sensitizing for the skin (‘Sh’) or for the airways (‘Sa’)? Hum Exp Toxicol 2002,21(8):439–444.CrossRefPubMed Schnuch A, Lessmann H, Schulz KH, Becker D, Diepgen T, Drexler H, Erdmann S, Fartasch M, Greim H, Kricke-Helling P, Merget R, Merk H, Nowak D, Rothe A, Stropp G, Uter W, Wallenstein G: When should a substance be designated as sensitizing for the skin (‘Sh’) or for the airways (‘Sa’)? Hum Exp Toxicol 2002,21(8):439–444.CrossRefPubMed
17.
go back to reference Akan G, Lemanske R: Allergic disease. Pathophysiology and immunopathology. In Allergic diseases. Edited by: Lieberman P, Anderson J. Humana Press; 2007:1–14.CrossRef Akan G, Lemanske R: Allergic disease. Pathophysiology and immunopathology. In Allergic diseases. Edited by: Lieberman P, Anderson J. Humana Press; 2007:1–14.CrossRef
18.
go back to reference Belsito DV: Occupational contact dermatitis: etiology, prevalence, and resultant impairment/disability. J Am Acad Dermatol 2005,53(2):303–313.CrossRefPubMed Belsito DV: Occupational contact dermatitis: etiology, prevalence, and resultant impairment/disability. J Am Acad Dermatol 2005,53(2):303–313.CrossRefPubMed
19.
go back to reference Raison-Peyron N: Occupational dermatitis diagnosis. Rev Fr Allergol 2006,46, Supplement 1(0):S45-S50. Raison-Peyron N: Occupational dermatitis diagnosis. Rev Fr Allergol 2006,46, Supplement 1(0):S45-S50.
21.
go back to reference Bundesanstalt für ArbeitsschutzundArbeitsmedizin: Technische Regeln für Gefahrstoffe TRGS 905. 2008. Bundesanstalt für ArbeitsschutzundArbeitsmedizin: Technische Regeln für Gefahrstoffe TRGS 905. 2008.
22.
go back to reference Haagsma JA, Tariq L, Heederik DJ, Havelaar AH: Infectious disease risks associated with occupational exposure: a systematic review of the literature. Occup Environ Med 2012,69(2):140–146.CrossRefPubMed Haagsma JA, Tariq L, Heederik DJ, Havelaar AH: Infectious disease risks associated with occupational exposure: a systematic review of the literature. Occup Environ Med 2012,69(2):140–146.CrossRefPubMed
24.
go back to reference Dutkiewicz J, Cisak E, Sroka J, Wojcik-Fatla A, Zajac V: Biological agents as occupational hazards - selected issues. Ann Agr Env Med 2011,18(2):286–293. Dutkiewicz J, Cisak E, Sroka J, Wojcik-Fatla A, Zajac V: Biological agents as occupational hazards - selected issues. Ann Agr Env Med 2011,18(2):286–293.
26.
go back to reference Elvers B (Ed): Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH; 2000. Elvers B (Ed): Ullmann’s Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH; 2000.
31.
go back to reference Pukkala E, Martinsen JI, Lynge E, Gunnarsdottir HK, Sparen P, Tryggvadottir L, Weiderpass E, Kjaerheim K: Occupation and cancer - follow-up of 15 million people in five Nordic countries. Acta oncologica (Stockholm, Sweden) 2009,48(5):646–790.CrossRef Pukkala E, Martinsen JI, Lynge E, Gunnarsdottir HK, Sparen P, Tryggvadottir L, Weiderpass E, Kjaerheim K: Occupation and cancer - follow-up of 15 million people in five Nordic countries. Acta oncologica (Stockholm, Sweden) 2009,48(5):646–790.CrossRef
32.
go back to reference Kogevinas M, Mannetje At, Cordier S, Ranft U, Gonzalez CA, Vineis P, Chang-Claude J, Lynge E, Wahrendorf J, Tzonou A, Jockel KH, Serra C, Porru S, Hours M, Greiser E, Boffetta P: Occupation and bladder cancer among men in Western Europe. Cancer Cause Control 2003,14(10):907–914.CrossRef Kogevinas M, Mannetje At, Cordier S, Ranft U, Gonzalez CA, Vineis P, Chang-Claude J, Lynge E, Wahrendorf J, Tzonou A, Jockel KH, Serra C, Porru S, Hours M, Greiser E, Boffetta P: Occupation and bladder cancer among men in Western Europe. Cancer Cause Control 2003,14(10):907–914.CrossRef
33.
go back to reference Calvert GM, Ward E, Schnorr TM, Fine LJ: Cancer risks among workers exposed to metalworking fluids: a systematic review. Am J Ind Med 1998,33(3):282–292.CrossRefPubMed Calvert GM, Ward E, Schnorr TM, Fine LJ: Cancer risks among workers exposed to metalworking fluids: a systematic review. Am J Ind Med 1998,33(3):282–292.CrossRefPubMed
35.
go back to reference Garcia-Garcia AM, Gadea Merino R, Lopez Martinez V: Estimate of the mortality rate attributable to occupational diseases in Spain, 2004. Rev Esp Salud Public 2007,81(3):261–270. Garcia-Garcia AM, Gadea Merino R, Lopez Martinez V: Estimate of the mortality rate attributable to occupational diseases in Spain, 2004. Rev Esp Salud Public 2007,81(3):261–270.
36.
go back to reference Diepgen TL, Kanerva L: Occupational skin diseases. Eur J Dermatol 2006,16(3):324–330.PubMed Diepgen TL, Kanerva L: Occupational skin diseases. Eur J Dermatol 2006,16(3):324–330.PubMed
37.
go back to reference Rycroft R, Frosch P: Occupational contact dermatitis. In Contact Dermatitis, 4 edition. Edited by: Frosch P, Menne T, Lepoittevin JP. Berlin: Springer; 2006:717–734.CrossRef Rycroft R, Frosch P: Occupational contact dermatitis. In Contact Dermatitis, 4 edition. Edited by: Frosch P, Menne T, Lepoittevin JP. Berlin: Springer; 2006:717–734.CrossRef
39.
go back to reference Halioua B, Bensefa-Colas L, Bouquiaux B, Crepy MN, Assier H, Billon S, Chosidow O: Occupational contact dermatitis in 10,582 French patients reported between 2004 and 2007: a descriptive study. Dermatology 2012,225(4):354–363.CrossRefPubMed Halioua B, Bensefa-Colas L, Bouquiaux B, Crepy MN, Assier H, Billon S, Chosidow O: Occupational contact dermatitis in 10,582 French patients reported between 2004 and 2007: a descriptive study. Dermatology 2012,225(4):354–363.CrossRefPubMed
40.
go back to reference Garcia AM, Gadea R: Incidence and prevalence of occupational diseases in Spain. Aten Prim 2008,40(9):439–445.CrossRef Garcia AM, Gadea R: Incidence and prevalence of occupational diseases in Spain. Aten Prim 2008,40(9):439–445.CrossRef
41.
go back to reference Meyer JD, Chen Y, Holt DL, Beck MH, Cherry NM: Occupational contact dermatitis in the UK: a surveillance report from EPIDERM and OPRA. Occup Med (Lond) 2000,50(4):265–273.CrossRef Meyer JD, Chen Y, Holt DL, Beck MH, Cherry NM: Occupational contact dermatitis in the UK: a surveillance report from EPIDERM and OPRA. Occup Med (Lond) 2000,50(4):265–273.CrossRef
43.
go back to reference Diepgen TL, Scheidt R, Weisshaar E, John SM, Hieke K: Cost of illness from occupational hand eczema in Germany. Contact Dermat 2013,69(2):99–106.CrossRef Diepgen TL, Scheidt R, Weisshaar E, John SM, Hieke K: Cost of illness from occupational hand eczema in Germany. Contact Dermat 2013,69(2):99–106.CrossRef
44.
go back to reference Cortesi PA, Scalone L, Belisari A, Bonamonte D, Cannavo SP, Cristaudo A, Pita Od, Gallo R, Giannetti A, Gola M, Pigatto PD, Mantovani LG: Cost and quality of life in patients with severe chronic hand eczema refractory to standard therapy with topical potent corticosteroids. Contact Dermat 2013,70(3):158–168.CrossRef Cortesi PA, Scalone L, Belisari A, Bonamonte D, Cannavo SP, Cristaudo A, Pita Od, Gallo R, Giannetti A, Gola M, Pigatto PD, Mantovani LG: Cost and quality of life in patients with severe chronic hand eczema refractory to standard therapy with topical potent corticosteroids. Contact Dermat 2013,70(3):158–168.CrossRef
45.
go back to reference Sajjachareonpong P, Cahill J, Keegel T, Saunders H, Nixon R: Persistent post-occupational dermatitis. Contact Dermat 2004,51(5–6):278–283.CrossRef Sajjachareonpong P, Cahill J, Keegel T, Saunders H, Nixon R: Persistent post-occupational dermatitis. Contact Dermat 2004,51(5–6):278–283.CrossRef
50.
go back to reference Kogevinas M, Zock JP, Jarvis D, Kromhout H, Lillienberg L, Plana E, Radon K, Torén K, Alliksoo A, Benke G, Blanc PD, Dahlman-Hoglund A, D’Errico A, Héry M, Kennedy S, Kunzli N, Leynaert B, Mirabelli MC, Muniozguren N, Norbäck D, Olivieri M, Payo F, Villani S, van Sprundel M, Urrutia I, Wieslander G, Sunyer J, Antó JM: Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II). Lancet 2007,370(9584):336–341.CrossRefPubMed Kogevinas M, Zock JP, Jarvis D, Kromhout H, Lillienberg L, Plana E, Radon K, Torén K, Alliksoo A, Benke G, Blanc PD, Dahlman-Hoglund A, D’Errico A, Héry M, Kennedy S, Kunzli N, Leynaert B, Mirabelli MC, Muniozguren N, Norbäck D, Olivieri M, Payo F, Villani S, van Sprundel M, Urrutia I, Wieslander G, Sunyer J, Antó JM: Exposure to substances in the workplace and new-onset asthma: an international prospective population-based study (ECRHS-II). Lancet 2007,370(9584):336–341.CrossRefPubMed
51.
go back to reference Burge S, Hoyle J: Current topics in occupational asthma. Expert Rev Respir Med 2012,6(6):615–627.CrossRefPubMed Burge S, Hoyle J: Current topics in occupational asthma. Expert Rev Respir Med 2012,6(6):615–627.CrossRefPubMed
52.
go back to reference Baur X, Degens P, Weber K: Occupational obstructive airway diseases in Germany. Am J Ind Med 1998,33(5):454–462.CrossRefPubMed Baur X, Degens P, Weber K: Occupational obstructive airway diseases in Germany. Am J Ind Med 1998,33(5):454–462.CrossRefPubMed
53.
go back to reference Vandenplas O, Labarnois A, Bugli C, Kempeneers E, Nemery B: Epidemiologie de l’asthme professionnel en Belgique. Rev Mal Respi 2005, 22: 421–430.CrossRef Vandenplas O, Labarnois A, Bugli C, Kempeneers E, Nemery B: Epidemiologie de l’asthme professionnel en Belgique. Rev Mal Respi 2005, 22: 421–430.CrossRef
54.
go back to reference Ameille J, Pauli G, Calastreng-Crinquand A, Vervloet D, Iwatsubo Y, Popin E, Bayeux-Dunglas MC, Kopferschmitt-Kubler MC: Reported incidence of occupational asthma in France, 1996–99: the ONAP programme. Occup Environ Med 2003,60(2):136–141.PubMedCentralCrossRefPubMed Ameille J, Pauli G, Calastreng-Crinquand A, Vervloet D, Iwatsubo Y, Popin E, Bayeux-Dunglas MC, Kopferschmitt-Kubler MC: Reported incidence of occupational asthma in France, 1996–99: the ONAP programme. Occup Environ Med 2003,60(2):136–141.PubMedCentralCrossRefPubMed
55.
go back to reference McDonald JC, Keynes HL, Meredith SK: Reported incidence of occupational asthma in the United Kingdom, 1989–97. Occup Environ Med 2000,57(12):823–829.PubMedCentralCrossRefPubMed McDonald JC, Keynes HL, Meredith SK: Reported incidence of occupational asthma in the United Kingdom, 1989–97. Occup Environ Med 2000,57(12):823–829.PubMedCentralCrossRefPubMed
56.
go back to reference Karjalainen A, Kurppa K, Virtanen S, Keskinen H, Nordman H: Incidence of occupational asthma by occupation and industry in Finland. Am J Ind Med 2000,37(5):451–458.CrossRefPubMed Karjalainen A, Kurppa K, Virtanen S, Keskinen H, Nordman H: Incidence of occupational asthma by occupation and industry in Finland. Am J Ind Med 2000,37(5):451–458.CrossRefPubMed
57.
go back to reference Dykewicz MS: Occupational asthma: current concepts in pathogenesis, diagnosis, and management. J Allergy Clin Immun 2009,123(3):519–528; quiz 529–530.CrossRefPubMed Dykewicz MS: Occupational asthma: current concepts in pathogenesis, diagnosis, and management. J Allergy Clin Immun 2009,123(3):519–528; quiz 529–530.CrossRefPubMed
58.
go back to reference Malo JL, Chan-Yeung M: Agents causing occupational asthma. J Allergy Clin Immun 2009,123(3):545–550.CrossRefPubMed Malo JL, Chan-Yeung M: Agents causing occupational asthma. J Allergy Clin Immun 2009,123(3):545–550.CrossRefPubMed
60.
go back to reference Siracusa A, Blay Fd, Folletti I, Moscato G, Olivieri M, Quirce S, Raulf-Heimsoth M, Sastre J, Tarlo SM, Walusiak-Skorupa J, Zock JP: Asthma and exposure to cleaning products - a European Academy of Allergy and Clinical Immunology task force consensus statement. Allergy 2013,68(12):1532–1545.CrossRefPubMed Siracusa A, Blay Fd, Folletti I, Moscato G, Olivieri M, Quirce S, Raulf-Heimsoth M, Sastre J, Tarlo SM, Walusiak-Skorupa J, Zock JP: Asthma and exposure to cleaning products - a European Academy of Allergy and Clinical Immunology task force consensus statement. Allergy 2013,68(12):1532–1545.CrossRefPubMed
62.
go back to reference Jacobsen G, Schaumburg I, Sigsgaard T, Schlunssen V: Non-malignant respiratory diseases and occupational exposure to wood dust. Part I. Fresh wood and mixed wood industry. Ann Agr Env Med 2010, 17: 15–28. Jacobsen G, Schaumburg I, Sigsgaard T, Schlunssen V: Non-malignant respiratory diseases and occupational exposure to wood dust. Part I. Fresh wood and mixed wood industry. Ann Agr Env Med 2010, 17: 15–28.
63.
go back to reference Moscato G, Vandenplas O, Van Wijk RG, Malo JL, Perfetti L, Quirce S, Walusiak J, Castano R, Pala G, Gautrin D, De Groot H, Folletti I, Yacoub MR, Siracusa A, European Academy of Allergology and Clinical Immunolgy: EAACI position paper on occupational rhinitis. Respir Res 2009, 10: 16.PubMedCentralCrossRefPubMed Moscato G, Vandenplas O, Van Wijk RG, Malo JL, Perfetti L, Quirce S, Walusiak J, Castano R, Pala G, Gautrin D, De Groot H, Folletti I, Yacoub MR, Siracusa A, European Academy of Allergology and Clinical Immunolgy: EAACI position paper on occupational rhinitis. Respir Res 2009, 10: 16.PubMedCentralCrossRefPubMed
64.
go back to reference Ameille J, Hamelin K, Andujar P, Bensefa-Colas L, Bonneterre V, Dupas D, Garnier R, Lodde BA, Rinaldo M, Descatha A, Lasfargues G, Pairon JC: Occupational asthma and occupational rhinitis: the united airways disease model revisited. Occup Environ Med 2013,70(7):471–475.PubMedCentralCrossRefPubMed Ameille J, Hamelin K, Andujar P, Bensefa-Colas L, Bonneterre V, Dupas D, Garnier R, Lodde BA, Rinaldo M, Descatha A, Lasfargues G, Pairon JC: Occupational asthma and occupational rhinitis: the united airways disease model revisited. Occup Environ Med 2013,70(7):471–475.PubMedCentralCrossRefPubMed
65.
go back to reference Hytonen M, Kanerva L, Malmberg H, Martikainen R, Mutanen P, Toikkanen J: The risk of occupational rhinitis. Int Arch Occ Env Health 1997,69(6):487–490.CrossRef Hytonen M, Kanerva L, Malmberg H, Martikainen R, Mutanen P, Toikkanen J: The risk of occupational rhinitis. Int Arch Occ Env Health 1997,69(6):487–490.CrossRef
68.
go back to reference Smith AM, Bernstein DI: Management of work-related asthma. J Allergy Clin Immun 2009,123(3):551–557.CrossRefPubMed Smith AM, Bernstein DI: Management of work-related asthma. J Allergy Clin Immun 2009,123(3):551–557.CrossRefPubMed
70.
go back to reference Ferguson KK, O’Neill MS, Meeker JD: Environmental contaminant exposures and preterm birth: a comprehensive review. J Toxicol Env Health B Crit Rev 2013,16(2):69–113.CrossRef Ferguson KK, O’Neill MS, Meeker JD: Environmental contaminant exposures and preterm birth: a comprehensive review. J Toxicol Env Health B Crit Rev 2013,16(2):69–113.CrossRef
72.
go back to reference Windham G, Fenster L: Environmental contaminants and pregnancy outcomes. Fertil Steril 2008,89(2 SUPPL):e111—e116.PubMed Windham G, Fenster L: Environmental contaminants and pregnancy outcomes. Fertil Steril 2008,89(2 SUPPL):e111—e116.PubMed
73.
go back to reference Singer TM, Yauk CL: Germ cell mutagens: risk assessment challenges in the 21st century. Environ Mol Mutagen 2010,51(8–9):919–928.CrossRefPubMed Singer TM, Yauk CL: Germ cell mutagens: risk assessment challenges in the 21st century. Environ Mol Mutagen 2010,51(8–9):919–928.CrossRefPubMed
75.
go back to reference Winker R, Rudiger HW: Reproductive toxicology in occupational settings: an update. Int Arch Occ Env Health 2006, 79: 1–10.CrossRef Winker R, Rudiger HW: Reproductive toxicology in occupational settings: an update. Int Arch Occ Env Health 2006, 79: 1–10.CrossRef
76.
go back to reference Baranski B: Effects of the workplace on fertility and related reproductive outcomes. Environ Health Persp 1993, 101 Suppl 2: 81–90.CrossRef Baranski B: Effects of the workplace on fertility and related reproductive outcomes. Environ Health Persp 1993, 101 Suppl 2: 81–90.CrossRef
77.
go back to reference Snijder CA, te Velde E, Roeleveld N, Burdorf A: Occupational exposure to chemical substances and time to pregnancy: a systematic review. Hum Reprod Update 2012,18(3):284–300.CrossRefPubMed Snijder CA, te Velde E, Roeleveld N, Burdorf A: Occupational exposure to chemical substances and time to pregnancy: a systematic review. Hum Reprod Update 2012,18(3):284–300.CrossRefPubMed
78.
go back to reference Wigle DT, Turner MC, Krewski D: A systematic review and meta-analysis of childhood leukemia and parental occupational pesticide exposure. Environ Health Persp 2009,117(10):1505–1513.CrossRef Wigle DT, Turner MC, Krewski D: A systematic review and meta-analysis of childhood leukemia and parental occupational pesticide exposure. Environ Health Persp 2009,117(10):1505–1513.CrossRef
79.
go back to reference Vinson F, Merhi M, Baldi I, Raynal H, Gamet-Payrastre L: Exposure to pesticides and risk of childhood cancer: a meta-analysis of recent epidemiological studies. Occup Environ Med 2011,68(9):694–702.CrossRefPubMed Vinson F, Merhi M, Baldi I, Raynal H, Gamet-Payrastre L: Exposure to pesticides and risk of childhood cancer: a meta-analysis of recent epidemiological studies. Occup Environ Med 2011,68(9):694–702.CrossRefPubMed
80.
go back to reference Góra A, Mackiewicz B, Krawczyk P, Golec M, Skórska C, Sitkowska J, Cholewa G, Larsson L, Jarosz M, Wójcik-Fatla A, Dutkiewicz J: Occupational exposure to organic dust, microorganisms, endotoxin and peptidoglycan among plants processing workers in Poland. Ann Agr Env Med 2009, 16: 143–150. Góra A, Mackiewicz B, Krawczyk P, Golec M, Skórska C, Sitkowska J, Cholewa G, Larsson L, Jarosz M, Wójcik-Fatla A, Dutkiewicz J: Occupational exposure to organic dust, microorganisms, endotoxin and peptidoglycan among plants processing workers in Poland. Ann Agr Env Med 2009, 16: 143–150.
81.
go back to reference Bundesanstalt für Arbeitsschutz und Arbeitsmedizin: Criteria for the classification of biological agents TRBA 450. 2004. Bundesanstalt für Arbeitsschutz und Arbeitsmedizin: Criteria for the classification of biological agents TRBA 450. 2004.
82.
go back to reference Menzies D, Joshi R, Pai M: Risk of tuberculosis infection and disease associated with work in health care settings. Int J Tuberc Lung Dis 2007,11(6):593–605.PubMed Menzies D, Joshi R, Pai M: Risk of tuberculosis infection and disease associated with work in health care settings. Int J Tuberc Lung Dis 2007,11(6):593–605.PubMed
83.
go back to reference FitzSimons D, Francois Gk, De Carli G, Shouval D, Prüss-Ustün A, Puro V, Williams I, Lavanchy D, De Schryver A, Kopka A, Ncube F, Ippolito G, Van Damme P: Hepatitis B virus, hepatitis C virus and other blood-borne infections in healthcare workers: Guidelines for prevention and management in industrialised countries. Occup Environ Med 2008,65(7):446–451.CrossRefPubMed FitzSimons D, Francois Gk, De Carli G, Shouval D, Prüss-Ustün A, Puro V, Williams I, Lavanchy D, De Schryver A, Kopka A, Ncube F, Ippolito G, Van Damme P: Hepatitis B virus, hepatitis C virus and other blood-borne infections in healthcare workers: Guidelines for prevention and management in industrialised countries. Occup Environ Med 2008,65(7):446–451.CrossRefPubMed
84.
go back to reference Rapiti E, Prüss-Üstün A, Hutin Y: Sharps injuries: assessing the burden of disease from sharps injuries to health-care workers at national and local levels. Geneva 2005, [http://www.who.int] Rapiti E, Prüss-Üstün A, Hutin Y: Sharps injuries: assessing the burden of disease from sharps injuries to health-care workers at national and local levels. Geneva 2005, [http://​www.​who.​int]
86.
87.
go back to reference Zukiewicz-Sobczak WA, Chmielewska-Badora J, Wróblewska P, Zwoliński J: Farmers’ occupational diseases of allergenic and zoonotic origin. Postep Derm Alergol 2013,30(5):311–315.CrossRef Zukiewicz-Sobczak WA, Chmielewska-Badora J, Wróblewska P, Zwoliński J: Farmers’ occupational diseases of allergenic and zoonotic origin. Postep Derm Alergol 2013,30(5):311–315.CrossRef
88.
go back to reference Déléry L, Cicolella A: Occupational and environmental endotoxin exposure from agricultural and industrial workplaces, a literature review. Environ Risque Sante 2009, 8: 35–45. Déléry L, Cicolella A: Occupational and environmental endotoxin exposure from agricultural and industrial workplaces, a literature review. Environ Risque Sante 2009, 8: 35–45.
89.
go back to reference Samadi S, Wouters IM, Heederik DJJ: A review of bio-aerosol exposures and associated health effects in veterinary practice. Ann Agr Env Med 2013,20(2):206–221. Samadi S, Wouters IM, Heederik DJJ: A review of bio-aerosol exposures and associated health effects in veterinary practice. Ann Agr Env Med 2013,20(2):206–221.
90.
go back to reference Basinas I, Schlünssen V, Heederik D, Sigsgaard T, Smit LAM, Samadi S, Omland Ø, Hjort C, Madsen AM, Skov S, Wouters IM: Sensitisation to common allergens and respiratory symptoms in endotoxin exposed workers: a pooled analysis. Occup Environ Med 2012,69(2):99–106.CrossRefPubMed Basinas I, Schlünssen V, Heederik D, Sigsgaard T, Smit LAM, Samadi S, Omland Ø, Hjort C, Madsen AM, Skov S, Wouters IM: Sensitisation to common allergens and respiratory symptoms in endotoxin exposed workers: a pooled analysis. Occup Environ Med 2012,69(2):99–106.CrossRefPubMed
91.
go back to reference Basinas I, Sigsgaard T, Heederik D, Takai H, Omland O, Andersen NT, Wouters IM, Bønløkke JH, Kromhout H, Schlünssen V: Exposure to inhalable dust and endotoxin among Danish livestock farmers: Results from the SUS cohort study. J Environ Monitor 2012,14(2):604–614.CrossRef Basinas I, Sigsgaard T, Heederik D, Takai H, Omland O, Andersen NT, Wouters IM, Bønløkke JH, Kromhout H, Schlünssen V: Exposure to inhalable dust and endotoxin among Danish livestock farmers: Results from the SUS cohort study. J Environ Monitor 2012,14(2):604–614.CrossRef
92.
go back to reference Tabibi R, Baccalini R, Barassi A, Bonizzi L, Brambilla G, Consonni D, Melzi d’Eril G, Romano L, Sokooti M, Somaruga C, Vellere F, Zanetti A, Colosio C: Occupational exposure to zoonotic agents among agricultural workers in Lombardy Region, northern Italy. Ann Agr Env Med 2013,20(4):676–681. Tabibi R, Baccalini R, Barassi A, Bonizzi L, Brambilla G, Consonni D, Melzi d’Eril G, Romano L, Sokooti M, Somaruga C, Vellere F, Zanetti A, Colosio C: Occupational exposure to zoonotic agents among agricultural workers in Lombardy Region, northern Italy. Ann Agr Env Med 2013,20(4):676–681.
93.
go back to reference Garcia-Alvarez L, Dawson S, Cookson B, Hawkey P: Working across the veterinary and human health sectors. J Antimicrob Chemoth 2012,67(SUPPL.1):i37—i49. Garcia-Alvarez L, Dawson S, Cookson B, Hawkey P: Working across the veterinary and human health sectors. J Antimicrob Chemoth 2012,67(SUPPL.1):i37—i49.
95.
go back to reference van Vliet E: Current standing and future prospects for the technologies proposed to transform toxicity testing in the 21st century. ALTEX 2011, 28: 17–44.CrossRefPubMed van Vliet E: Current standing and future prospects for the technologies proposed to transform toxicity testing in the 21st century. ALTEX 2011, 28: 17–44.CrossRefPubMed
Metadata
Title
Chemical and biological work-related risks across occupations in Europe: a review
Author
Diego Montano
Publication date
01-12-2014
Publisher
BioMed Central
Published in
Journal of Occupational Medicine and Toxicology / Issue 1/2014
Electronic ISSN: 1745-6673
DOI
https://doi.org/10.1186/1745-6673-9-28

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