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Published in: Trials 1/2007

Open Access 01-12-2007 | Commentary

Standardising outcomes for clinical trials and systematic reviews

Author: Mike Clarke

Published in: Trials | Issue 1/2007

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Excerpt

Fifteen years ago, what was to become OMERACT met for the first time in The Netherlands to discuss ways in which the multitude of outcomes in assessments of the effects of treatments for rheumatoid arthritis might be standardised. In Trials, Tugwell et al have described the need for, and success of, this initiative [1] and Cooney and colleagues have set out their plans for a corresponding initiative for ulcerative colitis [2]. Why do we need such initiatives? What's the problem? And are these and other initiatives the solution? …
Literature
1.
Tugwell P, Boers M, Brooks P, Simon LS, Strand V: OMERACT: An international initiative to improve outcome measurement in rheumatology. Trials. 2007
2.
Cooney RM, Warren BF, Altman DG, Abreu MT, Travis SPL: Outcome measurement in clinical trials for ulcerative colitis: toward standardisation. Trials. 2007, 8: 17-10.1186/1745-6215-8-17.CrossRefPubMedPubMedCentral
3.
Williamson PR, Gamble C, Altman DG, Hutton JL: Outcome selection bias in meta-analysis. Statistical Methods in Medical Research. 2005, 14: 515-524. 10.1191/0962280205sm415oa.CrossRefPubMed
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Marshall M, Lockwood A, Bradley C, Adams C, Joy C, Fenton M: Unpublished rating scales: a major source of bias in randomized controlled trials of treatments for schizophrenia. British Journal of Psychiatry. 2000, 176: 249-252. 10.1192/bjp.176.3.249.CrossRefPubMed
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Adams CE, Awad G, Rathbone J, Thornley B: Chlorpromazine versus placebo for schizophrenia. Cochrane Database of Systematic Reviews. 2007, 18 (2): CD000284-
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World Health Organisation: WHO Handbook for Reporting Results of Cancer Treatment. WHO Offset publication No 48. 1979, Geneva: WHO
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Miller AB, Hoogstraten B, Staquet M, Winkler A: Reporting results of cancer treatment. Cancer. 1981, 47: 207-214. 10.1002/1097-0142(19810101)47:1<207::AID-CNCR2820470134>3.0.CO;2-6.CrossRefPubMed
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Dworkin RH, Turk DC, Farrar JT, Haythornthwaite JA, Jensen MP, Katz NP, Kerns RD, Stucki G, Allen RR, Bellamy N, Carr DB, Chandler J, Cowan P, Dionne R, Galer BS, Hertz S, Jadad AR, Kramer LD, Manning DC, Martin S, McCormick CG, McDermott MP, McGrath P, Quessy S, Rappaport BA, Robbins W, Robinson JP, Rothman M, Royal MA, Simon L: Core outcome measures for chronic pain trials: IMMPACT recommendations. Pain. 2005, 113: 9-19. 10.1016/j.pain.2004.09.012.CrossRefPubMed
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de Vet HCW, Heymans MW, Dunn KM, Pope DP, van der Beek AJ, Macfarlane GJ, Bouter LM, Croft PR: Episodes of low back pain: A proposal for uniform definitions to be used in research. Spine. 2002, 27: 2409-2416. 10.1097/00007632-200211010-00016.CrossRefPubMed
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Punt CJA, Buyse M, Köhne CH, Hohenberger P, Labianca R, Schmoll HJ, Påhlman L, Sobrero A, Douillard JY: Endpoints in adjuvant treatment trials: a systematic review of the literature in colon cancer and proposed definitions for future trials. Journal of the National Cancer Institute. 2007, 99: 998-1003. 10.1093/jnci/djm024.CrossRefPubMed
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Devane D, Begley CM, Clarke M, Horey D, O'Boyle C: Evaluating maternity care: a core set of outcome measures. Birth. 2007, 34 (2): 164-172. 10.1111/j.1523-536X.2006.00145.x.CrossRefPubMed
Metadata
Title
Standardising outcomes for clinical trials and systematic reviews
Author
Mike Clarke
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Trials / Issue 1/2007
Electronic ISSN: 1745-6215
DOI
https://doi.org/10.1186/1745-6215-8-39

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