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Published in: Globalization and Health 1/2013

Open Access 01-12-2013 | Research

Screening for diabetes and hypertension in a rural low income setting in western Kenya utilizing home-based and community-based strategies

Authors: Sonak D Pastakia, Shamim M Ali, Jemima H Kamano, Constantine O Akwanalo, Samson K Ndege, Victor L Buckwalter, Rajesh Vedanthan, Gerald S Bloomfield

Published in: Globalization and Health | Issue 1/2013

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Abstract

Background

The burdens of hypertension and diabetes are increasing in low- and middle-income countries (LMICs). It is important to identify patients with these conditions early in the disease process. The goal of this study, therefore, is to compare community- versus home-based screening for hypertension and diabetes in Kenya.

Methods

This was a feasibility study conducted by the Academic Model Providing Access to Healthcare (AMPATH) program in Webuye, a town in western Kenya. Home-based (door-to-door) screening occurred in March 2010 and community-based screening in November 2011. HIV counselors were trained to screen for diabetes and hypertension in the home-based screening with local district hospital based staff conducting the community-based screening. Participants >18 years old qualified for screening in both groups. Counselors referred all participants with a systolic blood pressure (SBP) ≥160 mmHg and/or a random blood glucose ≥7 mmol/L (126 mg/dL) to a local clinic for follow-up. Differences in likelihood of screening positive between the two strategies were compared using Fischer’s Exact Test. Logistic regression models were used to identify factors associated with the likelihood of following-up after a positive screening.

Results

There were 236 participants in home-based screening: 13 (6%) had a SBP ≥160 mmHg, and 54 (23%) had a random glucose ≥ 7 mmol/L. There were 346 participants in community-based screening: 35 (10%) had a SBP ≥160 mmHg, and 27 (8%) had a random glucose ≥ 7 mmol/L. Participants in community-based screening were twice as likely to screen positive for hypertension compared to home-based screening (OR=1.93, P=0.06). In contrast, participants were 3.5 times more likely to screen positive for a random blood glucose ≥7 mmol/L with home-based screening (OR=3.51, P<0.01). Rates for following-up at the clinic after a positive screen were low for both groups with 31% of patients with an elevated SBP returning for confirmation in both the community-based and home-based group (P=1.0). Follow-up after a random glucose was also low with 23% returning in the home-based group and 22% in the community-based group (P=1.0).

Conclusion

Community- or home-based screening for diabetes and hypertension in LMICs is feasible. Due to low rates of follow-up, screening efforts in rural settings should focus on linking cases to care.
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Literature
1.
go back to reference World Health Organization: Cardiovascular Diseases in the African Region: Current Situation and Perspectives. 2005, Geneva: Report of the Regional Director World Health Organization: Cardiovascular Diseases in the African Region: Current Situation and Perspectives. 2005, Geneva: Report of the Regional Director
2.
go back to reference Bloomfield GS, Kimaiyo S, Carter EJ, Binanay C, Corey GR, Einterz RM, Tierney WM, Velazquez EJ: Chronic noncommunicable cardiovascular and pulmonary disease in sub-Saharan Africa: An academic model for countering the epidemic. Am Heart J. 2011, 161: 842-847. 10.1016/j.ahj.2010.12.020.PubMedCentralCrossRefPubMed Bloomfield GS, Kimaiyo S, Carter EJ, Binanay C, Corey GR, Einterz RM, Tierney WM, Velazquez EJ: Chronic noncommunicable cardiovascular and pulmonary disease in sub-Saharan Africa: An academic model for countering the epidemic. Am Heart J. 2011, 161: 842-847. 10.1016/j.ahj.2010.12.020.PubMedCentralCrossRefPubMed
3.
go back to reference Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK: The Global burden of hypertension: analysis of worldwide data. Lancet. 2005, 365: 217-223.CrossRefPubMed Kearney PM, Whelton M, Reynolds K, Muntner P, Whelton PK: The Global burden of hypertension: analysis of worldwide data. Lancet. 2005, 365: 217-223.CrossRefPubMed
4.
go back to reference Mufunda J, Chatora R, Ndambakuwa Y, Nyarango P, Kosia A, Chifamba J, Filipe A, Usman A, Sparks VH: Emerging non-communicable disease epidemic in Africa: preventive measures from the WHO Regional Office for Africa. Ethn Dis. 2006, 16: 521-526.PubMed Mufunda J, Chatora R, Ndambakuwa Y, Nyarango P, Kosia A, Chifamba J, Filipe A, Usman A, Sparks VH: Emerging non-communicable disease epidemic in Africa: preventive measures from the WHO Regional Office for Africa. Ethn Dis. 2006, 16: 521-526.PubMed
6.
go back to reference Mbanya JC, Motala AA, Sobngwi , Assah FK, Enoru ST: Diabetes in sub-Saharan Africa. Lancet. 2010, 375: 2254-2266. 10.1016/S0140-6736(10)60550-8.CrossRefPubMed Mbanya JC, Motala AA, Sobngwi , Assah FK, Enoru ST: Diabetes in sub-Saharan Africa. Lancet. 2010, 375: 2254-2266. 10.1016/S0140-6736(10)60550-8.CrossRefPubMed
7.
go back to reference Mathenge W, Foster A, Kuper H: Urbanization, ethnicity and cardiovascular risk in a population in transition in Nakuru, Kenya: a population-based survey. BMC Publ Health. 2010, 10: 569-10.1186/1471-2458-10-569.CrossRef Mathenge W, Foster A, Kuper H: Urbanization, ethnicity and cardiovascular risk in a population in transition in Nakuru, Kenya: a population-based survey. BMC Publ Health. 2010, 10: 569-10.1186/1471-2458-10-569.CrossRef
8.
go back to reference Addo J, Smeeth L, Leon DA: Hypertension in sub-saharan Africa: a systematic review. Hypertension. 2007, 50: 1012-1018. 10.1161/HYPERTENSIONAHA.107.093336.CrossRefPubMed Addo J, Smeeth L, Leon DA: Hypertension in sub-saharan Africa: a systematic review. Hypertension. 2007, 50: 1012-1018. 10.1161/HYPERTENSIONAHA.107.093336.CrossRefPubMed
9.
go back to reference Kimaiyo S, Were MC, Shen C, Ndege S, Braitstein P, Sidle J, Mamlin J: Home-based HIV counseling and testing in western Kenya. East African Med J. 2010, 87: 100-108.CrossRef Kimaiyo S, Were MC, Shen C, Ndege S, Braitstein P, Sidle J, Mamlin J: Home-based HIV counseling and testing in western Kenya. East African Med J. 2010, 87: 100-108.CrossRef
10.
go back to reference Einterz RM, Kimaiyo S, Mengech HN, Khwa-Otsyula BO, Esamai F, Quigley F, Mamlin JJ: Responding to the HIV pandemic: the power of an academic medical partnership. Acad Med. 2007, 82: 812-818. 10.1097/ACM.0b013e3180cc29f1.CrossRefPubMed Einterz RM, Kimaiyo S, Mengech HN, Khwa-Otsyula BO, Esamai F, Quigley F, Mamlin JJ: Responding to the HIV pandemic: the power of an academic medical partnership. Acad Med. 2007, 82: 812-818. 10.1097/ACM.0b013e3180cc29f1.CrossRefPubMed
12.
go back to reference Wachira J, Kimaiyo S, Ndege S, Mamlin J, Braitstein P: What is the impact of home-based HIV counseling and testing on the clinical status of newly enrolled adults in a large HIV care program in western Kenya?. Clin Infect Dis. 2012, 54: 275-281. 10.1093/cid/cir789.CrossRefPubMed Wachira J, Kimaiyo S, Ndege S, Mamlin J, Braitstein P: What is the impact of home-based HIV counseling and testing on the clinical status of newly enrolled adults in a large HIV care program in western Kenya?. Clin Infect Dis. 2012, 54: 275-281. 10.1093/cid/cir789.CrossRefPubMed
13.
go back to reference Pastakia SD, Karwa R, Kahn CB, Nyabundi JS: Evolution of Diabetes Care Through Partnerships in a Rural Resource-Constrained Setting. Ann Pharmacother. 2011, 45: 1-6. 10.1345/aph.1P301.CrossRef Pastakia SD, Karwa R, Kahn CB, Nyabundi JS: Evolution of Diabetes Care Through Partnerships in a Rural Resource-Constrained Setting. Ann Pharmacother. 2011, 45: 1-6. 10.1345/aph.1P301.CrossRef
15.
go back to reference Kario K, Schwartz JE, Pickering TG: Changes of nocturnal blood pressure dipping status in hypertensives by nighttime dosing of alpha-adrenergic blocker, doxazosin: results from the HALT study. Hypertension. 2000, 35: 787-794. 10.1161/01.HYP.35.3.787.CrossRefPubMed Kario K, Schwartz JE, Pickering TG: Changes of nocturnal blood pressure dipping status in hypertensives by nighttime dosing of alpha-adrenergic blocker, doxazosin: results from the HALT study. Hypertension. 2000, 35: 787-794. 10.1161/01.HYP.35.3.787.CrossRefPubMed
16.
go back to reference Opie LH, Seedat YK: Hypertension in sub-Saharan African populations. Circulation. 2005, 112: 3562-3568. 10.1161/CIRCULATIONAHA.105.539569.CrossRefPubMed Opie LH, Seedat YK: Hypertension in sub-Saharan African populations. Circulation. 2005, 112: 3562-3568. 10.1161/CIRCULATIONAHA.105.539569.CrossRefPubMed
17.
go back to reference Bovet P, Gervasoni JP, Mkamba M, Balampama M, Lengeler C, Paccaud F: Low utilization of health care services following screening for hypertension in Dar es Salaam (Tanzania): a prospective population-based study. BMC Publ Health. 2008, 8: 1-8. 10.1186/1471-2458-8-1.CrossRef Bovet P, Gervasoni JP, Mkamba M, Balampama M, Lengeler C, Paccaud F: Low utilization of health care services following screening for hypertension in Dar es Salaam (Tanzania): a prospective population-based study. BMC Publ Health. 2008, 8: 1-8. 10.1186/1471-2458-8-1.CrossRef
18.
go back to reference Seedat YK, Rayner BL: South African Hypertension Guideline 2011. S Afr Med J. 2012, 102: 57-84. Seedat YK, Rayner BL: South African Hypertension Guideline 2011. S Afr Med J. 2012, 102: 57-84.
19.
go back to reference Tin LL, Beevers DG, Lip GY: Systolic vs diastolic blood pressure and the burden of hypertension. J Hum Hypertens. 2002, 16: 147-150. 10.1038/sj.jhh.1001373.CrossRefPubMed Tin LL, Beevers DG, Lip GY: Systolic vs diastolic blood pressure and the burden of hypertension. J Hum Hypertens. 2002, 16: 147-150. 10.1038/sj.jhh.1001373.CrossRefPubMed
21.
go back to reference Steyn K, Sliwa K, Hawken S, Commerford P, Onen C, Damasceno A, Ounpuu S, Yusuf S, INTERHEART Investigators in Africa: Risk factors associated with myocardial infarction in Africa: the INTERHEART Africa study. Circulation. 2005, 112: 3554-3561. 10.1161/CIRCULATIONAHA.105.563452.CrossRefPubMed Steyn K, Sliwa K, Hawken S, Commerford P, Onen C, Damasceno A, Ounpuu S, Yusuf S, INTERHEART Investigators in Africa: Risk factors associated with myocardial infarction in Africa: the INTERHEART Africa study. Circulation. 2005, 112: 3554-3561. 10.1161/CIRCULATIONAHA.105.563452.CrossRefPubMed
22.
go back to reference van den Donk M, Sandbaek A, Borch-Johnsen K, Lauritzen T, Simmons RK, Wareham NJ, Griffin SJ, Davies MJ, Khunti K, Rutten GEHM: Screening for type 2 diabetes. Lessons from the ADDITION-Europe study. Diabet Med. 2011, 28: 1416-1424. 10.1111/j.1464-5491.2011.03365.x.CrossRefPubMed van den Donk M, Sandbaek A, Borch-Johnsen K, Lauritzen T, Simmons RK, Wareham NJ, Griffin SJ, Davies MJ, Khunti K, Rutten GEHM: Screening for type 2 diabetes. Lessons from the ADDITION-Europe study. Diabet Med. 2011, 28: 1416-1424. 10.1111/j.1464-5491.2011.03365.x.CrossRefPubMed
23.
24.
go back to reference Nasir MN, Thevarajah M, Yean YC: Hemoglobin variants detected by hemoglobin A1c analysis and the effects on HbA1c measurements. Int J Diabetes Dev Ctries. 2010, 30: 86-90. 10.4103/0973-3930.62598.PubMedCentralCrossRefPubMed Nasir MN, Thevarajah M, Yean YC: Hemoglobin variants detected by hemoglobin A1c analysis and the effects on HbA1c measurements. Int J Diabetes Dev Ctries. 2010, 30: 86-90. 10.4103/0973-3930.62598.PubMedCentralCrossRefPubMed
25.
go back to reference Kirk JK, D’Agostino RB, Bell RA, Passmore LV, Bonds DE, Karter AJ, Narayan KMV: Disparities in HbA1c levels between African-American and Non-Hispanic white adults with diabetes. Diabetes Care. 2006, 29: 2130-2136. 10.2337/dc05-1973.PubMedCentralCrossRefPubMed Kirk JK, D’Agostino RB, Bell RA, Passmore LV, Bonds DE, Karter AJ, Narayan KMV: Disparities in HbA1c levels between African-American and Non-Hispanic white adults with diabetes. Diabetes Care. 2006, 29: 2130-2136. 10.2337/dc05-1973.PubMedCentralCrossRefPubMed
Metadata
Title
Screening for diabetes and hypertension in a rural low income setting in western Kenya utilizing home-based and community-based strategies
Authors
Sonak D Pastakia
Shamim M Ali
Jemima H Kamano
Constantine O Akwanalo
Samson K Ndege
Victor L Buckwalter
Rajesh Vedanthan
Gerald S Bloomfield
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Globalization and Health / Issue 1/2013
Electronic ISSN: 1744-8603
DOI
https://doi.org/10.1186/1744-8603-9-21

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