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Published in: Annals of General Psychiatry 1/2013

Open Access 01-12-2013 | Review

Electroconvulsive therapy use in adolescents: a systematic review

Authors: Nádia NR Lima, Vânia B Nascimento, Jorge AC Peixoto, Marcial M Moreira, Modesto LR Neto, José C Almeida, Carlos AC Vasconcelos, Saulo A Teixeira, Jucier G Júnior, Francisco TC Junior, Diego DM Guimarães, Aline Q Brasil, Jesus S Cartaxo, Marco Akerman, Alberto OA Reis

Published in: Annals of General Psychiatry | Issue 1/2013

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Abstract

Background

Considered as a moment of psychological vulnerability, adolescence is remarkably a risky period for the development of psychopathologies, when the choice of the correct therapeutic approach is crucial for achieving remission. One of the researched therapies in this case is electroconvulsive therapy (ECT). The present study reviews the recent and classical aspects regarding ECT use in adolescents.

Methods

Systematic review, performed in November 2012, conformed to the PRISMA statement.

Results

From the 212 retrieved articles, only 39 were included in the final sample. The reviewed studies bring indications of ECT use in adolescents, evaluate the efficiency of this therapy regarding remission, and explore the potential risks and complications of the procedure.

Conclusions

ECT use in adolescents is considered a highly efficient option for treating several psychiatric disorders, achieving high remission rates, and presenting few and relatively benign adverse effects. Risks can be mitigated by the correct use of the technique and are considered minimal when compared to the efficiency of ECT in treating psychopathologies.
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Literature
1.
go back to reference Hazell P: Depression in children and adolescents. Clin Evid (online). 2009, 2009: Hazell P: Depression in children and adolescents. Clin Evid (online). 2009, 2009:
2.
go back to reference Rolim-Neto ML, Silva TN, Assunção-Filho JKM, Carvalho RS, Teixeira SA, Lima NNR, Pedroso D, Cartaxo JS, Duarte Júnior JA, Demarzo MMP, Reis AAO: Childhood depression and psychocognitive development: description of causality relationships. Rev Bras Cresc Desenvolv Hum. 2011, 21 (3): 894-898. Rolim-Neto ML, Silva TN, Assunção-Filho JKM, Carvalho RS, Teixeira SA, Lima NNR, Pedroso D, Cartaxo JS, Duarte Júnior JA, Demarzo MMP, Reis AAO: Childhood depression and psychocognitive development: description of causality relationships. Rev Bras Cresc Desenvolv Hum. 2011, 21 (3): 894-898.
3.
go back to reference Baran B, Bitter I, Ungvári GS, Nagy Z, Gazdag G: The birth of biological therapy in Hungary: the story of László Meduna's first patient receiving convulsive therapy. Psychiatr Hung. 2008, 23 (5): 366-375.PubMed Baran B, Bitter I, Ungvári GS, Nagy Z, Gazdag G: The birth of biological therapy in Hungary: the story of László Meduna's first patient receiving convulsive therapy. Psychiatr Hung. 2008, 23 (5): 366-375.PubMed
4.
go back to reference Meduna L: Autobiography. Convuls Ther. 1985, 1: 43-57. 121–135 Meduna L: Autobiography. Convuls Ther. 1985, 1: 43-57. 121–135
5.
go back to reference Baran B, Bitter I, Ungvari GS, Gazdag G: The birth of convulsive therapy revisited: a reappraisal of László Meduna's first cohort of patients. J Affect Disord. 2012, 136 (3): 1179-1182. 10.1016/j.jad.2011.11.045.CrossRefPubMed Baran B, Bitter I, Ungvari GS, Gazdag G: The birth of convulsive therapy revisited: a reappraisal of László Meduna's first cohort of patients. J Affect Disord. 2012, 136 (3): 1179-1182. 10.1016/j.jad.2011.11.045.CrossRefPubMed
6.
go back to reference Wachtel LE, Dhossche DM, Kellner CH: When is electroconvulsive therapy appropriate for children and adolescents?. Med Hypotheses. 2011, 76 (3): 395-399. 10.1016/j.mehy.2010.11.001.CrossRefPubMed Wachtel LE, Dhossche DM, Kellner CH: When is electroconvulsive therapy appropriate for children and adolescents?. Med Hypotheses. 2011, 76 (3): 395-399. 10.1016/j.mehy.2010.11.001.CrossRefPubMed
7.
go back to reference Baeza I, Flamarique I, Garrido JM, Horga G, Pons A, Bernardo M, Morer A, Lázaro ML, Castro-Fornieles J: Clinical experience using electroconvulsive therapy in adolescents with schizophrenia spectrum disorders. J Child Adolesc Psychopharmacol. 2010, 20 (3): 205-209. 10.1089/cap.2009.0066.CrossRefPubMed Baeza I, Flamarique I, Garrido JM, Horga G, Pons A, Bernardo M, Morer A, Lázaro ML, Castro-Fornieles J: Clinical experience using electroconvulsive therapy in adolescents with schizophrenia spectrum disorders. J Child Adolesc Psychopharmacol. 2010, 20 (3): 205-209. 10.1089/cap.2009.0066.CrossRefPubMed
8.
go back to reference Conselho Federal de Medicina (Brazilian Federal Council of Medicine): Resolução CFM Nº 1640/2002. Dispõe sobre a eletroconvulsoterapia e dá outras providências. 2002, Brasília: CFM Conselho Federal de Medicina (Brazilian Federal Council of Medicine): Resolução CFM Nº 1640/2002. Dispõe sobre a eletroconvulsoterapia e dá outras providências. 2002, Brasília: CFM
9.
go back to reference Moher D, Liberati A, Tetzlaff I, Altman DG: Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009, 6 (7): e10097-CrossRef Moher D, Liberati A, Tetzlaff I, Altman DG: Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009, 6 (7): e10097-CrossRef
10.
go back to reference Strober M, Rao U, DeAntonio M, Liston E, Amaya-Jackson M, State L, Latz S: Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy. Biol Psychiatry. 1998, 43: 335-338. 10.1016/S0006-3223(97)00205-9.CrossRefPubMed Strober M, Rao U, DeAntonio M, Liston E, Amaya-Jackson M, State L, Latz S: Effects of electroconvulsive therapy in adolescents with severe endogenous depression resistant to pharmacotherapy. Biol Psychiatry. 1998, 43: 335-338. 10.1016/S0006-3223(97)00205-9.CrossRefPubMed
11.
go back to reference Gedge L, Beaudoin A, Lazowski L, Toit R, Jokic R, Milev R: Effects of electroconvulsive therapy and repetitive transcranial magnetic stimulation on serum brain-derived neurotrophic factor levels in patients with depression. Front Psychiatry. 2012, 3: 12-PubMedCentralCrossRefPubMed Gedge L, Beaudoin A, Lazowski L, Toit R, Jokic R, Milev R: Effects of electroconvulsive therapy and repetitive transcranial magnetic stimulation on serum brain-derived neurotrophic factor levels in patients with depression. Front Psychiatry. 2012, 3: 12-PubMedCentralCrossRefPubMed
12.
go back to reference Garg R, Chavan BS, Arun P: Quality of life after electroconvulsive therapy in persons with treatment resistant schizophrenia. Indian J Med Res. 2011, 133 (6): 641-644.PubMedCentralPubMed Garg R, Chavan BS, Arun P: Quality of life after electroconvulsive therapy in persons with treatment resistant schizophrenia. Indian J Med Res. 2011, 133 (6): 641-644.PubMedCentralPubMed
13.
go back to reference Shoirah H, Hamoda HM: Electroconvulsive therapy in children and adolescents. Expert Rev Neurother. 2011, 11 (1): 127-137. 10.1586/ern.10.178.CrossRefPubMed Shoirah H, Hamoda HM: Electroconvulsive therapy in children and adolescents. Expert Rev Neurother. 2011, 11 (1): 127-137. 10.1586/ern.10.178.CrossRefPubMed
14.
go back to reference Consoli A, Benmiloud M, Wachtel L, Dhossche D, Cohen D, Bonnot O: Electroconvulsive therapy in adolescents with the catatonia syndrome: efficacy and ethics. J ECT. 2010, 26 (4): 259-265. 10.1097/YCT.0b013e3181fb3924.CrossRefPubMed Consoli A, Benmiloud M, Wachtel L, Dhossche D, Cohen D, Bonnot O: Electroconvulsive therapy in adolescents with the catatonia syndrome: efficacy and ethics. J ECT. 2010, 26 (4): 259-265. 10.1097/YCT.0b013e3181fb3924.CrossRefPubMed
15.
go back to reference Antunes PB, Rosa MA, Belmonte-de-Abreu PS, Lobato MIR, Fleck MP: Electroconvulsive therapy in major depression: current aspects. Rev Bras Psiquiatr. 2009, 31 (Suppl. 1): S26-S33.CrossRefPubMed Antunes PB, Rosa MA, Belmonte-de-Abreu PS, Lobato MIR, Fleck MP: Electroconvulsive therapy in major depression: current aspects. Rev Bras Psiquiatr. 2009, 31 (Suppl. 1): S26-S33.CrossRefPubMed
16.
go back to reference Baghai TC, Moller HJ: Electroconvulsive therapy and its different indications. Dialogues Clin Neurosci. 2008, 10 (1): 105-117.PubMedCentralPubMed Baghai TC, Moller HJ: Electroconvulsive therapy and its different indications. Dialogues Clin Neurosci. 2008, 10 (1): 105-117.PubMedCentralPubMed
17.
go back to reference Feliu M, Edwards CL, Sudhakar S, McDougald C, Raynor R, Johnson S: Neuropsychological effects and attitudes in patients following electroconvulsive therapy. Neuropsychiatr Dis Treat. 2008, 4 (3): 613-617.PubMedCentralPubMed Feliu M, Edwards CL, Sudhakar S, McDougald C, Raynor R, Johnson S: Neuropsychological effects and attitudes in patients following electroconvulsive therapy. Neuropsychiatr Dis Treat. 2008, 4 (3): 613-617.PubMedCentralPubMed
18.
go back to reference Lévy-Rueff M, Jurgens A, Lôo H, Olié JP, Amado I: Maintenance electroconvulsive therapy and treatment of refractory schizophrenia. Encéphale. 2008, 34 (5): 526-533.CrossRefPubMed Lévy-Rueff M, Jurgens A, Lôo H, Olié JP, Amado I: Maintenance electroconvulsive therapy and treatment of refractory schizophrenia. Encéphale. 2008, 34 (5): 526-533.CrossRefPubMed
19.
go back to reference Arshad M, Arham AZ, Arif M, Bashir A, Bokutz M, Choudhary MM: Awareness and perceptions of electroconvulsive therapy among psychiatric patients: a cross-sectional survey from teaching hospitals in Karachi, Pakistan. BMC Psychiatry. 2007, 7: 27-10.1186/1471-244X-7-27.PubMedCentralCrossRefPubMed Arshad M, Arham AZ, Arif M, Bashir A, Bokutz M, Choudhary MM: Awareness and perceptions of electroconvulsive therapy among psychiatric patients: a cross-sectional survey from teaching hospitals in Karachi, Pakistan. BMC Psychiatry. 2007, 7: 27-10.1186/1471-244X-7-27.PubMedCentralCrossRefPubMed
20.
go back to reference Blaj A, Worrall A, Chaplin R: Electroconvulsive therapy: the practice and training needs of referring psychiatrists in the United Kingdom and Republic of Ireland. J ECT. 2007, 23 (2): 78-81. 10.1097/yct.0b013e3180544985.CrossRefPubMed Blaj A, Worrall A, Chaplin R: Electroconvulsive therapy: the practice and training needs of referring psychiatrists in the United Kingdom and Republic of Ireland. J ECT. 2007, 23 (2): 78-81. 10.1097/yct.0b013e3180544985.CrossRefPubMed
21.
go back to reference Datka W, Siwek M, Dudek D, Maczka G, Zieba A: Working memory disturbances in patients with major depression after ECT treatment. Psychiatr Pol. 2007, 41 (3): 339-349.PubMed Datka W, Siwek M, Dudek D, Maczka G, Zieba A: Working memory disturbances in patients with major depression after ECT treatment. Psychiatr Pol. 2007, 41 (3): 339-349.PubMed
22.
go back to reference Prakash J, Kotwal A, Prabhu H: Therapeutic and prophylactic utility of the memory-enhancing drug donepezil hydrochloride on cognition of patients undergoing electroconvulsive therapy: a randomized controlled trial. J ECT. 2006, 22: 163-168. 10.1097/01.yct.0000230365.81368.2d.CrossRefPubMed Prakash J, Kotwal A, Prabhu H: Therapeutic and prophylactic utility of the memory-enhancing drug donepezil hydrochloride on cognition of patients undergoing electroconvulsive therapy: a randomized controlled trial. J ECT. 2006, 22: 163-168. 10.1097/01.yct.0000230365.81368.2d.CrossRefPubMed
23.
go back to reference Salleh MA, Papakostas I, Zervas I, Christodoulou G: Eletroconvulsoterapia: critérios e recomendações da Associação Mundial de Psiquiatria. Rev Psiquiatr Clin. 2006, 33 (5): 262-267.CrossRef Salleh MA, Papakostas I, Zervas I, Christodoulou G: Eletroconvulsoterapia: critérios e recomendações da Associação Mundial de Psiquiatria. Rev Psiquiatr Clin. 2006, 33 (5): 262-267.CrossRef
24.
go back to reference Stein D, Weizman A, Bloch Y: Electroconvulsive therapy and transcranial magnetic stimulation: can they be considered valid modalities in the treatment of pediatric mood disorders?. Child Adolesc Psychiatr Clin N Am. 2006, 15 (4): 1035-1056. 10.1016/j.chc.2006.05.012.CrossRefPubMed Stein D, Weizman A, Bloch Y: Electroconvulsive therapy and transcranial magnetic stimulation: can they be considered valid modalities in the treatment of pediatric mood disorders?. Child Adolesc Psychiatr Clin N Am. 2006, 15 (4): 1035-1056. 10.1016/j.chc.2006.05.012.CrossRefPubMed
26.
go back to reference Sienaert P, De-Becker T, Vansteeldant K, Demyttenaere K, Peuskens J: Patient satisfaction after electroconvulsive therapy. J ECT. 2005, 21 (4): 227-231. 10.1097/01.yct.0000183268.62735.c0.CrossRefPubMed Sienaert P, De-Becker T, Vansteeldant K, Demyttenaere K, Peuskens J: Patient satisfaction after electroconvulsive therapy. J ECT. 2005, 21 (4): 227-231. 10.1097/01.yct.0000183268.62735.c0.CrossRefPubMed
27.
go back to reference Ghaziuddin N, Kutcher SP, Knapp P, Bernet W, Arnold V, Beitchman J, Benson RS, Bukstein O, Kinlan J, McClellan J, Rue D, Shaw JA, Stock S, Kroeger Ptakowski K, Work Group on Quality Issues: Practice parameter for use of electroconvulsive therapy with adolescents. J Am Acad Child Adolesc Psychiatry. 2004, 43 (12): 1521-1539.CrossRefPubMed Ghaziuddin N, Kutcher SP, Knapp P, Bernet W, Arnold V, Beitchman J, Benson RS, Bukstein O, Kinlan J, McClellan J, Rue D, Shaw JA, Stock S, Kroeger Ptakowski K, Work Group on Quality Issues: Practice parameter for use of electroconvulsive therapy with adolescents. J Am Acad Child Adolesc Psychiatry. 2004, 43 (12): 1521-1539.CrossRefPubMed
28.
go back to reference Segal J, Szabo CP, Toit J: Child and adolescent electroconvulsive therapy: a case report. World J Biol Psychiatry. 2004, 5 (4): 221-229. 10.1080/15622970410029937.CrossRefPubMed Segal J, Szabo CP, Toit J: Child and adolescent electroconvulsive therapy: a case report. World J Biol Psychiatry. 2004, 5 (4): 221-229. 10.1080/15622970410029937.CrossRefPubMed
29.
go back to reference Bloch Y, Levcovitch Y, Bloch AM, Mendlovic S, Ratzoni G: Electroconvulsive therapy in adolescents: similarities to and differences from adults. J Am Acad Child Adolesc Psychiatry. 2001, 40 (11): 1332-1336. 10.1097/00004583-200111000-00014.CrossRefPubMed Bloch Y, Levcovitch Y, Bloch AM, Mendlovic S, Ratzoni G: Electroconvulsive therapy in adolescents: similarities to and differences from adults. J Am Acad Child Adolesc Psychiatry. 2001, 40 (11): 1332-1336. 10.1097/00004583-200111000-00014.CrossRefPubMed
30.
go back to reference Daly JJ, Prudic J, Devanand DP, Nobler MS, Lisanby SH, Peyser S, Roose SP, Sackeim HA: ECT in bipolar and unipolar depression: differences in speed of response. Bipolar Disord. 2001, 3 (2): 95-104. 10.1034/j.1399-5618.2001.030208.x.CrossRefPubMed Daly JJ, Prudic J, Devanand DP, Nobler MS, Lisanby SH, Peyser S, Roose SP, Sackeim HA: ECT in bipolar and unipolar depression: differences in speed of response. Bipolar Disord. 2001, 3 (2): 95-104. 10.1034/j.1399-5618.2001.030208.x.CrossRefPubMed
31.
go back to reference Cohen D, Taieb O, Flament M: Absence of cognitive impairment at long-term follow-up in adolescents treated with ECT for severe mood disorders. Am J Psychiatry. 2000, 157: 460-462. 10.1176/appi.ajp.157.3.460.CrossRefPubMed Cohen D, Taieb O, Flament M: Absence of cognitive impairment at long-term follow-up in adolescents treated with ECT for severe mood disorders. Am J Psychiatry. 2000, 157: 460-462. 10.1176/appi.ajp.157.3.460.CrossRefPubMed
32.
go back to reference Ghaziuddin N, De-Quardo JR, Ghaziuddin M, King CA: Electroconvulsive therapy of a bipolar adolescent post-craniotomy for brain stem astrocytoma. J Child Adolesc Psychopharmacol. 1999, 9: 63-69. 10.1089/cap.1999.9.63.CrossRefPubMed Ghaziuddin N, De-Quardo JR, Ghaziuddin M, King CA: Electroconvulsive therapy of a bipolar adolescent post-craniotomy for brain stem astrocytoma. J Child Adolesc Psychopharmacol. 1999, 9: 63-69. 10.1089/cap.1999.9.63.CrossRefPubMed
33.
34.
go back to reference Kutcher S, Robertson HA: Electroconvulsive therapy in treatment-resistant bipolar youth. J Child Adolesc Psychopharmacol. 1995, 5: 167-175. 10.1089/cap.1995.5.167.CrossRef Kutcher S, Robertson HA: Electroconvulsive therapy in treatment-resistant bipolar youth. J Child Adolesc Psychopharmacol. 1995, 5: 167-175. 10.1089/cap.1995.5.167.CrossRef
35.
go back to reference Calev A: Neuropsychology and ECT: past and future research trends. Psychofarmacol Bull. 1994, 30: 461-469. Calev A: Neuropsychology and ECT: past and future research trends. Psychofarmacol Bull. 1994, 30: 461-469.
36.
go back to reference Parmar R: Attitudes of child psychiatrists to electroconvulsive therapy. Psychiatr Bull. 1993, 17: 12-13. 10.1192/pb.17.1.12.CrossRef Parmar R: Attitudes of child psychiatrists to electroconvulsive therapy. Psychiatr Bull. 1993, 17: 12-13. 10.1192/pb.17.1.12.CrossRef
37.
go back to reference Schneekloth TD, Rummans TA, Logan KM: Electroconvulsive therapy in adolescents. Convuls Ther. 1993, 9: 158-166.PubMed Schneekloth TD, Rummans TA, Logan KM: Electroconvulsive therapy in adolescents. Convuls Ther. 1993, 9: 158-166.PubMed
38.
go back to reference American Psychiatry Association Task Force on Electroconvulsive Therapy: The practice of ECT: recommendations for treatment, training and privileging. Convuls Ther. 1990, 6: 85-120. American Psychiatry Association Task Force on Electroconvulsive Therapy: The practice of ECT: recommendations for treatment, training and privileging. Convuls Ther. 1990, 6: 85-120.
39.
go back to reference Paillère-Martinot ML, Zivi A, Basquin M: Utilisation de l’ECT chez l’adolescent. Encéphale. 1990, 16: 399-404.PubMed Paillère-Martinot ML, Zivi A, Basquin M: Utilisation de l’ECT chez l’adolescent. Encéphale. 1990, 16: 399-404.PubMed
Metadata
Title
Electroconvulsive therapy use in adolescents: a systematic review
Authors
Nádia NR Lima
Vânia B Nascimento
Jorge AC Peixoto
Marcial M Moreira
Modesto LR Neto
José C Almeida
Carlos AC Vasconcelos
Saulo A Teixeira
Jucier G Júnior
Francisco TC Junior
Diego DM Guimarães
Aline Q Brasil
Jesus S Cartaxo
Marco Akerman
Alberto OA Reis
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Annals of General Psychiatry / Issue 1/2013
Electronic ISSN: 1744-859X
DOI
https://doi.org/10.1186/1744-859X-12-17

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