Published in:
Open Access
01-12-2014 | Poster presentation
Confocal microscopy reveals nerve fiber similarities in fibromyalgia and patients with dry eyes with a normal ophthalmic exam
Authors:
Daniel E Harper, Vincent Pallazola, David A Williams, Steven Harte, Daniel J Clauw, Roni M Shtein
Published in:
Molecular Pain
|
Special Issue 1/2014
Login to get access
Excerpt
Small fiber neuropathy has been shown in a subset of fibromyalgia patients, but this is a non-specific finding that has been noted in several chronic pain states. Small nerve fiber morphology can be measured non-invasively in the cornea, an area densely innervated with small fibers, using in-vivo confocal microscopy (IVCM). We used this technique to determine if 1) neuropathy is present in the corneas of fibromyalgia patients and 2) if those who suffer from idiopathic, chronic dry eyes (i.e., dry eye symptoms without dry eyes on exam) might also have compromised small fibers. …