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Journal of NeuroEngineering and Rehabilitation
Published in: Journal of NeuroEngineering and Rehabilitation 1/2007

Open Access 01-12-2007 | Review

An overview of tissue engineering approaches for management of spinal cord injuries

Author: Ali Samadikuchaksaraei

Published in: Journal of NeuroEngineering and Rehabilitation | Issue 1/2007

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Abstract

Severe spinal cord injury (SCI) leads to devastating neurological deficits and disabilities, which necessitates spending a great deal of health budget for psychological and healthcare problems of these patients and their relatives. This justifies the cost of research into the new modalities for treatment of spinal cord injuries, even in developing countries. Apart from surgical management and nerve grafting, several other approaches have been adopted for management of this condition including pharmacologic and gene therapy, cell therapy, and use of different cell-free or cell-seeded bioscaffolds. In current paper, the recent developments for therapeutic delivery of stem and non-stem cells to the site of injury, and application of cell-free and cell-seeded natural and synthetic scaffolds have been reviewed.
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Metadata
Title
An overview of tissue engineering approaches for management of spinal cord injuries
Author
Ali Samadikuchaksaraei
Publication date
01-12-2007
Publisher
BioMed Central
Published in
Journal of NeuroEngineering and Rehabilitation / Issue 1/2007
Electronic ISSN: 1743-0003
DOI
https://doi.org/10.1186/1743-0003-4-15

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